Zobrazeno 1 - 10
of 530
pro vyhledávání: '"G. J. Durant"'
Publikováno v:
Agents and Actions. 43:132-138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d7754b1b337a4aeffd1a9e2fd055126
https://doi.org/10.1007/bf01986679
https://doi.org/10.1007/bf01986679
Publikováno v:
Agents and Actions. 43:139-143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::538c5cf04afb7385cbd32e37466c677d
https://doi.org/10.1007/bf01986680
https://doi.org/10.1007/bf01986680
Autor:
David J. Watkin, Keith Prout, G. J. Durant, D. G. Cooper, Ch R Ganellin, K. Burns, G. S. Sach
Publikováno v:
Acta Crystallographica Section B Structural Science. 49:547-559
The crystal and molecular structures of the following compounds showing histamine H2-antagonist activity have been determined: (1) N-Cyano-N'-methyl-N"-12[(2-pyridyl)methylthi_'o]ethyl } guanidine, C 11H 15 N5 S, Mr = 249.33, triclinic, P1, a = 7.482
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cd0f8d47f2e75a28e25c8a162f6bdb7
https://doi.org/10.1107/s0108768193000217
https://doi.org/10.1107/s0108768193000217
Autor:
Y. G. J. Durant, Jean Guillot
Publikováno v:
Colloid & Polymer Science. 271:607-615
In seeded emulsion polymerization, during the second stage, new interfaces appear and the surface area changes. A thermodynamic equilibrium approach is presented which predicts particle morphology of a whole range of non-spherical particles upon poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60083e17d9bd12ea1566298e6f66533
https://doi.org/10.1007/bf00657992
https://doi.org/10.1007/bf00657992
Publikováno v:
ChemInform. 24
5-(1,3-Benzodioxol-5-ylmethyl)-2-[2-(5-methyl-1H-imidazol-4-ylmethylthio)ethylamino]-4(1H)-pyrimidone dihydrochloride C 19 H 23 N 5 O 3 S 2+ .2Cl - , M r =472.4, triclinic, P1l, a=8.291 (2), b=10.759 (3), c=13.169 (3) A, α=108.42 (2), β=93.28 (2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92a51e060609099c045a7a28982b6ca5
https://doi.org/10.1002/chin.199316047
https://doi.org/10.1002/chin.199316047
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 49:44-46
5-(1,3-Benzodioxol-5-ylmethyl)-2-[2-(5-methyl-1H-imidazol-4-ylmethylthio)ethylamino]-4(1H)-pyrimidone dihydrochloride C 19 H 23 N 5 O 3 S 2+ .2Cl - , M r =472.4, triclinic, P1l, a=8.291 (2), b=10.759 (3), c=13.169 (3) A, α=108.42 (2), β=93.28 (2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8d0c1da74215f171a2386314f3b951b
https://doi.org/10.1107/s0108270192003548
https://doi.org/10.1107/s0108270192003548
Autor:
G. J. Durant, R W Brimblecombe, J W Black, Michael E. Parsons, Charon R. Ganellin, W. A. M. Duncan
Publikováno v:
British Journal of Pharmacology. 160:S52-S53
Burimamide and metiamide which have been described previously (Black, Duncan, Durant, Ganellin & Parsons, 1972; Black, Duncan, Emmett, Ganellin, Hesselbo, Parsons & Wyllie, 1973) are histamine H2-receptor antagonists. This communication describes som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49842e38e7b379387b96123b07fafd2b
https://doi.org/10.1111/j.1476-5381.2010.00854.x
https://doi.org/10.1111/j.1476-5381.2010.00854.x
Autor:
C E, Tedford, S L, Yates, G P, Pawlowski, J W, Nalwalk, L B, Hough, M A, Khan, J G, Phillips, G J, Durant, R C, Frederickson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(2)
GT-2016, a non-thiourea-containing imidazole, has been developed as a histamine H3 antagonist. In vitro and in vivo studies in rats were conducted to characterize receptor selectivity and autoreceptor functionality for GT-2016. GT-2016 demonstrated h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::777045529743ae4834ede59cca29f7b2
https://pubmed.ncbi.nlm.nih.gov/7473144
https://pubmed.ncbi.nlm.nih.gov/7473144
Autor:
P G, Dunbar, G J, Durant, T, Rho, B, Ojo, J J, Huzl, D A, Smith, A A, el-Assadi, S, Sbeih, D O, Ngur, S, Periyasamy
Publikováno v:
Journal of medicinal chemistry. 37(17)
Four regioisomers of 2-amino-(methoxycarbonyl)-3,4,5,6-tetrahydropyridine (2a-5a) were synthesized as the racemates to evaluate the utility of exocyclic amidines in the development of novel agonists for M1 muscarinic receptors. Of the four regioisome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1862297bab84ed540e37869d3023bbe3
https://pubmed.ncbi.nlm.nih.gov/8064804
https://pubmed.ncbi.nlm.nih.gov/8064804
Autor:
Ch R Ganellin, K. Burns, D. G. Cooper, David J. Watkin, G. J. Durant, G. S. Sach, C. Bannister, Robert J. Ife, Keith Prout
Publikováno v:
Acta crystallographica. Section B, Structural science. 50
The crystal and molecular structures of ten compounds with strong structural resemblances to the cimetidine group of histamine H2-receptor antagonists, but exhibiting selective H1-receptor antagonist activity, (1)-(7), or H1 and H2 activity (8)-(10),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485396c1eadca30fd9ca50b33d1a7a4c
https://pubmed.ncbi.nlm.nih.gov/7911673
https://pubmed.ncbi.nlm.nih.gov/7911673