Zobrazeno 1 - 10
of 155
pro vyhledávání: '"G. Harkin"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Microglia play crucial roles in immune responses and contribute to fundamental biological processes within the central nervous system (CNS). In neurodegenerative diseases, microglia undergo functional changes and can have both protective and pathogen
Externí odkaz:
https://doaj.org/article/cce4b4ffc8aa4e5581eefb2ec4e26f4b
Autor:
Elham Nili, Damien G. Harkin, Rebecca A. Dawson, Neil A. Richardson, Shuko Suzuki, Traian V. Chirila
Publikováno v:
Molecules, Vol 26, Iss 22, p 6810 (2021)
A recombinant formulation of silk fibroin containing the arginine–glycine–aspartic acid (RGD) cell-binding motif (RGD-fibroin) offers potential advantages for the cultivation of corneal cells. Thus, we investigated the growth of corneal stromal c
Externí odkaz:
https://doaj.org/article/3dc00f7b878540eb8831d5ada83229c6
Autor:
Elham Nili, Fiona J. Li, Rebecca A. Dawson, Cora Lau, Blair McEwan, Nigel L. Barnett, Steven Weier, Jennifer Walshe, Neil A. Richardson, Damien G. Harkin
Publikováno v:
Cell Transplantation, Vol 28 (2019)
While limbal epithelial cells are used for treating ocular surface wounds, the therapeutic potential of mesenchymal cells cultivated from the limbal stroma (LMSC) is less clear. We have therefore examined the effects of LMSC when applied to acute ocu
Externí odkaz:
https://doaj.org/article/692e48b9392c4a85b80680817beb57cd
Publikováno v:
Tissue Engineering Part B: Reviews. 28:555-568
Rho-associated protein kinases (ROCKs) affect a variety of cellular functions, including cell attachment, migration, and proliferation. ROCK inhibitors therefore have potential as tools for optimizing cell behavior in tissue engineering applications,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fd64b3e3d61941d6391c5164c7b120
https://doi.org/10.1089/ten.teb.2021.0034
https://doi.org/10.1089/ten.teb.2021.0034
Autor:
Audra M. A. Shadforth, Shuko Suzuki, Raphaelle Alzonne, Grant A. Edwards, Neil A. Richardson, Traian V. Chirila, Damien G. Harkin
Publikováno v:
Journal of Functional Biomaterials, Vol 6, Iss 3, Pp 946-962 (2015)
Bombyx mori silk fibroin membranes provide a potential delivery vehicle for both cells and extracellular matrix (ECM) components into diseased or injured tissues. We have previously demonstrated the feasibility of growing retinal pigment epithelial c
Externí odkaz:
https://doaj.org/article/1b86aab778dc41a8a7b4cd4b3a74d53a
Autor:
Shuko Suzuki, Rebecca A. Dawson, Traian V. Chirila, Audra M. A. Shadforth, Thomas A. Hogerheyde, Grant A. Edwards, Damien G. Harkin
Publikováno v:
Journal of Functional Biomaterials, Vol 6, Iss 2, Pp 345-366 (2015)
A silk protein, fibroin, was isolated from the cocoons of the domesticated silkworm (Bombyx mori) and cast into membranes to serve as freestanding templates for tissue-engineered corneal cell constructs to be used in ocular surface reconstruction. In
Externí odkaz:
https://doaj.org/article/97842684f95f4768ac21f5a56ab07871
Autor:
Damien G. Harkin, Siobhan E. Dunphy, Audra M. A. Shadforth, Rebecca A. Dawson, Jennifer Walshe, Nadia Zakaria
Publikováno v:
Cell Transplantation, Vol 26 (2017)
When used as scaffolds for cell therapies, biomaterials often present basic handling and logistical problems for scientists and surgeons alike. The quest for an appropriate mounting device for biomaterials is therefore a significant and common proble
Externí odkaz:
https://doaj.org/article/ff6ae815c00840b69616bdf294a54143
Publikováno v:
Journal of Functional Biomaterials, Vol 4, Iss 2, Pp 74-88 (2013)
While fibroin isolated from the cocoons of domesticated silkworm Bombyx mori supports growth of human corneal limbal epithelial (HLE) cells, the mechanism of cell attachment remains unclear. In the present study we sought to enhance the attachment of
Externí odkaz:
https://doaj.org/article/51bde41f39be4a88ac108b28a4f876b1
Autor:
Thomas A. Hogerheyde, Shuko Suzuki, Jennifer Walshe, Laura J. Bray, Sally A. Stephenson, Damien G. Harkin, Neil A. Richardson
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Scaffolds prepared from silk fibroin derived from cocoons of the domesticated silkworm moth Bombyx mori have demonstrated potential to support the attachment and growth of human limbal epithelial (HLE) cells in vitro. In this study, we attempted to f
Externí odkaz:
https://doaj.org/article/a24549a5d2cb45d1b4713f70c9b21d39
Autor:
Traian V. Chirila, Neil A. Richardson, Damien G. Harkin, Elham Nili, Rebecca A. Dawson, Shuko Suzuki
Publikováno v:
Molecules
Volume 26
Issue 22
Molecules, Vol 26, Iss 6810, p 6810 (2021)
Volume 26
Issue 22
Molecules, Vol 26, Iss 6810, p 6810 (2021)
A recombinant formulation of silk fibroin containing the arginine–glycine–aspartic acid (RGD) cell-binding motif (RGD-fibroin) offers potential advantages for the cultivation of corneal cells. Thus, we investigated the growth of corneal stromal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5273328a8bd4e938f58833e5eb26312c