Zobrazeno 1 - 10
of 216
pro vyhledávání: '"G. H. Gurtner"'
Autor:
G. H. Gurtner, T. Burke-Wolin
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 260:L207-L211
Oxidants have complex effects on pulmonary vascular reactivity. They can stimulate production of vasoconstrictor arachidonate mediators and can also cause vasodilation through activation of guanylate cyclase. Oxidants can also inactivate vasomotor ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2568117506959ea515ed5c6689aaa6
https://doi.org/10.1152/ajplung.1991.260.4.l207
https://doi.org/10.1152/ajplung.1991.260.4.l207
Autor:
A. M. Sciuto, Yueliang Leon Guo, John R. Michael, T. P. Kennedy, N. F. Adkinson, G. H. Gurtner, A. J. Ghio
Publikováno v:
Journal of Applied Physiology. 69:1615-1622
We have previously shown that phosgene markedly increases lung weight gain and pulmonary vascular permeability in rabbits. The current experiments were designed to determine whether cyclooxygenase- and lipoxygenase-derived mediators contribute to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3774abf7cbb0ce8fb8338bbd3c19432f
https://doi.org/10.1152/jappl.1990.69.5.1615
https://doi.org/10.1152/jappl.1990.69.5.1615
Publikováno v:
Journal of applied toxicology : JAT. 18(5)
This study investigated the post-treatment effect of isoproterenol (ISO) on pulmonary parameters in rabbits whole-body-exposed to a lethal dose of the toxic gas phosgene. Phosgene is widely used in industry as a chemical intermediate for the producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc9185a76f71ea7eb0916caab9583a1f
https://pubmed.ncbi.nlm.nih.gov/9804432
https://pubmed.ncbi.nlm.nih.gov/9804432
Publikováno v:
Advances in experimental medicine and biology. 407
We have previously found that 5,6-EET (epoxyeicosatrienoic acid)(50 nM) significantly dilates the vascular bed(42%) of the isolated, constantly perfused rabbit lung, which has been constricted with U46619(5-8 pM). We studied the role of EDRF-NO and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c4e292882d1895fea2ea1a57e1d3da7
https://pubmed.ncbi.nlm.nih.gov/9322008
https://pubmed.ncbi.nlm.nih.gov/9322008
Publikováno v:
Vascular Endothelium ISBN: 9781461380139
We are interested in the actions of arachidonic acid and NO mediators on the pulmonary circulation. AA mediators can directly cause vasoconstriction or dilatation and peptide leukotrienes can directly cause increased permeability. There appear to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a5cc9e459ba830224f1da407283cf7
https://doi.org/10.1007/978-1-4613-0355-8_42
https://doi.org/10.1007/978-1-4613-0355-8_42
Autor:
John R. Michael, Sajal Chakraborti, A. Merker, G. H. Gurtner, Siddhartha Sankar Ghosh, G. Dutta
Publikováno v:
The Biochemical journal. 292
Exposure of bovine pulmonary-arterial endothelial cells to the oxidant lipid t-butyl hydroperoxide (t-Bu-OOH) increases cell-membrane-associated phospholipase A2 (PLA2) activity and stimulates arachidonic acid (AA) release. To test the hypothesis tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b2fbbcbf6d4cbd7aca4ef608a7658a
https://pubmed.ncbi.nlm.nih.gov/8503892
https://pubmed.ncbi.nlm.nih.gov/8503892
Publikováno v:
The American journal of physiology. 261(6 Pt 1)
Hydrogen peroxide (H2O2), but not tertbutyl hydroperoxide, produces a concentration-dependent vasodilation of the pulmonary circulation in isolated saline perfused rabbit lungs when pulmonary arterial pressures (PAP) are raised with the thromboxane a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3540bed8f53a52032b6a7aa079d0db3f
https://pubmed.ncbi.nlm.nih.gov/1662918
https://pubmed.ncbi.nlm.nih.gov/1662918
Autor:
G. H. Gurtner, R. J. Traystman
Publikováno v:
Journal of Applied Physiology. 47:67-71
Five anesthetized dogs were made severely hypercapnic by stepwise addition of CO2 to their inspired air. Blood PCO2 levels greater than 400 Torr were reached. During hypercapnia, the steady-state end-tidal PCO2 (PaCO2) was always higher than the simu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78edb09132e1a79bc68226efc51eb2ad
https://doi.org/10.1152/jappl.1979.47.1.67
https://doi.org/10.1152/jappl.1979.47.1.67
Publikováno v:
Journal of Applied Physiology. 53:505-509
Steady-state CO pulmonary diffusing capacity (DLCO) was measured at different inspired CO concentrations in seven males and one female during light treadmill exercise. As the CO level is increased. DLCO increases, reaches a maximum at an end-tidal CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd905cf8a08ae2d78951184cb9ad8a7
https://doi.org/10.1152/jappl.1982.53.2.505
https://doi.org/10.1152/jappl.1982.53.2.505