Výsledky vyhledávání - "G. I. Deichman"

Alternative production of Bcl-2 and Bax by tumor cells determines the rates of in vivo tumor progression: Suggested mechanisms

Autor: Natalya Dyakova, L. M. Kashkina, V. A. Matveeva, G. I. Deichman

Publikováno v: Journal of Cellular Biochemistry. 101:1148-1164

The hypothesis tested in the study suggests that mechanisms of the earlier described delayed or accelerated tumor progression may be regulated by the antiapoptotic and proapoptotic cellular programs activated in stress reactions of transformed cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48da8f7e7ac1e8dc841dbe9ec907bd14
https://doi.org/10.1002/jcb.21242

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Early phenotypic changes of in vitro transformed cells during in vivo progression: possible role of the host innate immunity

Autor: G. I. Deichman

Publikováno v: Seminars in Cancer Biology. 12:317-326

We described the earliest in vivo changes of in vitro transformed cells of various origin manifested in highly-increased H(2)O(2)-catabolizing and PGE(2)-releasing activities. We designate it as [H(2)O(2)(CA) + PGE(S)]-phenotype. It provided tumor ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99801f75db17236995431045d4c67776
https://doi.org/10.1016/s1044-579x(02)00018-4

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[Untitled]

Autor: N. E. Kushlinsky, G. I. Deichman, S. G. Abbasova, Natalia A. Dyakova, A. V. Pirogov

Publikováno v: Biochemistry (Moscow). 67:240-245

Studies concerning the expression of the receptor CD95 (Fas) by tumor cells and the role of this protein in apoptosis induced by the effector host cells that bear Fas-ligand are mainly focused on the membrane-bound form of Fas. There are only a few d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebc6c1da964a7e0e10dfb0af0377255a
https://doi.org/10.1023/a:1014474316671

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The fingerprints of the host innate immunity on the cells of primary virus-induced tumors

Autor: Lidia Kashkina, E N Uvarova, G. I. Deichman, V. A. Matveeva, Natalya Dyakova

Publikováno v: Immunology Letters. 75:209-214

As shown earlier, the cells transformed in vitro by various oncogenes, during subsequent in vivo growth were gradually replaced by descendant tumor cells, which co-expressed highly increased H 2 O 2 -catabolizing antioxidant activity (H 2 O 2 CA ), a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4aabfcaeeead6f557cf5bffa2c46ac
https://doi.org/10.1016/s0165-2478(00)00304-7

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In vivo acquired mechanisms of tumor cells local defense against the host innate immunity effectors: implication in specific antitumor immunity

Autor: Lidia Kashkina, E N Uvarova, V. A. Matveeva, Natalya Dyakova, G. I. Deichman

Publikováno v: Immunology Letters. 70:37-42

As shown earlier, the cells transformed in vitro by several different oncogenes, or spontaneously, during in vivo growth in normal hosts would be gradually replaced by the highly-tumorigenic descendants co-expressing high H 2 O 2 -catabolizing and PG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b21b23bb4c211771fbb485f84308d3
https://doi.org/10.1016/s0165-2478(99)00123-6

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Cell transforming genes and tumor progression: In vivo unified secondary phenotypic cell changes

Autor: Natalia A. Dyakova, Valentina A. Matveeva, G. I. Deichman, Mikhail A. Nikiforov, L. M. Kashkina, Andrei V. Gudkov, Elvira N. Uvarova

Publikováno v: International Journal of Cancer. 75:277-283

We have earlier shown that Syrian hamster cells spontaneously transformed in vitro during in vivo progression, acquire in I step, along with highly increased tumorigenicity, 2 new properties characterizing the [H 2 O 2 CA + tPGE S ] phenotype, i.e.,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3757663ac669aa3217e6ffb7a5b17812
https://doi.org/10.1002/(sici)1097-0215(19980119)75:2<277::aid-ijc17>3.0.co

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Mechanisms of unusually high antioxidant activity of RSV‐SR‐transformed cells and of its suppression by activated p21 ras

Autor: L. M. Kashkina, Mikhail A. Nikiforov, Andrei Komelkov, Andrei V. Gudkov, Natalia A. Dyakova, Nicolai E. Kushlinsky, Olga Mizenina, A. G. Tatosyan, G. I. Deichman, Marina O. Prilutskaya, Erna G. Gorojanskaya

Publikováno v: International Journal of Cancer. 66:747-752

We have previously demonstrated that hamster embryo fibroblasts (HEFs) transformed by Rous Sarcoma virus, Schmidt-Ruppin strain (RSV-SR) are highly resistant to damage by H 2 O 2 (H 2 O 2 R ), (in contrast to HEFs transformed spontaneously, or by bov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d8653217f07ebb9549b423256ae5434
https://doi.org/10.1002/(sici)1097-0215(19960611)66:6<747::aid-ijc7>3.0.co

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