Zobrazeno 1 - 10
of 37
pro vyhledávání: '"G. J. Swansbury"'
Autor:
G. J. Swansbury, Paul Mitchell, Kuan A, Stanley W. Ashley, R. L. Powles, Samar Kulkarni, T. J. Powles, Jennifer Treleaven, Radovan Saso, Jayesh Mehta
Publikováno v:
British Journal of Cancer
Of 1774 patients with breast cancer given mitoxantrone (MTZ) with methotrexate (n = 492) or with methotrexate and mitomycin C (n = 1282), nine developed MDS/AML after a median of 2.5 years. Median duration of survival from diagnosis of MDS/AML was 10
Autor:
R. L. Powles, A Atra, Toon Min, G. J. Swansbury, Daniel Catovsky, Clive Horton, Melissa Dainton, Durosinmi Ma, Estela Matutes, Jennifer Treleaven, K. Rege
Publikováno v:
Leukemia & Lymphoma. 40:67-77
Over a period of 14 years, 50 patients (12 children and 38 adults) of whom 46 had acute myeloid leukemia (AML) and 4 had myelodysplastic syndrome characterized by the t(8;21)(q22;q22) translocation were referred to the Royal Marsden Hospital. The cli
Publikováno v:
British Journal of Haematology. 106:515-519
We report the long-term follow-up results on two groups of patients with hairy cell leukaemia (HCL) treated with either pentostatin (deoxycoformycin) or cladribine (2-chlorodeoxyadenosine). 165 HCL patients received treatment with pentostatin (betwee
Autor:
S Killick, Jennifer Treleaven, Melissa Dainton, G. J. Swansbury, J L Bueno, D M Hughes, A Watson
Publikováno v:
Leukemia & Lymphoma. 32:381-384
Monosomy X as the sole acquired cytogenetic abnormality is usually found in myeloid hematological malignancies, especially those with myelodysplastic features. Only three cases of acute lymphoblastic leukemia (ALL) with this abnormality have been pre
Autor:
G. J. Swansbury
Publikováno v:
Cancer Genetics and Cytogenetics. 104:139-145
The detection of clones by conventional cytogenetic studies in diagnostic hematoncology is heavily subject to the effects of many biological and laboratory factors, one of which is the number of divisions analyzed. Data from 20 laboratories were comb
Publikováno v:
British Journal of Haematology. 99:93-100
We have analysed the prognostic influence of cytogenetic findings at diagnosis in a group of 502 children with acute lymphoblastic leukaemia (ALL), treated on MRC UKALL X, in whom clonal cytogenetic abnormalities were detected at diagnosis. Despite t
Autor:
A Zomas, Lynne R. Hiorns, Ross Pinkerton, N Farahat, Toon Min, Estela Matutes, Daniel Catovsky, G. J. Swansbury
Publikováno v:
Leukemia & Lymphoma. 25:179-185
We describe a case of bilineal leukemia in a 5-year old boy with a rare immunophenotype and the novel translocation t(9;17)(p11;q11) as the sole chromosomal abnormality. Two immunologically distinct blast cell subsets expressed T-markers (CD2, CD5, C
Autor:
M. S. J. Dyer, S. E. Height, G. J. Swansbury, Jennifer Treleaven, Estela Matutes, Daniel Catovsky
Publikováno v:
Scopus-Elsevier
Clonal rearrangements of the Ig heavy chain (IGH) locus occur in nearly all cases of B-cell precursor acute leukemia (BCP-ALL). Some of these rearrangements may be detected by polymerase chain reaction (PCR) using VH gene framework III (FRIII) and JH
Autor:
R. Gillingham, Terry J. Hamblin, D. Lens, G. J. Swansbury, J. Garcia-Marco, J. Ellis, D. Catovsky, David Oscier, A. Copplestone, Estela Matutes
Publikováno v:
British Journal of Haematology. 92:382-388
We have analysed the clinical and laboratory features in 544 patients with chronic lymphocytic leukaemia (CLL) with available cytogenetics and fluorescence in-situ hybridization (FISH) analysis for trisomy 12 in half of them, to examine the correlati
Autor:
V. Shepherd, J. B. G. Bell, S. Cabral, Jennifer Treleaven, Seema Singhal, Toon Min, B. C. Millar, G. J. Swansbury, Jayesh Mehta, R. L. Powles
Publikováno v:
Leukemia & Lymphoma. 23:107-111
Five patients with Ph+ chronic myeloid leukemia and no detectable diploid cells in the marrow received 6 g hydroxyurea twice daily for 7 days followed by G-CSF to harvest Ph-cells 1-84 months after diagnosis. Three were in first chronic phase, and tw