Zobrazeno 1 - 10
of 28
pro vyhledávání: '"G. Hodson-Walker"'
Autor:
C.G. de Rooij, R.-J. Millischer, R. Ben-Dyke, D.J. Lewis, G.M. Rush, C.J. Hardy, C.H. Farr, G. Hodson-Walker
Publikováno v:
Food and Chemical Toxicology
A battery of in vitro and in vivo tests were conducted on HCFC-141b as a vapour. Bacterial gene mutation assays with Escherichia coli and Salmonella typhimurium were negative in all tester strains. In vitro chromosomal aberration assays were positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b0ee888148a48bcf8e7e2b3db34192
http://europepmc.org/articles/PMC7131127
http://europepmc.org/articles/PMC7131127
Autor:
D.B. Morton, P.A. Botham, R.J. Fielder, D.G. Gatehouse, David Kirkland, D.J. Esdaile, Alan R. Boobis, M. Richold, J.A. Allen, J. Doe, G. Hodson-Walker
Publikováno v:
Scopus-Elsevier
The BTS/UKEMS Working Group was established to consider dose selection for in-vivo mutagenicity assays, and the feasibility of establishing criteria for identifying maximum dose levels that did not involve relating these to a high fraction (50-80%) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb499cc1c5de02ab8cb63a3e706530e9
https://doi.org/10.1177/096032719301200301
https://doi.org/10.1177/096032719301200301
Autor:
D.B. Morton, D.J. Esdaile, P.A. Botham, G. Hodson-Walker, Alan R. Boobis, D.G. Gatehouse, David Kirkland, J.A. Allen, R.J. Fielder, J. Doe, M. Richold
Publikováno v:
Mutagenesis. 7:313-319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d808c98abbe33ee85549faa7f3d6e484
https://doi.org/10.1093/mutage/7.5.313
https://doi.org/10.1093/mutage/7.5.313
Publikováno v:
Toxicology Letters. 74:96-97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbfa82e8bce895d018c0257bf7bdbbe5
https://doi.org/10.1016/0378-4274(94)90474-x
https://doi.org/10.1016/0378-4274(94)90474-x
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 153:57-77
41 compounds or mixtures of diverse structure and application have been tested for genotoxic activity. The materials were tested in bacterial mutation assays, in Saccharomyces cerevisiae JD1 for mitotic gene conversion and in a cultured rat-liver cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77d9b825a1c22b4626193c5e01faf89
https://doi.org/10.1016/0165-1110(85)90005-3
https://doi.org/10.1016/0165-1110(85)90005-3
Autor:
G. Hodson-Walker, B.J. Dean
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 64:329-337
An in vitro chromosome assay has been developed which utilises an epithelial-like cell line derived from rat liver. The cell line, designed RL 1 , retains sufficient metabolic enzyme activity to detect chromosome damage induced by a variety of chemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8686f62a84ca3535d384ec09d96a97ec
https://doi.org/10.1016/0165-1161(79)90125-0
https://doi.org/10.1016/0165-1161(79)90125-0
Autor:
B.J. Dean, G. Hodson-Walker
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 64:407-413
Good qualitative correlations between mutation in bacteria and carcinogenic effects in laboratory animals have been shown by a number of workers. As a result, in vitro microbial mutation assays are now widely used in a preliminary screen for detectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001c7a3e104ae0358a65e9d494007097
https://doi.org/10.1016/0165-1161(79)90110-9
https://doi.org/10.1016/0165-1161(79)90110-9
Publikováno v:
Archives of Toxicology ISBN: 9783540093053
In order to investigate the relationship between mutation and carcinogenesis in vivo, a method has been developed in which somatic mutation can be studied in specific organs of Chinese hamsters after acute dosing with chemical carcinogens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3edea4d9e79009cdb1b936a28d8e1b55
https://doi.org/10.1007/978-3-642-67265-1_24
https://doi.org/10.1007/978-3-642-67265-1_24
Publikováno v:
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. (2)
In order to investigate the relationship between mutation and carcinogenesis in vivo, a method has been developed in which somatic mutation can be studied in specific organs of Chinese hamsters after acute dosing with chemical carcinogens. In prelimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cd0a5c0fc03df798127db487357236d
https://pubmed.ncbi.nlm.nih.gov/223525
https://pubmed.ncbi.nlm.nih.gov/223525
Publikováno v:
Mutation research. 100(1-4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58022574ab22e50a7af060e9a4e0cd6c
https://pubmed.ncbi.nlm.nih.gov/7057761
https://pubmed.ncbi.nlm.nih.gov/7057761