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Publikováno v:
The Journal of clinical psychiatry. 59
The Clozaril National Registry (CNR) was created to help protect patients from developing potentially fatal agranulocytosis secondary to treatment with the antipsychotic medicine clozapine. The CNR, designed and maintained by the manufacturer of the
Autor:
M G, Choc, F, Hsuan, G, Honigfeld, W T, Robinson, L, Ereshefsky, M L, Crismon, S R, Saklad, J, Hirschowitz, R, Wagner
Publikováno v:
Pharmaceutical research. 7(4)
Clozapine plasma levels were monitored in 16 patients during a series of three consecutive treatments (single dose-multiple dose-single dose). Each patient received a single 75-mg dose (3 x 25 mg) with clozapine tablets, and serial plasma samples wer
Autor:
John E. Overall, Leo E. Hollister, F. Meyer, Eugene M. Caffey, G. Honigfeld, J. L. Bennett, Isham Kimbell
Publikováno v:
Clinical Pharmacology & Therapeutics. 4:200-208
Autor:
G, Honigfeld
Publikováno v:
Psychopharmacology bulletin. 17(4)
Autor:
G, Honigfeld
Publikováno v:
Modern problems of pharmacopsychiatry. 7
Publikováno v:
Pharmaceutical research. 4(5)
After a 2-day buildup, patients were dosed continuously with clozapine solution at three ascending dose levels (37.5, 75, and 150 mg bid for 7 days at each dose level). Following the morning administration on the twenty-third day of dosing a drug hol
Publikováno v:
Journal of clinical psychopharmacology. 7(6)
Clozapine is an atypical antipsychotic drug with reduced risk of unwanted neurological effects in comparison with other drugs. In this multicenter study, 151 hospitalized schizophrenic patients were randomly assigned to treatment under double-blind c
Publikováno v:
Psychopharmacology bulletin. 24(1)
Autor:
G, HONIGFELD
Publikováno v:
Diseases of the nervous system. 25