Zobrazeno 1 - 10
of 13
pro vyhledávání: '"G. I. Gallicano"'
Publikováno v:
Diabetic Medicine. 29:14-23
Type 1 diabetes mellitus--characterized by the permanent destruction of insulin-secreting β-cells--is responsive to cell-based treatments that replace lost β-cell populations. The current gold standard of pancreas transplantation provides only temp
Publikováno v:
Cancer Biomarkers. 3:233-244
The identification of distinct prostate cancer stem cell biomarkers is necessary as researchers attempt to isolate, characterize, and therapeutically target these tumor initiating cells. However, in reading the current literature it is frequently dif
Publikováno v:
Microscopy Research and Technique. 27:134-144
Mammalian oogenesis is a process which requires a variety of changes in the structure and function of the specialized female germ cell. Evidence suggests that the cytoskeleton may mediate several of these structural and functional changes. In this re
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 29(1)
Type 1 diabetes mellitus--characterized by the permanent destruction of insulin-secreting β-cells--is responsive to cell-based treatments that replace lost β-cell populations. The current gold standard of pancreas transplantation provides only temp
Publikováno v:
Cell Motility and the Cytoskeleton. 24:85-99
Mammalian eggs and embryos possess a major cytoskeletal network composed of large planar "sheets" distributed throughout the cytoplasm. Cytoskeletal sheets are found neither in mammalian somatic cells nor in eggs or embryos of non-mammals. In this st
Autor:
Ling Lin, K. Shetty, J. M. Jessup, Rupen Amin, Lopa Mishra, Eric Glasgow, Lynt B. Johnson, Wilma Jogunoori, Aiwu R. He, Michael Zasloff, G. I. Gallicano, John L. Marshall
Publikováno v:
Oncogene. 28(7)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide, with few effective therapeutic options for advanced disease. At least 40% of HCCs are clonal, potentially arising from STAT3+, NANOG+ and OCT3/4+ liver progenitor/s
Publikováno v:
Cell Motility and the Cytoskeleton. 18:143-154
Examination of detergent-extracted mouse eggs and embryos reveals the existence of two cytoskeletal networks. One network is the typical thin filament network observed in somatic cells while the other is composed of large planar elements. These latte
Autor:
G I Gallicano, Kara Foshay
Publikováno v:
Current stem cell researchtherapy. 2(4)
MicroRNAs (miRNAs) are a newly discovered, yet powerful mechanism for regulating protein expression via mRNA translational inhibition. Loss of all miRNA function within mice leads to embryonic lethality with a loss of the stem cell population in the
Publikováno v:
The Journal of Cell Biology
Basonuclin is a zinc finger protein that was thought to be restricted to keratinocytes of stratified squamous epithelia. In epidermis, basonuclin is associated with the nuclei of mitotically active basal cells but not in terminally differentiating ke
Publikováno v:
Molecular reproduction and development. 46(4)
Fertilization of the mammalian egg initiates numerous biochemical and structural changes which remodel the egg into a single-celled zygote. To date, the most extensively studied phenomenon of fertilization in virtually all species has been the relati