Zobrazeno 1 - 10
of 19
pro vyhledávání: '"G. J. Baldo"'
Autor:
Richard T. Mathias, Steven Bassnett, Christopher Kushmerick, Kulandaiappan Varadaraj, Alan Shiels, G J Baldo
Publikováno v:
Journal of Membrane Biology. 170:191-203
MIP has been hypothesized to be a gap junction protein, a membrane ion channel, a membrane water channel and a facilitator of glycerol transport and metabolism. These possible roles have been indirectly suggested by the localization of MIP in lens ga
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 437:643-651
We have previously shown activation of alpha1-adrenergic receptors increases Na+-K+ pump current (Ip) in guinea pig ventricular myocytes, and the increase is eliminated by blockers of phosphokinase C (PKC). In this study we examined the effect of act
Publikováno v:
Proceedings of the National Academy of Sciences. 95:15303-15308
Fiber cells of the lens are interconnected by an extensive network of gap junctions containing α 3 (Cx46) and α 8 (Cx50) connexins. A specific role for these connexins in lens homeostasis is not known. To determine the contribution of these connexi
Publikováno v:
The Journal of Physiology. 509:117-128
1. The whole-cell patch clamp was employed to study Na+-K+ pump current (Ip) in acutely isolated myocytes. alpha-Adrenergic receptors were activated with noradrenaline (NA) after blocking beta-adrenergic receptors with propranolol. Ip was measured as
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 435:479-484
The beta-agonist isoproterenol (ISO) reduces the Na/K pump current (Ip) via beta-adrenergic receptors when the intracellular calcium concentration ([Ca2+]i) is below 150 nM [8]. In the present study, the intracellular signaling pathway was investigat
Publikováno v:
The Journal of Physiology. 494:697-708
1. The whole cell patch clamp technique was used to study effects of the beta agonist isoprenaline (Iso) on the current-voltage (I-V) relationship of the Na(+)-K+ pump current (Ip) in acutely isolated guinea-pig ventricular myocytes. 2. The effect of
Publikováno v:
Experimental Eye Research. 55:135-144
In patch clamp studies of apical membrane from frog lens epithelium, the most frequently observed channel is ‘stretch-activated’, highly selective for cations over anions but showing little selectivity for Na− vs. K+. In normal physiological sa
Autor:
Ira S. Cohen, Y. Wang, Richard T. Mathias, Junyuan Gao, R. T. Wymore, David McKinnon, G. J. Baldo, Randy S. Wymore, Jane E. Dixon
Publikováno v:
The Journal of physiology. 516
1. Guinea-pig ventricle was used in the RNase protection assays to determine which alpha-isoforms of the Na+-K+ pumps are present, and ventricular myocytes were used in whole cell patch clamp studies to investigate the actions of alpha- and beta-adre
1. The whole-cell patch clamp technique was used to study the effects of acetylcholine (ACh) on Na(+)-K+ pump current (Ip) in acutely isolated guinea-pig ventricular myocytes. Studies were performed in the absence and presence of the beta-agonist iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c246b6d871b260a33143bc14ca6233
https://europepmc.org/articles/PMC1159454/
https://europepmc.org/articles/PMC1159454/
Publikováno v:
The Journal of General Physiology
The whole-cell patch-clamp technique was used to voltage clamp acutely isolated myocytes at -60 mV and study effects of ionic environment on Na/K pump activity. In quiescent guinea pig myocytes, normal intracellular Na+ is approximately 6 mM, which g