Zobrazeno 1 - 10
of 26
pro vyhledávání: '"G. I. Rodriguez"'
Publikováno v:
Acta Biomedica Scientifica, Vol 3, Iss 2, Pp 35-39 (2018)
The Republic of Cuba is a popular destination for Russian tourists and about 30-50 thousands of Russian citizens visit Cuba annually. However, the recreational activity is often associated with the risk of Ixodid ticks bites and infection with tick-b
Externí odkaz:
https://doaj.org/article/295a5fa4121e4cc5a4abb11b19df045a
Autor:
Suzanne F. Jones, Dieras, Smith L, John A. Hohneker, Eckardt, H. A. Burris, G. I. Rodriguez, Bigley J, Peacock Nw, Hardy J, Von Hoff Dd
Publikováno v:
Investigational New Drugs. 16:37-43
Vinorelbine (Navelbine®) is a unique semi-synthetic vinca-alkaloid with a favorable safety profile that has demonstrated significant antitumor activity in patients with non-small cell lung cancer, advanced breast cancer, advanced ovarian cancer and
Autor:
Sarah A. Taylor, Danika Lew, Roy E. Smith, G. I. Rodriguez, John F. Ensley, David E. Schuller
Publikováno v:
Investigational New Drugs. 14:403-407
Twenty-nine patients with persistent, recurrent and/or metastatic squamous cell carcinoma of the head and neck were treated daily for five days at three-week intervals with topotecan 1.5 mg/m2. Four patients received prior chemotherapy, 23 prior surg
Autor:
H. A. Burris, R. Atsumi, T. Oguma, Leslie Smetzer, J. G. Kuhn, K. Masuo, L. Higashi, D. D. Von Hoff, R. Barrington, Mace L. Rothenberg, K. Sudo, John R. Eckardt, Suzanne M. Fields, G. I. Rodriguez, David Rinaldi, Geoffrey R. Weiss, S. G. Eckhardt
Publikováno v:
Annals of Oncology. 7:491-496
Summary Background Tecogalan sodium is an angiogenesis inhibitor isolated from a sulfated polysaccharide produced by the bacterium Arthrobacter. The antiangiogenic effect of tecogalan sodium is thought to be mediated by the inhibition of binding of b
Autor:
J R Eckardt, David Rinaldi, C DeMoor, C. D. Stephens, D. D. Von Hoff, G. I. Rodriguez, Geoffrey R. Weiss, Don W. Shaffer
Publikováno v:
Anti-Cancer Drugs. 7:402-409
The purpose of this study was to evaluate the feasibility of chronic oral administration of etoposide with granulocyte-macrophage colony-stimulating factor (GM-CSF) [sargramostim (Immunex)] coadministration or premedication; to estimate and compare t
Autor:
Geoffrey R. Weiss, Daniel D. Von Hoff, John R. Eckardt, G. I. Rodriguez, Jinee Rizzo, Howard A. Burris, Lon Smith, Karla VanDenBerg, Suzanne M. Fields, John G. Kuhn
Publikováno v:
Cancer Chemotherapy and Pharmacology. 35:397-402
Preclinical studies of 2-chlorodeoxyadenosine (2-CdA) against solid tumors in the human tumor cloning assay and evidence that 2-CdA is active against slow-growing or resting tumor cells have stimulated interest in the clinical activity of this agent
Autor:
C. A. Denham, Frank M. Balis, K. Havlin, J. B. Craig, D. D. Von Hoff, John G. Kuhn, G. I. Rodriguez, Thomas D. Brown
Publikováno v:
Anti-Cancer Drugs. 4:163-166
Seven adult patients with refractory acute leukemia were administered trimetrexate (TMTX), a non-classical folate antagonist, in a phase I trial. TMTX was administered as an intravenous bolus for five consecutive days at doses of 9-12 mg/m2 based on
Autor:
R. G. Petit, J. G. Kuhn, David Rinaldi, Langdon L. Miller, Lisa A. Hammond, Stephanie Hodges, G. I. Rodriguez, Miguel A. Villalona-Calero, S. G. Eckhardt, D. D. Von Hoff, L. J. Schaaf, Mace L. Rothenberg, Paula K. Locker, Gary Elfring, Abhishek Sharma
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 12(11)
Summary Objectives This trial was performed to determine the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), and pharmacokinetic profile of irinotecan (CPT-11) when administered on a once-every-2-week schedule Patients and methods CPT-11
Autor:
I, Ganly, D, Kirn, G, Eckhardt, G I, Rodriguez, D S, Soutar, R, Otto, A G, Robertson, O, Park, M L, Gulley, C, Heise, D D, Von Hoff, S B, Kaye, S G, Eckhardt
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(3)
An E1B 55 kDa gene-deleted adenovirus, Onyx-015, which reportedly selectively replicates in and lyses p53-deficient cells, was administered by a single intratumoral injection to a total of 22 patients with recurrent head and neck cancer. The objectiv
Autor:
S G, Diab, S D, Baker, A, Joshi, H A, Burris, P W, Cobb, M A, Villalona-Calero, S G, Eckhardt, G R, Weiss, G I, Rodriguez, R, Drengler, M, Kraynak, L, Hammond, M, Finizio, D D, Von Hoff, E K, Rowinsky
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(2)
A Phase I and pharmacological study was performed to evaluate the feasibility, maximum tolerated dose (MTD), dose-limiting toxicities (DLTs), and pharmacokinetics of the anthrapyrazole losoxantrone in combination with paclitaxel in adult patients wit