Zobrazeno 1 - 10
of 314
pro vyhledávání: '"G. Forstner"'
Publikováno v:
Attachment of Organisms to the Gut Mucosa ISBN: 9781351069977
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ca9364446adb8e5aa5e782e19eec60
https://doi.org/10.1201/9781351069977-3
https://doi.org/10.1201/9781351069977-3
Publikováno v:
Gut. 46:632-638
BACKGROUND AND AIMS—Gastric metaplasia is frequently seen in biopsies of the duodenal cap, particularly when inflamed or ulcerated. In its initial manifestation small patches of gastric foveolar cells appear near the tip of a villus. These cells co
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 277:G1041-G1047
Treatment of HT-29 cells with phorbol 12-myristate 13-acetate (PMA), an activator of protein kinase C (PKC), induces MUC2 expression. To investigate the role of PKC in regulating mucin genes in intestinal cells, we examined the regulation of MUC1, MU
Publikováno v:
Biochemical Journal. 341:593-600
Molecular chaperones are presumed to associate with large secretory mucin glycoproteins during their synthesis in the endoplasmic reticulum (ER), but have not been identified to date. We decided to look for possible involvement of the chaperones calr
Publikováno v:
Biochemical Journal. 331:323-330
The present study reveals that partial proteolytic degradation of rat Muc 2 mucin can occur rapidly even in the presence of a battery of proteinase inhibitors. During the initial steps of purification from homogenates of intestinal scrapings, degrada
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1326(1):7-11
A 3′ RACE technique was used to establish the nucleotide sequence encoding the C-terminal 379 amino acids of rat intestinal Muc3. Unlike the C-terminus of Muc2 and many secretory mucins, Muc3 contains two EGF motifs and a putative transmembrane dom
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 272:G31-G37
The phorbol ester, phorbol 12-myristate 13-acetate (PMA), induces mucin secretion in the colonic tumor cell line T84 in a Ca(2+)-independent manner. To determine whether a specific protein kinase C (PKC) isoform is involved in colonic cells, we compa
Autor:
Mary Oliver, Geraldine Kent, John R. Riordan, Janet F. Forstner, J. Kevin Foskett, Helena Frndova, Peter R. Durie, Gordon G. Forstner, Dean H. Percy, Manuel Buchwald
Publikováno v:
Scopus-Elsevier
Mouse models for cystic fibrosis (CF) with no CFTR function (Cftr-/-) have the disadvantage that most animals die of intestinal obstruction shortly after weaning. The objective of this research was to extend the lifespan of CF mice and characterize t
Publikováno v:
Biochemical Journal. 312:125-133
We have shown previously [McCool, Forstner and Forstner (1994) Biochem. J. 302, 111-118] using pulse-chase labelling of mucin with [3H]threonine that LS180 colonic tumour cells synthesize and secrete MUC2 without the addition of secretagogues. Treatm