Výsledky vyhledávání

Vaccinia virus G1 protein: absence of autocatalytic self-processing

Autor: Tim Skern, F. G. G. Leite, Andreas Bergthaler

Publikováno v: Archives of Virology. 162:2803-2808

Vaccinia virus relies on a series of proteolytic cleavage events involving two viral proteins, I7 and G1, to complete its life cycle. Furthermore, G1 itself is cleaved during vaccinia virus infection. However, convincing evidence is lacking to show w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e24cde2f734501ac1631287950c5777
https://doi.org/10.1007/s00705-017-3409-y

Zobrazit plný text záznamu

RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6

Autor: Charlotte H. Durkin, Flávia G. G. Leite, Yoshiki Arakawa, Yutaka Handa, Ferran Valderrama, João V. Cordeiro, Michael Way

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
329.e7
Developmental Cell

Summary RhoA-mediated regulation of myosin-II activity in the actin cortex controls the ability of cells to contract and bleb during a variety of cellular processes, including cell migration and division. Cell contraction and blebbing also frequently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaf592e7861195ff6988eadbebb2913

Zobrazit plný text záznamu

SP600125 inhibits Orthopoxviruses replication in a JNK1/2 -independent manner: Implication as a potential antipoxviral

Autor: Paulo César Peregrino Ferreira, André Fabricio Pereira da Cruz, Alice A. Torres, Anna Carolina Corrêa Pereira, Flávia G. G. Leite, Jamaria A. P. Soares-Martins, Cláudio A. Bonjardim, Erna Geessien Kroon, Thaïs Souto-Padrón

Publikováno v: Antiviral Research

The pharmacological inhibitor SP600125 [anthra(1,9-cd)pyrazol-6(2H)-one 1,9-pyrazoloanthrone] has been largely employed as a c-JUN N-terminal kinase (JNK1/2) inhibitor. In this study, we evaluated whether pretreatment with SP600125 was able to preven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921f990ea43f0fc1318de46ea27ffd32
https://doi.org/10.1016/j.antiviral.2011.10.020

Zobrazit plný text záznamu

The dengue virus nonstructural protein 1 (NS1) increases NF-κB transcriptional activity in HepG2 cells

Autor: Erna Geessien Kroon, Flávia G. G. Leite, Breno de Mello Silva, Lirlândia P. Sousa, Alessandra Cristina Gomes-Ruiz, Flávio Guimarães da Fonseca, Paulo César Peregrino Ferreira, Cláudio A. Bonjardim, Paulo Filemon Paolucci Pimenta, Mauro M. Teixeira

Publikováno v: Archives of Virology. 156:1275-1279

Dengue virus nonstructural protein 1 (NS1) is a glycoprotein involved in viral RNA replication. NS1 associates with host cell proteins and can be found in lipid raft domains on the host cell surface, suggesting an involvement in signal transduction e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f498b7535269fb630f04d41ba7168cb5
https://doi.org/10.1007/s00705-011-0969-0

Zobrazit plný text záznamu

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

Autor: Flávia G. G. Leite, Alice A. Torres, Paulo César Peregrino Ferreira, Cláudio A. Bonjardim, Luciana G. Andrade, Jamária A. P. Soares, Thaïs Souto-Padrón, Lucíola S. Barcelos, Erna Geessien Kroon, Mauro M. Teixeira, Lirlândia P. Sousa

Publikováno v: Journal of Virology. 83:6883-6899

Viral manipulation of the transduction pathways associated with key cellular functions such as actin remodeling, microtubule stabilization, and survival may favor a productive viral infection. Here we show that consistent with the vaccinia virus (VAC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d648436506f67997b229a8d3f3060e84
https://doi.org/10.1128/jvi.00245-09

Zobrazit plný text záznamu

The role of signalling and the cytoskeleton during Vaccinia Virus egress

Autor: Michael Way, Flávia G. G. Leite

Publikováno v: Virus research. 209

Viruses are obligate intracellular parasites that are critically dependent on their hosts to replicate and generate new progeny. To achieve this goal, viruses have evolved numerous elegant strategies to subvert and utilise the different cellular mach

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478b1c600f8f9f9666b9017afc4ca054
https://pubmed.ncbi.nlm.nih.gov/25681743

Zobrazit plný text záznamu

A vaccinia virus-driven interplay between the MKK4/7-JNK1/2 pathway and cytoskeleton reorganization

Autor: Cláudio A. Bonjardim, Bruno S. A. F. Brasil, Alice A. Torres, Anna Carolina Corrêa Pereira, Thaïs Souto-Padrón, Paula Traktman, Jamaria A. P. Soares-Martins, Erna Geessien Kroon, Flávia G. G. Leite, Paulo César Peregrino Ferreira, Paulo F. P. Pimenta

Publikováno v: Journal of virology. 86(1)

Viral manipulation of transduction pathways associated with key cellular functions such as survival, response to microbial infection, and cytoskeleton reorganization can provide the supportive milieu for a productive infection. Here, we demonstrate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947bcef78e7f01ef944841c09f5f32f7
https://pubmed.ncbi.nlm.nih.gov/22031940

Zobrazit plný text záznamu

Effect of excess water in an oxisol on ammonium, nitrate, iron and manganese availability and nutrient uptake of two tropical forage species

Autor: W. Couto, G. G. Leite, C. Sanzonowics

Publikováno v: Plant and Soil. 73:159-166

A glasshouse experiment was conducted to determine how reduction conditions would affect plant nutrient availability and uptake in a red-yellow latosol (Acrustox). Soil analysis showed that the most important changes were a marked increase in extract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24443ee088d09b218f238e2e8b3ff470
https://doi.org/10.1007/bf02197712

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání