Zobrazeno 1 - 10
of 12
pro vyhledávání: '"G. J. Southan"'
Autor:
I. G. Obrosova, Omorodola I. Abatan, Fei Li, G. J. Southan, T. Charniauskaya, Pal Pacher, Csaba Szabó, Martin J. Stevens
Publikováno v:
Diabetologia. 47:710-717
Aims/hypothesis. Poly(ADP-ribose) polymerase activation depletes NAD + and high-energy phosphates, activates protein kinase C, and affects gene expression in various tissues. This study was designed to characterise the effects of the potent, orally a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2075102b785eceb2eb732758161d42f0
https://doi.org/10.1007/s00125-004-1356-0
https://doi.org/10.1007/s00125-004-1356-0
Publikováno v:
Pancreas. 28:e39-e44
Inhibition of inducible nitric oxide synthase has been shown to be antiinflammatory in a variety of disease states. Type I diabetes is an autoimmune disease resulting from the specific destruction of the insulin-producing pancreatic beta cells. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d159f07393605a87b3b904e9f4479a
https://doi.org/10.1097/00006676-200403000-00018
https://doi.org/10.1097/00006676-200403000-00018
Autor:
Pal Pacher, Lucas Liaudet, G. J. Southan, Galaleldin E. Abdelkarim, Oleg V. Evgenov, Jon G. Mabley, A. L. Salzman, Csaba Szabó
Publikováno v:
International Journal of Impotence Research. 15:461-464
The aim of the present study was to test the effects of a topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), on vaginal blood flow and hemodynamics in rats. Laser Doppler flowmetry was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ace2c82fbaab13ba25c025cfa3ca504
https://doi.org/10.1038/sj.ijir.3901045
https://doi.org/10.1038/sj.ijir.3901045
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 300:876-881
Nicotine has been previously shown to have immunosuppressive actions. Type I diabetes is an autoimmune disease resulting from the specific destruction of the insulin-producing pancreatic beta-cells. Thus, we hypothesized that nicotine may exert prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282d5ba925422e6daf28bcaede678951
https://doi.org/10.1124/jpet.300.3.876
https://doi.org/10.1124/jpet.300.3.876
Publikováno v:
Biochemical and Biophysical Research Communications. 203:1638-1644
The observation that spermine inhibits the endotoxin (lipopolysaccharide; LPS) induced production of nitric oxide (NO) in macrophages has been ascribed to the conversion of SP to active metabolites by the action of enzymes, such as diamine oxidases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcabf0661df7e74113169f7f3d51f333
https://doi.org/10.1006/bbrc.1994.2374
https://doi.org/10.1006/bbrc.1994.2374
Autor:
N. Unnadkat, Andrew T. Kicman, David A. Cowan, G. J. Southan, Christopher J. Walker, R V Brooks
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 42:87-94
Dihydrotestosterone (DHT) can be used by an athlete as an anabolic steroid to evade the current International Olympic Committee approved drug tests. To investigate the possibility of a method for its detection, the heptanoate ester of DHT was adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6c867cd881a954acc08a5d572658ce
https://doi.org/10.1016/0960-0760(92)90014-a
https://doi.org/10.1016/0960-0760(92)90014-a
Autor:
J G, Mabley, G, Haskó, L, Liaudet, F G, Soriano, F, Soriano, G J, Southan, A L, Salzman, C, Szabó
Publikováno v:
The Journal of endocrinology. 173(3)
Insulin-dependent diabetes mellitus (IDDM) is a disease characterized by the autoimmune destruction of the pancreatic beta-cells, which requires the expression of a number of immune-related genes including major histocompatibility complex proteins, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b6469a2d6d8c779a97a91cf2ea7285
https://pubmed.ncbi.nlm.nih.gov/12065235
https://pubmed.ncbi.nlm.nih.gov/12065235
Autor:
A. L. Salzman, G. J. Southan, László Virág, Csaba Szabó, P. Jagtap, Éva Szabó, Jon G. Mabley, Anita Marton, Galaleldin E. Abdelkarim, Lucas Liaudet, Francisco Garcia Soriano, G. Haskó, Mauro Perretti, Stephen J. Getting
Objective and design: Oxygen- and nitrogen-derived free radicals and oxidants play an important role in the pathogenesis of various forms of inflammation. Recent work emphasizes the importance of oxidant-induced DNA strand breakage and activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dd0c3e0372d9fb8f7a3e109de6a1aa
Autor:
G. Haskó, G. J. Southan, Csaba Szabó, John G. Mabley, A. L. Salzman, Lucas Liaudet, Francisco Garcia Soriano
Publikováno v:
Journal of Endocrinology. 206:247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d88319c666e2e3501339a95ba17645b
https://doi.org/10.1677/joe.0.1730457e
https://doi.org/10.1677/joe.0.1730457e
Autor:
S C Collyer, Andrew T. Kicman, David A. Cowan, Michael J. Wheeler, G. J. Southan, M N Nanjee, R V Brooks
A detection method for testosterone administration was developed using radioimmunoassay to measure the urinary ratios of testosterone (T) to epitestosterone (E) and to luteinizing hormone (LH). A comparative study of the effect on these ratios of a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a104a1557da6356bb738d6735ac09b2
https://europepmc.org/articles/PMC1478898/
https://europepmc.org/articles/PMC1478898/