Výsledky vyhledávání - "G. J. Graepel"

Effect of hyperglycemia and the aldose reductase inhibitor tolrestat on sural nerve biochemistry and morphometry in advanced diabetic peripheral polyneuropathy. The Tolrestat Study Group

Autor: A A, Sima, D A, Greene, M B, Brown, T C, Hohman, D, Hicks, G J, Graepel, W J, Bochenek, M, Beg, B, Gonen

Publikováno v: Journal of diabetes and its complications. 7(3)

Tolrestat is a well tolerated nonhydantoin aldose reductase inhibitor that has been reported to improve nerve conduction in diabetic animals and humans. Its effects on nerve biochemistry and structure have not been studied in patients with diabetic n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e08ad30aaa9b23c199e035a6fe5a6055
https://pubmed.ncbi.nlm.nih.gov/8343610

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Withdrawal of the aldose reductase inhibitor tolrestat in patients with diabetic neuropathy: effect on nerve function. The Tolrestat Study Group

Autor: J V, Santiago, P H, Snksen, A J, Boulton, A, Macleod, M, Beg, W, Bochenek, G J, Graepel, B, Gonen

Publikováno v: Journal of diabetes and its complications. 7(3)

A double-blind, placebo-controlled clinical trial was conducted to study the effects of discontinuing tolrestat, an aldose reductase inhibitor, on peripheral sensorimotor diabetic neuropathy. After an average of 4.2 years of continuous tolrestat use,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1978ce4e0e4a05b3792446cb62cdb37c
https://pubmed.ncbi.nlm.nih.gov/8343611

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Effect of lanthanum chloride on established atherosclerosis in the cholesterol-fed rabbit. Mitral valve as a site for assessment of treatment effects

Autor: G. J. Graepel, Candy S. Robinson, B. Y. Cockrell, Peter J. Gillies

Publikováno v: Arteriosclerosis: An Official Journal of the American Heart Association, Inc.. 9:253-260

The ability of lanthanum chloride (LaCl3) to retard the progression of established atherosclerosis was investigated in cholesterol-fed rabbits. Rabbits were initially maintained on a high-fat plus cholesterol-supplemented diet for 10 weeks to induce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846e1cc88c4d8c3a21f0c4e93ad4ed18
https://doi.org/10.1161/01.atv.9.2.253

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Abnormal estrogen conjugation in women at risk for familial breast cancer at the periovulatory stage of the menstrual cycle

Autor: J, Fishman, H L, Bradlow, D K, Fukushima, J, O'Connor, R S, Rosenfeld, G J, Graepel, R, Elston, H, Lynch

Publikováno v: Cancer research. 43(4)

The present study was designed to establish whether women with a family history of breast cancer exhibit endocrine abnormalities which could be responsible for their increased risk for the disease. Plasma hormone levels were measured every second day

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03c0d8bac619af524933bc94f6f69412
https://pubmed.ncbi.nlm.nih.gov/6831424

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