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Autor:
E. V. Titova, D. S. Salionov, V. Yu. Poshekhontseva, S. M. Staroverov, V. S. Karasev, A. A. Shutov, Marina V. Donova, V. M. Nikolaeva, G. G. Vasiarov, V. V. Fokina
Publikováno v:
Applied Biochemistry and Microbiology. 56:699-707
Tacrolimus is known as the most effective immunosuppressive drug which is synthesized by actinobacteria of the genus Streptomyces. Its biosynthesis is accompanied by the formation of the structural analogs. A new method for the production of tacrolim