Zobrazeno 1 - 10
of 273
pro vyhledávání: '"G. Foerster"'
Autor:
Derek K.L. Tsang, Ryan J. Wang, Oliver De Sa, Arshad Ayyaz, Elisabeth G. Foerster, Giuliano Bayer, Shawn Goyal, Daniel Trcka, Bibaswan Ghoshal, Jeffrey L. Wrana, Stephen E. Girardin, Dana J. Philpott
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The small intestinal epithelial barrier inputs signals from the gut microbiota in order to balance physiological inflammation and tolerance, and to promote homeostasis. Understanding the dynamic relationship between microbes and intestinal epithelial
Externí odkaz:
https://doaj.org/article/0018c12ca633427895fd121a96234369
Autor:
Elisabeth G. Foerster, Derek K.L. Tsang, Shawn Goyal, Susan J. Robertson, Lukian M. Robert, Heather Maughan, Catherine J. Streutker, Stephen E. Girardin, Dana J. Philpott
Publikováno v:
Mucosal Immunology. 16:135-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315f6e63d72436e9f078caf8a8a95d9e
https://doi.org/10.1016/j.mucimm.2023.02.001
https://doi.org/10.1016/j.mucimm.2023.02.001
Autor:
Johanna L A Paijmans, Axel Barlow, Kirstin Henneberger, Joerns Fickel, Michael Hofreiter, Daniel W G Foerster
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234385 (2020)
Utilising a reconstructed ancestral mitochondrial genome of a clade to design hybridisation capture baits can provide the opportunity for recovering mitochondrial sequences from all its descendent and even sister lineages. This approach is useful for
Externí odkaz:
https://doaj.org/article/c2c6306284b24d289ab147dc25174f1b
Autor:
Ivan Tattoli, Samuel A. Killackey, Elisabeth G. Foerster, Raphael Molinaro, Charles Maisonneuve, Muhammed A. Rahman, Shawn Winer, Daniel A. Winer, Catherine J. Streutker, Dana J. Philpott, Stephen E. Girardin
Publikováno v:
Cell Reports, Vol 14, Iss 11, Pp 2576-2586 (2016)
The mitochondrial Nod-like receptor protein NLRX1 protects against colorectal tumorigenesis through mechanisms that remain unclear. Using mice with an intestinal epithelial cells (IEC)-specific deletion of Nlrx1, we find that NLRX1 provides an IEC-in
Externí odkaz:
https://doaj.org/article/0516d2ca8656408cab832e57131bf2ae
Akademický článek
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Autor:
Stephen E. Girardin, Tapas Mukherjee, Dana J. Philpott, Juliana D.B. Rocha, Liliane Cabral-Fernandes, Elisabeth G. Foerster
Publikováno v:
Autophagy
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-mediated recycling of organelles and protein aggregates, as well as the destruction of intracellular pathogens. Its role in the maintenance of the intestinal epithelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a13b935ca31386175e6c0477d495e24
https://doi.org/10.1080/15548627.2021.1909406
https://doi.org/10.1080/15548627.2021.1909406
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 6:23-23
Background Associations have been found linking certain LRRK2 kinase domain gain-of-function variants, such as G2019S, to the development of Crohn’s disease and Parkinson’s disease, yet their exact roles in pathogenesis remains elusive. LRRK2 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::986256c2eae947b7d1b60413a082a6c7
https://doi.org/10.1093/jcag/gwac036.178
https://doi.org/10.1093/jcag/gwac036.178
Autor:
Elise Sofie Hovingh, Elisabeth G. Foerster, Tapas Mukherjee, Dana J. Philpott, Mena Abdel-Nour, Stephen E. Girardin
Publikováno v:
Archives of Biochemistry and Biophysics. 670:69-81
NOD1 and NOD2 are related intracellular sensors of bacterial peptidoglycan and belong to the Nod-like receptor (NLR) family of innate immune proteins that play fundamental and pleiotropic roles in host defense against infection and in the control of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b7aa3cb4dc8a5cd9e13d0ddcebe4b
https://doi.org/10.1016/j.abb.2018.12.022
https://doi.org/10.1016/j.abb.2018.12.022
Autor:
Elisabeth G Foerster, Catherine J Streutker, Heather Maughan, Derek KL Tsang, Lukian M Robert, Oliver De Sa, Stephen E Girardin, Dana J Philpott
Publikováno v:
The Journal of Immunology. 208:115.04-115.04
Crohn’s disease (CD) is characterized by a breakdown of the intestinal mucosal barrier. A genetic polymorphism of the autophagy gene ATG16L1 is associated with increased risk of developing CD, and it impairs the protective and regenerative function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3711275f5ec25b58c6065e4381178b7
https://doi.org/10.4049/jimmunol.208.supp.115.04
https://doi.org/10.4049/jimmunol.208.supp.115.04
Autor:
Daniel A. Winer, Derek S. Tsang, Catherine J. Streutker, Paul Lemire, Dave Prescott, Dana J. Philpott, Charles Maisonneuve, Elisabeth G. Foerster, Kaoru Geddes, Shawn Winer, Stephen E. Girardin, Ken Cadwell, Richard L. Ferrero, Ivan Tattoli, Alberto Martin, Tapas Mukherjee
Publikováno v:
SSRN Electronic Journal.
Summary Pioneering studies from the early 1980s suggested that bacterial peptidoglycan-derived muramyl peptides (MPs) could exert either stimulatory or immunosuppressive functions depending, in part, on chronicity of exposure. However, this Janus-fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::554a75a23ab222e8cf442d6af0015879
https://doi.org/10.2139/ssrn.3622484
https://doi.org/10.2139/ssrn.3622484