Zobrazeno 1 - 10
of 92
pro vyhledávání: '"G. Goldberger"'
Publikováno v:
Journal of Dental Research. 70:95-98
Xenopus laevis oocytes injected with poly (A+) RNA isolated from rat parotid and submandibular glands synthesize and secrete salivary proteins. Amylase was identified in the media of cultured oocytes injected with rat parotid mRNA by size and immunop
Publikováno v:
Nephrology newsissues. 12
Tissue-specific pretranslational regulation of complement production in human mononuclear phagocytes
Publikováno v:
The Journal of Immunology. 134:2610-2616
The net production of the complement protein C2, C4, and factor B differ among mononuclear phagocytes from peripheral blood and different tissues in experimental animals and in humans. To examine the mechanisms that regulate these differences in huma
Publikováno v:
The Journal of Immunology. 138:3967-3971
Inflammation or acute tissue injury results in a programmed change in the concentration of several plasma proteins. Among these proteins, two--C-reactive protein (CRP) and serum amyloid A protein (SAA)--increase up to 1000-fold after an acute-phase s
Autor:
Jan L. Breslow, Sotirios K. Karathanasis, Henry T. Keutmann, Vassilis I. Zannis, G Goldberger
Publikováno v:
Proceedings of the National Academy of Sciences. 80:2574-2578
We have recently proposed that the major secreted isoprotein form of human apolipoprotein A-I (designated apo A-I2) is modified extracellularly to become the predominant apo A-I form seen in plasma (designated apo A-I4). In the current report we demo
Publikováno v:
The Journal of Immunology. 129:2061-2065
In order to characterize a genetic deficiency of C2 in guinea pigs, production of C2 by peritoneal macrophage cultures derived from four normal, four heterozygous deficient, and four homozygous deficient animals was measured functionally and immunoch
Publikováno v:
Scopus-Elsevier
Human factor I is a two-chain plasma glycoprotein composed of disulfide-linked 50,000- and 38,000-dalton subunits. Analysis of its biosynthesis and postsynthetic processing demonstrated that factor I is synthesized as a single chain precursor (pro-I)
Publikováno v:
Journal of Biological Chemistry. 259:10380-10385
The second component of complement (C2), is a class III major histocompatibility complex gene product and a glycoprotein in the classical complement activating system. Synthesis in the human hepatoma-derived cell line HepG2 results in three intracell
Publikováno v:
Biochemical Journal. 204:839-846
Tunicamycin, an inhibitor of N-acetylglucosaminylpyrophosphopolyisoprenol-dependent glycosylation, was used to study the effect of glycosylation on the synthesis, post-translational modification, secretion and function of the complement proteins that
Publikováno v:
Journal of Biological Chemistry. 262:10065-10071
Factor I is a serine proteinase of complement which together with one of several specific cofactors cleaves activation products of the third and fourth components of complement (C3b and C4b) and modulates the activity of C3 convertase. A heterodimer