Zobrazeno 1 - 10
of 181
pro vyhledávání: '"G. H. Guyatt"'
Autor:
S. D. Walter, H. Han, G. H. Guyatt, D. Bassler, N. Bhatnagar, V. Gloy, S. Schandelmaier, M. Briel
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Randomised trial protocols may incorporate interim analyses, with the potential to stop the study for futility if early data show insufficient promise of a treatment benefit. Previously, we have shown that this approach will theor
Externí odkaz:
https://doaj.org/article/39d9feb828794f3284cf6f23a43597cc
Publikováno v:
Statistics in Medicine. 38:2524-2543
Stopping rules for clinical trials are primarily intended to control Type I error rates if interim analyses are planned, but less is known about the impact that potential stopping has on estimating treatment benefit. In this paper, we derive analytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c141478c43c56e192a1c154d66ecf9
https://doi.org/10.1002/sim.8142
https://doi.org/10.1002/sim.8142
Autor:
G. H. Guyatt, Claudia Valli, Bradley C. Johnston, Pablo Alonso-Coello, R. El Dib, Dena Zeraatkar, Mi Ah Han, Malgorzata M Bala, Rwm Vernooij
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3134a4297097cf5b19ac4515555bda4a
https://ruj.uj.edu.pl/xmlui/handle/item/284120
https://ruj.uj.edu.pl/xmlui/handle/item/284120
Autor:
G. H. Guyatt, Neera Bhatnagar, Matthias Briel, H D Han, Stefan Schandelmaier, Dirk Bassler, Viktoria Gloy, Stephen D. Walter
Publikováno v:
BMC Medical Research Methodology
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-11 (2020)
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-11 (2020)
Background Randomised trial protocols may incorporate interim analyses, with the potential to stop the study for futility if early data show insufficient promise of a treatment benefit. Previously, we have shown that this approach will theoretically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080a1c470e7a4d8d980a0b6047bf604f
http://europepmc.org/articles/PMC6966801
http://europepmc.org/articles/PMC6966801
Autor:
O. Baron, Ana C. Alba, A. Marichev, Heather J. Ross, G. H. Guyatt, M. Simonenko, Ugolino Livi, Natasha Aleksova, Michael Mastroianni, Ani Orchanian-Cheff, A. Zhu, K. Jawad, Sandro Sponga, M. Pozzi, Farid Foroutan, Silvana Marasco, Pierre-Emmanuel Noly, D.O. Absi, E. Dal Checco, Tayler A. Buchan, A. Defontaine, S. Lehmann, Masashi Kawabori, Antonino Loforte, Michel Carrier, F. Billia
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S85-S86
Purpose Early graft dysfunction (EGD) is a major cause of morbidity and mortality following heart transplantation (HT). The rate of severe EGD requiring inotropes and/or mechanical circulatory support such as veno-arterial extracorporeal membrane oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e90ce93b5f7fdfba2f8084c424eb1cc
https://doi.org/10.1016/j.healun.2021.01.1948
https://doi.org/10.1016/j.healun.2021.01.1948
Mortality outcomes in patients transfused with fresher versus older red blood cells: a meta-analysis
Autor:
David Roxby, Chatree Chai-Adisaksopha, Philip J. Devereaux, John W. Eikelboom, G. H. Guyatt, Nancy M. Heddle, Paul E. Alexander, Martin Ellis, D. I. Sessler, Mark Crowther
Publikováno v:
Vox Sanguinis. 112:268-278
Background Among transfused patients, the effect of the duration of red blood cell storage on mortality remains unclear. This study aims to compare the mortality of patients who were transfused with fresher versus older red blood cells. Methods We pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14bb81ba5ae156ededb250c9a6ba1ef
https://doi.org/10.1111/vox.12495
https://doi.org/10.1111/vox.12495
Publikováno v:
Statistics in Medicine. 36:1506-1518
In this paper, we consider the potential bias in the estimated treatment effect obtained from clinical trials, the protocols of which include the possibility of interim analyses and an early termination of the study for reasons of futility. In partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b22b479cd2b3e0a4358b2731349e31b
https://doi.org/10.1002/sim.7242
https://doi.org/10.1002/sim.7242
Autor:
G. H. Guyatt, Omid Kiamanesh, Sharon Chih, H.J. Ross, N. Aleksova, J. Petropoulos, Y. Chang, D. Brahmbhatt
Publikováno v:
Canadian Journal of Cardiology. 36:S75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f9d494e8eba35fc6cec6fb32d5b44f
https://doi.org/10.1016/j.cjca.2020.07.149
https://doi.org/10.1016/j.cjca.2020.07.149
Autor:
Emil H. Schemitsch, Sheila Sprague, G. H. Guyatt, Brad Petrisor, Stephen D. Walter, Paula McKay, Susan Liew, Kyle J. Jeray, Mohit Bhandari, Diane Heels-Ansdell
Publikováno v:
Bone and Joint Institute
The Bone & Joint Journal
The Bone & Joint Journal
Aims The Fluid Lavage in Open Fracture Wounds (FLOW) trial was a multicentre, blinded, randomized controlled trial that used a 2 × 3 factorial design to evaluate the effect of irrigation solution (soap versus normal saline) and irrigation pressure (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c3409bf1050ef60d23cea4e59750e8
https://ir.lib.uwo.ca/context/boneandjointpub/article/2177/viewcontent/wound_irrigation_does_not_affect.pdf
https://ir.lib.uwo.ca/context/boneandjointpub/article/2177/viewcontent/wound_irrigation_does_not_affect.pdf
Autor:
Abdullah Almulhim, Lawrence Mbuagbaw, G. H. Guyatt, Amal H AlSulaibikh, Waleed Alhazzani, Muhammed Alshahrani, M.M. ElTahan, Sukayna Alfaraj, Mohammed Al-Jumaan, Nisreen Almaghraby, L. Perlas Asonto
Publikováno v:
Annals of Emergency Medicine. 74:S89-S90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981fa6f9e2ce9bbaca1b7a578926edf4
https://doi.org/10.1016/j.annemergmed.2019.08.394
https://doi.org/10.1016/j.annemergmed.2019.08.394