Zobrazeno 1 - 10
of 42
pro vyhledávání: '"G. J. Goldenberg"'
Autor:
J P, McPherson, G J, Goldenberg
Publikováno v:
Cancer research. 58(20)
DNA topoisomerase II (topo II) is an essential nuclear enzyme required for chromatin condensation and chromosome segregation during mitosis. Forced overexpression of topo IIalpha was found to cause morphological changes in recipient cells associated
Publikováno v:
Anticancer research. 17(6D)
Previous studies have demonstrated decreased levels of DNA topoisomerase II alpha protein and messenger RNA in the Adriamycin-resistant P388 murine leukemia cell line P388/ADR/7 compared to the sensitive P388/4 cell line. An allelic fusion event invo
Autor:
G A, Brown, J P, McPherson, L, Gu, D W, Hedley, R, Toso, K L, Deuchars, M H, Freedman, G J, Goldenberg
Publikováno v:
Cancer research. 55(1)
The levels of expression of topoisomerase II alpha and topoisomerase II beta were investigated in six established cell lines of human childhood acute lymphoblastic leukemia (ALL) as a function of doubling time, cell cycle distribution, and of sensiti
Autor:
G L, Stelmack, G J, Goldenberg
Publikováno v:
Cancer research. 53(15)
The level of induction of three cytosolic glutathione-S-transferase (GST) classes has been compared in L5178Y murine lymphoblasts resistant to either the quinone-containing compound, hydrolyzed benzoquinone mustard (HBM), or the aromatic alkylating a
Publikováno v:
Journal of Biological Chemistry. 254:1057-1064
Previous studies have shown that uptake of several alkylating agents occurs by independent transport mechanisms. Uptake of one of these agents, the phenylalanine derivative of nitrogen mustard (melphalan), has been investigated in LPC-1 plasmacytoma
Publikováno v:
Cancer research. 47(15)
We have previously reported the identification and characterization of a prolactin-inducible protein (PIP) as well as the cloning of the gene encoding PIP in cultured human breast cancer cells. We now present three lines of evidence that the gene enc
Autor:
G J, Goldenberg, L J, Brandes
Publikováno v:
Cancer research. 36(2 pt 2)
Epstein-Barr virus, the apparent cause of infectious mononucleosis, may also be an etiological agent in nasopharyngeal carcinoma and Burkitt's lymphoma. Lymphocytes from normal individuals with anti-Epstein-Barr virus antibody activity may be sensiti
Autor:
G J, Goldenberg, B K, Sinha
Publikováno v:
Cancer research. 33(11)
Publikováno v:
Cancer research. 37(4)
The mechanism of uptake of nitrosoureas by L5178Y cells in vitro was investigated. A time course of the uptake of radioactivity on incubation of L5178Y lymphoblast with [14C]-1,3-bis(2-chloroethyl)-1-nitrosourea was linear for 30 min and then entered
Publikováno v:
British journal of haematology. 27(1)