Zobrazeno 1 - 10
of 122
pro vyhledávání: '"G. Godeheu"'
Autor:
Yvette Torrens, Sandra Jimena Hernández Vallejo, Jean-Pol Tassin, Emilie Lucie Doucet, Vanessa Houades, G. Godeheu, Christophe Lanteri, Lucas Salomon
Publikováno v:
The Journal of Neuroscience. 29:987-997
Although nicotine is generally considered to be the main compound responsible for addictive properties of tobacco, experimental data indicate that nicotine does not exhibit all the characteristics of other substances of abuse. We recently showed that
Publikováno v:
Journal of Neurochemistry. 64:1406-1409
Arachidonic acid (AA) markedly stimulated, in a dose-dependent manner, the spontaneous release of [3H]dopamine ([3H]DA) continuously synthesized from [3H]tyrosine in purified synaptosomes from the rat striatum. As estimated by simultaneous measuremen
Publikováno v:
European Journal of Neuroscience. 11:1292-1300
Arachidonic acid stimulated the release of [3H]-dopamine from striatal microdiscs in a concentration-dependent and partially calcium-dependent manner. Inhibitors of cytosolic and membrane-bound phospholipase A2 were used to determine whether endogeno
Publikováno v:
Brain Research. 792:253-262
Mouse purified striatal synaptosomes were used to study the release of newly synthesised [3H]-dopamine ([3H]-DA) or of previously taken up [3H]-DA. Quinpirole (QP, 10 microM), a D2/D3 dopaminergic agonist, was found to reduce the release of newly syn
Publikováno v:
Amino Acids. 14:63-68
Dopamine (DA) release from nerve terminals of the nigrostriatal DA neurons not only depends on the activity of nigral DA cells but also on presynaptic regulation. Glutamatergic neurons of cortical origin play a prominent role in these presynaptic reg
Publikováno v:
Neurochemistry International. 25:145-154
Purified striatal synaptosomes were continuously superfused with l ,3,5[3H]tyrosine in order to estimate the synthesis ([3H]water) and release of newly formed [3H]dopamine. In the presence of magnesium, l -glutamate, d , l -α-amino-3-hydroxy-5-methy
Publikováno v:
Brain Research. 640:205-214
Purified striatal synaptosomes were superfused continuously with L-[3,5-3H]tyrosine to measure simultaneously the synthesis ([3H]water formed during the conversion of [3H]tyrosine into [3H]DOPA) and the release of [3H]dopamine ([3H]DA). Glutamate (10
Publikováno v:
Neuroscience. 47:333-339
Previously, using purified synaptosomes from the rat striatum, we have shown that agonists of D,L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors stimulate the release of [3H]dopamine continuously synthesized from [3H]tyrosine.
Autor:
G. Godeheu, Jacques Glowinski, J. M. Desce, M.L. Kemel, Marie-Odile Krebs, André Chéramy, C. Gauchy
Publikováno v:
Journal of Neurochemistry. 56:81-85
The N-methyl-D-aspartate (NMDA) receptor-mediated regulation of the release of newly synthesized [3H]dopamine [( 3H]DA) was studied in vitro, both on rat striatal slices using a new microsuperfusion device and on rat striatal synaptosomes. Under Mg2(
Publikováno v:
Psychopharmacology. 194(1)
Although locomotor response to d-amphetamine is considered as mediated by an increased release of dopamine in the ventral striatum, blockade of either alpha1b-adrenergic or 5-HT2A receptors almost completely inhibits d-amphetamine-induced locomotor r