Zobrazeno 1 - 10
of 13
pro vyhledávání: '"G. J. Haluska"'
Autor:
C. J. Woyden, M. J. Novy, Mark G. Bock, Bradley V. Clineschmidt, B. E. Evans, E V Lis, Terry W. Schorn, K. L. Thompson, Peter K. S. Siegl, Douglas J. Pettibone, Duane R. Reiss, Peter D. Williams, Doug W. Hobbs, M. A. Cukierski, Maribeth T. Guidotti, Roger M. Freidinger, D. F. Veber, G. J. Haluska, M. J. Cook, M. J. Kaufman, S.-H. L. Chiu
Publikováno v:
Drug Development Research. 30:129-142
L-368,899 [1S-(-7,7-dimethyl-2-endo-(2S-amino-4-(methylsulfonyl)butyramido)-bicyclo(2.2.1)-heptan-1-yl)methanesulfonyl)-4-(2-methylphenyl)piperazine] was characterized in vitro and in vivo as a potent and selective, orally bioavailable oxytocin (OT)
Publikováno v:
Journal of the Society for Gynecologic Investigation. 9(3)
It is not known whether withdrawal of progesterone (P) action is a prerequisite for parturition in women or in nonhuman primates because concentrations of circulating progesterone or progesterone receptors (PR) in myometrium and decidua do not decrea
Autor:
C L, Bethea, M G, Gravett, D W, Sadowsky, G J, Haluska, M K, Axthelm, M J, Novy, M K, Axethelm
Publikováno v:
Biology of reproduction. 58(6)
Amniotic fluid contains a high concentration of prolactin produced and secreted by the decidua. In vitro models have suggested that bacterial products inhibit prolactin secretion by decidual cells. To further examine this potentially important regula
Publikováno v:
Biology of reproduction. 57(4)
Recent evidence suggests that progesterone is required for ovulation, luteinization, and the maintenance of luteal structure and function in primates. Progesterone action is mediated by intracellular progesterone receptors (PRs), and PRs are detectab
Publikováno v:
Journal of the Society for Gynecologic Investigation. 3(3)
To describe the temporal and quantitative consequences of intra-amniotic interleukin-1 beta infusion in a nonhuman primate model.On days 128-138 of gestation (term 167 days), four chronically instrumented rhesus monkeys (Macaca mulatta) underwent ser
Publikováno v:
Biology of reproduction. 51(4)
The production of prostaglandins from amnion, chorion, decidua, and myometrium was studied in a superfusion system to determine the level of prostaglandin production during late pregnancy, during spontaneous labor, and after in vivo treatment with RU
Publikováno v:
Biology of reproduction. 46(4)
Equine relaxin has been previously determined in a small number of pregnant Thoroughbred mares. To better define the normal pregnancy pattern of relaxin, the current study reports on a much larger number of mares. It also was designed to determine if
Autor:
B V, Clineschmidt, D J, Pettibone, D R, Reiss, E V, Lis, G J, Haluska, M J, Novy, M J, Cook, M A, Cukierski, M J, Kaufman, M G, Bock
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 256(3)
Two cyclic hexapeptides unrelated in chemical structure to oxytocin (OT) were shown in vivo to be antagonists of the contractile action of OT on the uterus. In anesthetized rats challenged with OT (1 micrograms/kg) administered as an i.v. bolus, L-36
Autor:
W. B. Currie, G. J. Haluska
Publikováno v:
Reproduction. 84:635-646
Concentrations of plasma progesterone were similar to values reported in the literature except that a significant decrease in progesterone during the last day, but before parturition, was detected by systematic, high-intensity blood sampling. Mean co
Publikováno v:
Reproduction. 81:471-478
Recordings of uterine electrical activity were made from 5 pregnant pony mares from Day 141 to 320 of pregnancy. Three types of activity were identified. Short, medium and long bursts were quantified as the percentage of time each occurred during the