Zobrazeno 1 - 10
of 78
pro vyhledávání: '"G. J. Chader"'
Publikováno v:
The Journal of Immunology. 148:2384-2389
Experimental autoimmune uveoretinitis (EAU) in animals is a T cell-mediated autoimmune response directed against cells of the neural retina, in particular the photoreceptors. EAU can be induced in susceptible strains of mice by immunization with puri
Publikováno v:
Current Eye Research. 9:95-98
Interphotoreceptor retinoid-binding protein (IRBP) is a glycoprotein of 1264 residues (bovine) which localizes specifically in the retina and pineal gland and induces inflammatory changes in these organs (EAU and EAP, respectively) in immunized anima
Autor:
J, Lee, X, Jiao, J F, Hejtmancik, M, Kaiser-Kupfer, W A, Gahl, T C, Markello, J, Guo, G J, Chader
Publikováno v:
Investigative ophthalmologyvisual science. 42(8)
To investigate the role of abnormal lipid metabolism in Bietti crystalline dystrophy.Cultured human lymphocytes and fibroblasts from patients with Bietti crystalline dystrophy (BCD) were incubated in the presence of [(14)C]18:3n-3 or [(14)C]18:2n-6.
Publikováno v:
Investigative ophthalmologyvisual science. 42(6)
Heme oxygenase (HO)-1 immunoreactivity (IR) was examined in normal untreated retina and in retinal explants after in vitro treatment with stress agents.Enucleated eyes from young adult C3H mice were immediately fixed and cryosectioned and the retina
Autor:
P, Wong, B A, Pfeffer, S L, Bernstein, M L, Chambers, G J, Chader, Z F, Zakeri, Y Q, Wu, M R, Wilson, S P, Becerra
Publikováno v:
Molecular vision. 6
The clusterin gene encodes a multi-functional protein that has been identified in different tissues, including a number of different eye tissues, primarily in the mouse and to a much lesser extent in humans. Clusterin has been implicated in a number
Publikováno v:
Journal of neuroscience research. 53(1)
We have shown previously that pigment epithelium-derived factor (PEDF) acts as a survival factor for cerebellar granule cell neurons in culture, as well as protecting them against glutamate toxicity. In this study we have examined effects of PEDF on
Publikováno v:
Molecular vision. 4
Pigment epithelium-derived factor (PEDF), a neurotrophic protein, is a member of the serine protease inhibitor supergene family. PEDF promotes both neuronal phenotype in cultured Y79 cells and neuronal survival in cultured cerebellar granulocytes. Th
Publikováno v:
Journal of neuroscience research. 49(6)
Pigment epithelium-derived factor (PEDF), a neurotrophic agent first identified in conditioned medium from cultured human retinal pigment epithelial cells, induces neuronal differentiation with neurite outgrowth in Y-79 retinoblastoma cells and has a
Publikováno v:
International journal of cancer. 72(2)
Deletion of 17p is the most frequent abnormality observed in central nervous system (CNS) primitive neuroectodermal tumors (PNETs), implicating the presence of a tumor suppressor gene which maps to 17p. The gene for pigment epithelium-derived factor