Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G. I. Syraeva"'
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 32-44 (2024)
Relevance. Planning the design of bioequivalence clinical studies of generic highly variable drugs requires non-standard approaches – the use of replicative (repeated) or adaptive design. However, both approaches entail an increase in organizationa
Externí odkaz:
https://doaj.org/article/f4fbcc5e5650467f8b66f360ee3fd254
Autor:
V. B. Vasilyuk, M. V. Faraponova, A. B. Verveda, G. I. Syraeva, Yu. B. Vikharev, A. V. Popov, A. L. Kovalenko
Publikováno v:
Российский кардиологический журнал, Vol 29, Iss 8 (2024)
Aim. To study the comparative pharmacokinetics and confirmation of bioequivalence of the generic (T) and original (R) dabigatran etexilate in healthy volunteers after a single oral dose under fasted conditions.Material and methods. To confirm bioequi
Externí odkaz:
https://doaj.org/article/f0d4f2861df44468accf235d3577a562
Publikováno v:
Безопасность и риск фармакотерапии, Vol 12, Iss 1, Pp 24-34 (2024)
SCIENTIFIC RELEVANCE. The safety assessment of investigational medicinal products is a mandatory step in clinical trials of all phases, including bioequivalence studies. However, there are no approaches providing for the individualised assessment of
Externí odkaz:
https://doaj.org/article/27bf444943c848f2af57fa423f3a00f4
Autor:
G. I. Syraeva, V. B. Vasilyuk, A. V. Verveda, M. V. Faraponova, A. S. Kolbin, V. G. Borovskaya
Publikováno v:
Качественная клиническая практика, Vol 0, Iss 4, Pp 73-82 (2023)
Non-steroidal anti-inflammatory drugs are widely used by patients and medical workers, both in the Russian Federation and abroad. Despite the well-established public opinion about the safety of this group of drugs, their use is associated with toxic
Externí odkaz:
https://doaj.org/article/c797d8c511354299bee6ed341b27f170
Autor:
V. B. Vasilyuk, M. V. Faraponova, G. I. Syraeva, A. B. Verveda, A. V. Belskaya, A. V. Shults, L. G. Kubarskaya, E. A. Zolotoverkhaya
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 52-61 (2022)
Relevance. Interpretation of the preclinical trials data is fundamental importance. The correctness of extrapolation of data obtained from animals to humans is due to the qualitative and quantitative diversity of the systems tested the recorded param
Externí odkaz:
https://doaj.org/article/ccade6beb18f43569656c6d7dd4642d8
Publikováno v:
Качественная клиническая практика, Vol 0, Iss 3, Pp 19-30 (2022)
Relevance. Studies devoted to the assessment of consumption, as well as to the issues of pharmacosafety of nonsteroidal anti-inflammatory drugs, are limited at the national level in the Russian Federation. The study of these issues will determine the
Externí odkaz:
https://doaj.org/article/2251cd55ff8e47c8b9cf01c40c9905d3
Autor:
G. I. Syraeva, A. S. Kolbin
Publikováno v:
Качественная клиническая практика, Vol 0, Iss 4, Pp 16-26 (2022)
The group of non-steroidal anti-inflammatory drugs has occupied one of the leading positions in terms of demand by the population over the past decade. This fact is explained by non-prescription sale, a wide range of purposes and an affordable price
Externí odkaz:
https://doaj.org/article/ce606c7316234f649f71ce8001d988ab
Autor:
G. G. Rodionov, I. I. Shantyr, V. B. Vasilyuk, E. A. Kolobova, E. V. Svetkina, M. V. Faraponova, A. B. Verveda, G. I. Syraeva, K. A. Zakharov
Publikováno v:
Качественная клиническая практика, Vol 0, Iss 2, Pp 67-77 (2021)
Fludarabine is a purine antimetabolite with a pronounced immunosuppressive effect. The inhibitory effect of fludarabine depends on its concentration in blood plasma. In addition, the phenotypic characteristics of patients affect the pharmacokinetic a
Externí odkaz:
https://doaj.org/article/dff58a0a93e545279cef1c3e576dfb6a
Publikováno v:
Фармация и фармакология (Пятигорск), Vol 8, Iss 5, Pp 336-344 (2021)
The aim of the review article was to highlight the methodologies for assessing the financial costs of adverse drug reactions exemplified by the Russian Federation and Brazil.Materials and methods: for a comparative analysis, materials from open sourc
Externí odkaz:
https://doaj.org/article/220b2bc2b8224370a873ab0fac3f1d0f