Zobrazeno 1 - 10 of 33 pro vyhledávání: '"G. Giebing"'
1
Diguanosine pentaphosphate
Autor: Wolfgang Weiss, Walter Zidek, Joachim Jankowski, Markus Tölle, Vera Jankowski, Lars Henning, Uwe J. W. Tietge, Matthias P. Hörl, Markus van der Giet, G. Giebing
Publikováno v: Journal of Hypertension, 24(10), 1991-2000. LIPPINCOTT WILLIAMS & WILKINS
Objective Rho-kinase activity is increased in cardiovascular disease and in the pathophysiology of hypertension. Few endogenous factors are known that activate the Rho-kinase pathway. Stimulation of P2Y receptors activates the Rho-kinase pathway. Rec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96eee1d00dbbec38eb73c183b3f2af11
https://hdl.handle.net/11370/7b156dad-88fb-4c16-9148-51cb8aba19d0
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2
Identification and Characterization of Adenosine 5′-Tetraphosphate in Human Myocardial Tissue
Autor: Hartmut Schlüter, Timm H. Westhoff, Martin Tepel, Sven Schmidt, Jiankai Luo, Joachim Jankowski, Walter Zidek, Markus van der Giet, G. Giebing
Publikováno v: Journal of Biological Chemistry. 278:17735-17740
Endocrine functions of the human heart have been studied extensively. Only recently, nucleotidergic mechanisms have been studied in detail. Therefore, an isolation strategy was developed to isolate novel nucleotide compounds from human myocardium. Th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae4fb336a63ce5ce3f1f63d7a23b265
https://doi.org/10.1074/jbc.m300288200
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3
Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel
Autor: Ralf Köhler, Joachim Hoyer, Rudolf Schubert, Cor de Wit, Marcin Tysiac, G. Giebing, Volkmar Gross, Michael Bader, Ivica Grgic, Willm-Thomas Heyken, Larisa Vilianovich, Han Si, Tanja Maier, Stephanie E. Wölfle
Publikováno v: Circulation research. 99(5)
The endothelium plays a key role in the control of vascular tone and alteration in endothelial cell function contributes to several cardiovascular disease states. Endothelium-dependent dilation is mediated by NO, prostacyclin, and an endothelium-deri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9b02a81973acab46d3e9d525d636e6
https://pubmed.ncbi.nlm.nih.gov/16946141
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4
Arrestin-independent internalization and recycling of the urotensin receptor contribute to long-lasting urotensin II-mediated vasoconstriction
Autor: Markus Tölle, Markus van der Giet, Walter Rosenthal, Frank Neuschäfer-Rube, Walter Zidek, Jens Furkert, Alexander Oksche, Michael Beyermann, Jana Jürgensen, G. Giebing, Jenny Eichhorst
Publikováno v: Circulation research. 97(7)
Urotensin II (UII), which acts on the G protein-coupled urotensin (UT) receptor, elicits long-lasting vasoconstriction. The role of UT receptor internalization and intracellular trafficking in vasoconstriction has yet not been analyzed. Therefore, UI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1089271e2c23a1f94cd86cc184b873
https://pubmed.ncbi.nlm.nih.gov/16141412
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5
Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3
Autor: Vera Jankowski, Michael Schäfers, Petra Keul, Volker Brinkmann, Markus Tölle, Jerold Chun, Markus van der Giet, Joachim Jankowski, Walter Zidek, Karin von Wnuck Lipinski, Gilbert Schönfelder, G. Giebing, Bodo Levkau
Publikováno v: Circulation research. 96(8)
The novel immunomodulator FTY720 is effective in experimental models of transplantation and autoimmunity, and is currently undergoing Phase III clinical trials for prevention of kidney graft rejection. FTY720 is a structural analogue of sphingosine-1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b5fc1f3a62f8631052dff6c9e2c40a
https://pubmed.ncbi.nlm.nih.gov/15802614
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6
Increased plasma phenylacetic acid in patients with end-stage renal failure inhibits iNOS expression
Autor: J. Jankowski, M. van der Giet, V. Jankowski, S. Schmidt, M. Hemeier, B. Mahn, G. Giebing, M. Tölle, H. Luftmann, H. Schlüter, W. Zidek, M. Tepel
Publikováno v: The Journal of clinical investigation. 112(2)
NO prevents atherogenesis and inflammation in vessel walls by inhibition of cell proliferation and cytokine-induced endothelial expression of adhesion molecules and proinflammatory cytokines. Reduced NO production due to inhibition of either eNOS or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589dfbba879651212448024071a2f245
https://pubmed.ncbi.nlm.nih.gov/12865413
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10
The role of P2Y receptors in the control of blood pressure
Autor: M. Tölle, G. Giebing, Sven Schmidt, Van Der Giet M
Publikováno v: Drug News & Perspectives. 15:640
Extracellular nucleotides have been implicated in a number of physiological functions. Nucleotides act on cell-surface receptors known as P2 receptors, of which several subtypes have been cloned. P2X receptors are ligand-gated ion channels, whereas P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c1d26eb0fb776739cd72145f898320
https://doi.org/10.1358/dnp.2002.15.10.740237
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