Zobrazeno 1 - 10
of 29
pro vyhledávání: '"G. H. Draffan"'
Publikováno v:
Journal of Chromatography A. 139:311-320
The gas chromatographic (GC) determination of the herbicide paraquat, the 1,1'-dimethyl-4,4'-dipyridyl cation in human plasma is described. In poisoning cases, plasma concentrations provide a necessary index of the severity of intoxication and a mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda80f838319783685fe8d19cbe35262
https://doi.org/10.1016/s0021-9673(00)89326-7
https://doi.org/10.1016/s0021-9673(00)89326-7
Publikováno v:
Journal of Pharmacy and Pharmacology. 26:175-178
After single 200 mg oral doses of butobarbitone (I) in man, 5·4% was excreted in urine unchanged and 28·2% as the 3î-hydroxy metabolite (II) in six days. A new metabolite, the ketone (III), was detected in urine following oral administration both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5840f27cd1ef6ee009816d47e34cd7
https://doi.org/10.1111/j.2042-7158.1974.tb09250.x
https://doi.org/10.1111/j.2042-7158.1974.tb09250.x
Publikováno v:
Biochemical Medicine. 16:77-94
An improved gc-ms method has been developed for the measurement of 5α,7α- dihydroxy - 11 - ketotetranorprosta - 1,16 - dioic acid (PGF-M), the major urinary metabolite of PGF1α and PGF2α in man. The assay is based on gas chromatography and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b310f11de6a545b551c8e664a90b75fe
https://doi.org/10.1016/0006-2944(76)90011-9
https://doi.org/10.1016/0006-2944(76)90011-9
Publikováno v:
Thorax. 29:99-103
Williams, Faith M., Draffan, G. H., Dollery, C. T., Clark, J. C., Palmer, A. J., and Vernon, P. (1974). Thorax , 29 , 99-103. Use of 18 F labelled fluorocarbon-11 to investigate the fate of inhaled fluorocarbons in man and in the rat. The distributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b47a0259d9bef35a4aaa8a5ac7dac70
https://doi.org/10.1136/thx.29.1.99
https://doi.org/10.1136/thx.29.1.99
Publikováno v:
Xenobiotica. 4:237-254
1. After administration of [14C]phenylbutazone by stomach tube to rats 1/3 of the radioactivity was excreted in the faeces and almost 2/3 in the urine over 48 h. Biliary excretion after intraperitoneal injection was slightly more than 1/3 of the dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211a6c53fd0f8ec240d89e521e29d1f9
https://doi.org/10.3109/00498257409062542
https://doi.org/10.3109/00498257409062542
Autor:
C. R. Dean, Donald S. Davies, R. A. Clare, Stephen Murray, H. J. Dargie, J. L. Reid, Colin T. Dollery, G. H. Draffan
Publikováno v:
Clinical Pharmacology & Therapeutics. 19:11-17
A 300-mug oral dose of clonidine was administered to 5 normal volunteers and measurements of plasma concentration and effects upon blood pressure, heart rate, circulatory reflexes, sedation, and dry mouth were made for the following 8 hr. The plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676538e89eaef1c8f5170fcc432359cc
https://doi.org/10.1002/cpt197619111
https://doi.org/10.1002/cpt197619111
Publikováno v:
Chemical Geology. 8:277-297
Thermal treatment of 4-14C-cholesterol incorporated in pulverised Green River Shale (Eocene) resulted in the formation of a number of 14C radiolabelled hydrocarbons. Major products were labelled cholest-4-ene and labelled cholest-5-ene. These were pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c03a6f597ac3ca09d5fef4e1d7e412b
https://doi.org/10.1016/0009-2541(71)90022-2
https://doi.org/10.1016/0009-2541(71)90022-2
Publikováno v:
Journal of Chromatography A. 75:45-53
Techniques for the measurement of amylobarbitone and its pricipal metabolite, 3′-hydroxyamylobarbitone in 100-μl plasma samples are described. The methods which employ a mass spectrometer as a gas chromatographic detector may be used to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3954227ee3dbd0054eec1beb9969c6
https://doi.org/10.1016/s0021-9673(01)83412-9
https://doi.org/10.1016/s0021-9673(01)83412-9
Publikováno v:
Life Sciences. 10:1243-1251
Following the intraperitoneal administration of L-3-O-14C-methyl-4-hydroxyphenylalanine (14C-3- o -methyldopa; 14C- O MD), to rats, 15–20% of the injected radioactivity appeared in the expired air as 14C-CO2 over a period of 3–4 days; 65% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80588d51d6aea156315f4f1d203a75fb
https://doi.org/10.1016/0024-3205(71)90294-3
https://doi.org/10.1016/0024-3205(71)90294-3
Publikováno v:
Organic Mass Spectrometry. 1:669-685
Mass spectra of trimethylsilyl (TMS) derivatives of long chain dicarboxylic acids, hydroxy acids, cyano acids, and terminal diols, dithiols and diamines have been examined. A number of fragmentation pathways involving rearrangement of partial or inta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31ffc8eb8fca876337013e35f8531f74
https://doi.org/10.1002/oms.1210010508
https://doi.org/10.1002/oms.1210010508