Zobrazeno 1 - 10
of 133
pro vyhledávání: '"G. J. Cooper"'
Publikováno v:
The Journal of Physiology. 593:5025-5028
Autor:
Leila Abbas, Stanley J. White, Saeed Hajihashemi, Tracy L. Ware, Tanya T. Whitfield, Tim S. Munsey, G. J. Cooper, Lucy F. Stead
Publikováno v:
The Journal of Physiology. 589:1489-1503
Non-technical summary Due to the conservation of developmental pathways and genetic material over the course of evolution, non-mammalian ‘model organisms’ such as the zebrafish embryo are emerging as valuable tools to explore causes and potential
Publikováno v:
Experimental Physiology. 94:914-927
Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited renal diseases. It is associated with the progressive development of renal tubular cysts, which may subsequently lead to renal failure. Studies into the genetic
Publikováno v:
American Journal of Physiology-Renal Physiology. 296:F642-F648
Facilitative urea transporters in the mammalian kidney play a vital role in the urinary concentrating mechanism. The urea transporters located in the renal inner medullary collecting duct, namely UT-A1 and UT-A3, are acutely regulated by the antidiur
Publikováno v:
Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2006, 453 (1), pp.107-16. ⟨10.1007/s00424-006-0107-0⟩
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2006, 453 (1), pp.107-16. ⟨10.1007/s00424-006-0107-0⟩
TWIK-1, a member of the two-pore domain K(+) channel family, is expressed in brain, kidney, and lung. The aim of this study was to examine the effect of loss of TWIK-1 on the renal cortical collecting duct. Ducts were isolated from wild-type and TWIK
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F1437-F1442
The amphibian urea transporter (fUT) shares many properties with the mammalian urea transporters (UT) derived from UT-A and UT-B genes. The transport of urea by fUT is inhibited by the mercurial agent p-chloromercuribenzenesulfonic acid (pCMBS). We f
Publikováno v:
Journal of Membrane Biology. 211:173-184
K+ channels play an important role in renal collecting duct cell function. The current study examined barium (Ba2+)-sensitive whole-cell K+ currents (IKBa) in mouse isolated collecting duct principal cells. IKBa demonstrated strong inward rectificati
Publikováno v:
American Journal of Physiology-Renal Physiology. 286:F1219-F1225
The early distal tubule (EDT) of the frog nephron, similar to the thick ascending limb in mammals, mediates the transepithelial absorption of NaCl. The continued absorption of NaCl in the face of varying Na+load is maintained by coordination of the a
Autor:
Kyungpyo Park, Craig P. Smith, R. M. Case, Martin C. Steward, G. J. Cooper, Frank Thévenod, P. T. Hurley, E Roussa
Publikováno v:
Archives of Oral Biology. 47:1-9
The human parotid gland secretes much of the bicarbonate that enters the mouth. Prompted by studies of animal models, this study sought evidence for the expression of a functional Na + –HCO 3 − cotransporter (NBC) in human parotid acinar cells. M
Publikováno v:
Journal of Endocrinology. 170:251-257
Adrenomedullin is a 52-amino acid peptide first described in a human phaeochromocytoma but since been found to be present in many tissues, including the vascular system and bone. Because of its structural similarity to amylin and calcitonin gene-rela