Zobrazeno 1 - 10
of 114
pro vyhledávání: '"G. G. Poirier"'
Autor:
Anna Ivana Scovassi, G G Poirier
Publikováno v:
Molecular and Cellular Biochemistry. 199:125-137
Poly(ADP-ribosylation) is a post-translational modification playing a relevant role in DNA damage recovery, DNA replication and viral integration. Several reports also suggest a modulation of this process during cell death by apoptosis. The aim of th
Publikováno v:
Journal of Biological Chemistry. 268:5480-5487
Rejoining of DNA single-strand breaks generated by treatment of plasmids with gamma-rays, neocarzinostatin, or bleomycin was catalyzed inefficiently by human cell extracts. The reaction was strongly promoted by the addition of NAD+, which was employe
Publikováno v:
Systems biology. 152(2)
Recently a state-space model with time delays for inferring gene regulatory networks was proposed. It was assumed that each regulation between two internal state variables had multiple time delays. This assumption caused underestimation of the model
Publikováno v:
Cellular and molecular life sciences : CMLS. 62(7-8)
Poly(ADP-ribose) glycohydrolase (PARG) is a catabolic enzyme that cleaves ADP-ribose polymers formed by members of the PARP family of enzymes. Despite its discovery and subsequent partial purification in the 1970s and the cloning of its single gene i
Publikováno v:
Molecular and cellular biochemistry. 224(1-2)
Poly(ADP-ribose) is a polymer (pADPr) that is synthesized by poly (ADP-ribose) polymerases in response to DNA damaging agents. For instance, chemical alkylating agents such as MNNG or physical stimulation of cells by gamma-rays are well known to indu
Publikováno v:
Methods in cell biology. 66
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 148
Publikováno v:
The Journal of biological chemistry. 275(20)
Poly(ADP-ribose) polymerase-1 (PARP-1) is an abundant nuclear enzyme that catalyzes the synthesis of poly(ADP-ribose) (pADPr) from its substrate NAD(+) upon binding to DNA strand breaks. Poly(ADP-ribosyl)ation has been implicated in many cellular pro
Autor:
A I, Scovassi, G G, Poirier
Publikováno v:
Molecular and cellular biochemistry. 199(1-2)
Poly(ADP-ribosylation) is a post-translational modification playing a relevant role in DNA damage recovery, DNA replication and viral integration. Several reports also suggest a modulation of this process during cell death by apoptosis. The aim of th
Publikováno v:
The Journal of biological chemistry. 274(40)
The abundant nuclear enzyme poly(ADP-ribose) polymerase (PARP) synthesizes poly(ADP-ribose) in response to DNA strand breaks. During almost all forms of apoptosis, PARP is cleaved by caspases, suggesting the crucial role of its inactivation. A few st