Zobrazeno 1 - 7
of 7
pro vyhledávání: '"G. J. Jochems"'
Publikováno v:
Human Antibodies. 4:124-133
To study the role of interleukin (IL)-6 as a growth and differentiation factor for Epstein-Barr virus (EBV)-transformed B lymphocytes, we transfected the cDNA coding for human IL-6 in a monoclonal IgG1-secreting EBV B cell line. Two independent clone
Publikováno v:
Human Antibodies. 3:162-167
Epstein-Barr virus (EBV)-transformed cell lines constitutively secrete lymphotoxin (LT/TNF beta) and not tumor necrosis factor-alpha (TNF alpha). To analyze the cellular processes that regulate LT and TNF alpha secretion by lymphoblastoid cell lines,
Autor:
T. H. Frame, Michèl R. Klein, G. J. Jochems, R. V. W. Van Eijk, Richard J. Bende, R. A. W. Van Lier, W. P. Zeijlemaker
Publikováno v:
Cellular immunology, 143(2), 310-323. Academic Press Inc.
In the present study we investigated whether interleukin-4 (IL-4), IL-5, and IL-6 could enhance the efficiency of Epstein-Barr virus (EBV) transformation for the generation of specific human monoclonal antibody (HuMAb)-producing B-cell lines directed
Autor:
Michèl R. Klein, van Boxtel-Oosterhof F, W. P. Zeijlemaker, van Lier Ra, R. Jordens, G. J. Jochems, Pascual-Salcedo D
Publikováno v:
Human antibodies and hybridomas, 2(2), 57-64. Butterworth Scientific Ltd.
Scopus-Elsevier
Scopus-Elsevier
To optimize growth and Ig production of in vitro-cultured Epstein-Barr virus (EBV)-transformed B cells, a panel of six monoclonal EBV B-cell lines was analyzed for autocrine growth factor production and responsiveness to various cytokines. Three cell
Publikováno v:
Human antibodies and hybridomas. 3(4)
Epstein-Barr virus (EBV)-transformed cell lines constitutively secrete lymphotoxin (LT/TNF beta) and not tumor necrosis factor-alpha (TNF alpha). To analyze the cellular processes that regulate LT and TNF alpha secretion by lymphoblastoid cell lines,
Autor:
G J, Jochems, M R, Klein, R, Jordens, D, Pascual-Salcedo, F, van Boxtel-Oosterhof, R A, van Lier, W P, Zeijlemaker
Publikováno v:
Human antibodies and hybridomas. 2(2)
To optimize growth and Ig production of in vitro-cultured Epstein-Barr virus (EBV)-transformed B cells, a panel of six monoclonal EBV B-cell lines was analyzed for autocrine growth factor production and responsiveness to various cytokines. Three cell
Publikováno v:
Developments in biological standardization. 71
To optimalize growth and Ig production of EBV transformed B cells for large scale tissue culture, we analyzed five stable monoclonal EBV-B cell lines for their responsiveness to interleukin (IL)-6 in standard medium with 5% FCS and in several serum-f