Zobrazeno 1 - 10
of 28
pro vyhledávání: '"G. Hards"'
Publikováno v:
Nutrition Research. 18:1175-1186
Quantitation of β-casein was achieved through the use of urea-polyacrylamide gel electrophoresis of whole milk and scanning densitometry. This method also provided electrophorectic separation of the different phosphoforms of β-casein which were als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0b65b39ee26ba45a9270c46c1860bf1
https://doi.org/10.1016/s0271-5317(98)00098-0
https://doi.org/10.1016/s0271-5317(98)00098-0
Autor:
B C Xu, John J. Kopchick, Pradip Mukerji, C T Seipelt, R G Hards, M Byström, M Strömqvist, L Hansson, A.E. Leonard, J.M. Thurmond, Kerstin Enquist
Publikováno v:
Protein Expression and Purification. 10:202-208
Specific serine and threonine residues of recombinant human beta-casein produced in Escherichia coli were shown to be phosphorylated in vivo when human casein kinase II was coexpressed in the same plasmid. All of the phosphorylated forms found in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccef02be5ac099a41541b57bb4f8176b
https://doi.org/10.1006/prep.1997.0737
https://doi.org/10.1006/prep.1997.0737
Autor:
C. Jaffray, G. Hards
Publikováno v:
Handbook of Fuel Cells
Two scenarios for the growth of the transportation market for proton exchange membrane (PEM) fuel cell engines have been developed. A continuing growth in the global vehicle population and a continuing technological development to reduce platinum loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42924dd31bd9a78e661921c2f3bd0bd1
https://doi.org/10.1002/9780470974001.f303045
https://doi.org/10.1002/9780470974001.f303045
Publikováno v:
Biological Psychiatry. 28:1058-1060
As GARS activity has been shown to be a sensitive measure for chromosome 21, we have compared its activity in lymphocytes from patients with AD to that of normal controls, to detemine whether a dosage effect exists in AD. Increased activity would sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79f2344d41b9a1832ec186c7bcb0ac7
https://doi.org/10.1016/0006-3223(90)90607-4
https://doi.org/10.1016/0006-3223(90)90607-4
Autor:
David Patterson, Robert G. Hards
Publikováno v:
Journal of Chromatography A. 455:217-224
An ion-pair reversed-phase high-performance liquid chromatographic procedure capable of resolving twelve of the fourteen intermediates of de novo purine biosynthesis is presented. The method utilizes isocratic elution and detection by ultraviolet lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68bd3699d67c1092bfe448248cb00bd
https://doi.org/10.1016/s0021-9673(01)82120-8
https://doi.org/10.1016/s0021-9673(01)82120-8
Autor:
Robert G. Hards, Jim A. Wright
Publikováno v:
Canadian Journal of Biochemistry and Cell Biology. 61:120-129
N-Carbamoyloxyurea is cytotoxic for cells in culture and, like hydroxyurea and guanazole, the drug is an effective inhibitor of mammalian ribonucleotide reductase and thus DNA synthesis. In addition to ribonucleotide reductase, N-carbamoyloxyurea has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bdbf790ae1a82e7916a326f92b0303
https://doi.org/10.1139/o83-018
https://doi.org/10.1139/o83-018
Publikováno v:
Advances in Enzyme Regulation. 19:105-127
We are using a genetic approach to study the complex properties of mammalian ribonucleotide reductase activity. Cytotoxic drugs (hydroxyurea, guanzole and N-carbamoyloxyurea) whose intracellular site of action is ribnonucleotide reductase have been u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a343a8ad128ccb76e089675ba0309fe0
https://doi.org/10.1016/0065-2571(81)90011-x
https://doi.org/10.1016/0065-2571(81)90011-x
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 28:480-483
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bb7b40c392108dbfc8bf679c08d851
https://doi.org/10.1007/bf01607715
https://doi.org/10.1007/bf01607715
Autor:
Jim A. Wright, Robert G. Hards
Publikováno v:
Journal of Cellular Physiology. 106:309-319
We describe the isolation and characterization of a Chinese hamster ovary cell line selected for resistance to N-carbamoyloxyurea. Using the mammalian cell permeabilization assay developed in our laboratory, a detailed analysis of the target enzyme,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad80420e5bac28b06608d62a675ccf9
https://doi.org/10.1002/jcp.1041060218
https://doi.org/10.1002/jcp.1041060218
Autor:
Robert G. Hards, David Patterson
Publikováno v:
Mechanisms of Ageing and Development. 36:65-70
The levels of glycinamide ribonucleotide synthetase were monitored in four human fibroblast cell lines, two diploid, one monosomy 21 and one trisomy 21, from early passage number to senescence. In all four lines, enzyme activity increased as the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61dec1b7f2c32b6f1de46207ddbfd74
https://doi.org/10.1016/0047-6374(86)90139-9
https://doi.org/10.1016/0047-6374(86)90139-9