Zobrazeno 1 - 10
of 532
pro vyhledávání: '"G. J. Kelloff"'
Autor:
Konstantin Christov, Albert Green, G J Kelloff, Anne Shilkaitis, Vernon E. Steele, Ronald A. Lubet
Publikováno v:
Carcinogenesis. 21:227-233
Previous studies have shown that terminal end buds (TEBs) in the murine mammary gland have high proliferative activity and demonstrate apoptotic cell death (ACD). Since TEBs are considered the place of origin of most chemically induced mammary carcin
Publikováno v:
Carcinogenesis. 19:2133-2138
Molecular epidemiological studies of populations at high risk for liver cancer have shown that hepatitis B virus (HBV) and aflatoxin B1 exposures are two major risk factors for this disease. Oltipraz is currently being considered for clinical trial t
Autor:
G J Kelloff, Meenakshi Singh, Vernon E. Steele, Pam Wolfe, Henry J. Thompson, John N. McGinley
Publikováno v:
Carcinogenesis. 19:2181-2185
An experimental model for mammary carcinogenesis has been described in which intraductal proliferations, ductal carcinomas in situ and adenocarcinomas can be readily detected and the frequency of their occurrence quantified. The objective of the expe
Autor:
Isao Eto, Clinton J. Grubbs, G J Kelloff, Vernon E. Steele, R DeCoster, Ming You, C Bowden, M. Margaret Juliana, Lubet Ra
Publikováno v:
Carcinogenesis. 19:1345-1351
The chemopreventive activity of the highly specific nonsteroidal aromatase inhibitor, vorozole, was examined in the methylnitrosourea (MNU)-induced rat model of mammary carcinogenesis. Various doses of vorozole (0.08-1.25 mg/kg body wt/day) were admi
Autor:
V. E. Steele, D. Bagheri, D. A. Balentine, C. W. Boone, R. Mehta, M. A. Morse, S. Sharma, C. C. Sigman, G. D. Stoner, M. J. Wargovich, J. H. Weisburger, S. Zhu, G. J. Kelloff
Publikováno v:
Experimental Biology and Medicine. 220:210-212
Autor:
G. J. Kelloff, C. C. Sigman
Publikováno v:
Mechanisms in Carcinogenesis and Cancer Prevention ISBN: 9783642078590
The potential role of products of arachidonic acid (AA) metabolism in carcinogenesis has been reviewed extensively (Kelloff et al. 1994; Marnett 1995; Taketo 1998a,b; Dannenberg et al. 2001; Funk 2001), as have cancer prevention strategies based on m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4501b2f3ba3d6aba872f397694d9c8
https://doi.org/10.1007/978-3-662-08602-5_11
https://doi.org/10.1007/978-3-662-08602-5_11
Publikováno v:
Prostate cancer and prostatic diseases. 2(S1)
Because prostate cancer has a long latency and high incidence, it is a good target for chemoprevention by agents such as retinoids, antiandrogens, antiestrogens, and vitamin D analogs. Phase II chemoprevention trials are frequently conducted on cohor
Publikováno v:
Anticancer research. 21(6A)
One of the approaches in chemoprevention to prevent or delay the progression of precancerous lesions, is to apply chemopreventive agents that can potentially block angiogenesis. A quantitative in vivo angiogenesis inhibition assay was developed to te