Výsledky vyhledávání - "G. Jitender Dev"

Synthesis of novel ethyl 2,4-disubstituted 8-(trifluoromethyl)pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine-9-carboxylate derivatives as promising anticancer agents

Autor: Banda Narsaiah, C. Ganesh Kumar, Yedla Poornachandra, G. Jitender Dev, D. Krishna Swaroop, N. Ravi Kumar

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 26:5203-5206

A series of novel pyrido[2′,3′:3,4] pyrazolo[1,5- a ]pyrimidine derivatives 6 – 9 were prepared in single step starting from 3-amino-6-(trifluoromethyl)-1 H -pyrazolo[3,4- b ]pyridine-5-carboxylate 5 on reaction with symmetrical and unsymmetric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aed54bbe7b5b737f7f5d5d5d76e689d
https://doi.org/10.1016/j.bmcl.2016.09.062

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Synthesis of novel triazole/isoxazole functionalized 7-(trifluoromethyl)pyrido[2,3- d ]pyrimidine derivatives as promising anticancer and antibacterial agents

Autor: S. Nishant Jain, D. Krishna Swaroop, G. Jitender Dev, G. Bharath, N. Ravikumar, A. Gangagni Rao, B. Debanjan, R. Naresh Kumar, Banda Narsaiah

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 26:2927-2930

A series of novel 1,2,3-triazole/isoxazole functionalized pyrido[2,3-d]pyrimidine derivatives 6a-c, 7a-h and 8a-e were prepared in series of synthetic steps. All the compounds screened for the anticancer activity against four human cancer cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4120a3ac1d4ef6dd7cc5adadd68826
https://doi.org/10.1016/j.bmcl.2016.04.038

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Studies on synthesis of novel pyrido[2,3-d]pyrimidine derivatives, evaluation of their antimicrobial activity and molecular docking

Autor: G. Shravan Kumar, C. Ganesh Kumar, Banda Narsaiah, Yedla Poornachandra, G. Jitender Dev, Devarapaga Madhu, B. Veeraswamy

Publikováno v: Bioorganicmedicinal chemistry letters. 28(9)

A series of novel pyrido[2,3-d]pyrimidine derivatives 6 were prepared starting from 2-amino-3-cyano-4-trifluoromethyl-6-phenyl pyridine 3 via Grignard’s reaction, cyclization followed by coupling with aliphatic and cyclic amines. All the compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abfa89e592fb402498493f80ac76cb5
https://pubmed.ncbi.nlm.nih.gov/29602683

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An efficient method for the synthesis of 1,2,3-triazole functionalized isoxazolidine derivatives by 1,3-dipolar cycloaddition of nitrones with terminal olefins

Autor: P. Sambasiva Rao, K. Chinna Ashalu, G. Jitender Dev, N. Ravi Kumar, PVSS Srinivas, B. V. Thomas, B. Narsaiah

1-Phenyl-1,2,3-triazole-4-carbaldehyde 1 was treated with different N-alkyl hydroxylamine hydrochlorides 2 using NaHCO3 to obtain 1,2,3-triazole substituted N-alkyl nitrones 3a-c. The nitrones 3a-c were further reacted with different substituted olef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5820ce6327563f1884869bdc6bb264f1

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Efficient method for the synthesis of 1,2,3-triazole functionalized isoxazolidine derivatives by 1,3-dipolar cycloaddition of nitrones with terminal olefins

Autor: P.V. Srinivas, Banda Narsaiah, N. Ravi Kumar, G. Jitender Dev, K. Chinna Ashalu, B. V. Thomas, P. Sambasiva Rao

1-Phenyl-1,2,3-triazole-4-carbaldehyde 1 was treated with different N-alkyl hydroxylamine hydrochlorides 2 using NaHCO3 to obtain 1,2,3-triazole substituted N-alkyl nitrones 3a–c. The nitrones 3a–c were further reacted with different substituted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e58aabadd19136a58f078a5f0d74d05

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Synthesis of novel amide functionalized 2H-chromene derivatives by Ritter amidation of primary alcohol using HBF4·OEt2 as a mild and versatile reagent and evaluation of their antimicrobial and anti-biofilm activities

Autor: Banda Narsaiah, Jagadeesh Babu Nanubolu, G. Jitender Dev, Yedla Poornachandra, G. Mallareddy, C. Ganesh Kumar, K. Ratnakar Reddy

Publikováno v: Bioorganicmedicinal chemistry letters. 25(15)

A series of novel amide functionalized 2H-chromene derivatives 3 were prepared starting from ethyl-2-hydroxy-2-(trifluoromethyl)-2H-chromene-3-carboxylate 1 via sodium borohydride reduction followed by Ritter amidation using HBF4·OEt2 as a mild and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c635abb96fe79a905127a9c203463fcb
https://pubmed.ncbi.nlm.nih.gov/26048810

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Synthesis of novel 1,2,3-triazole/isoxazole functionalized 2H-Chromene derivatives and their cytotoxic activity

Autor: K. Ratnakar Reddy, P. Shanthan Rao, P. Sambasiva Rao, C. Ganesh Kumar, Yedla Poornachandra, G. Jitender Dev, Banda Narsaiah

Publikováno v: Bioorganicmedicinal chemistry letters. 24(7)

A series of novel 2-(1,2,3-triazolylmethoxy) 5a – q and isoxazole tagged 6a – g 2 H -Chromene derivatives were prepared starting from salicylaldehyde and ethyl-4,4,4-trifluoroacetoacetate via cyclization to form ethyl 2-hydroxy-2-(trifluoromethyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abff07d28c24bee1cecf9978daacd6c4
https://pubmed.ncbi.nlm.nih.gov/24641975

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