Zobrazeno 1 - 10
of 699
pro vyhledávání: '"G. FABER"'
Autor:
Benjamin G. Faber, Fiona Macrae, Mijin Jung, Benjamin E. Zucker, Rhona A. Beynon, Jonathan H. Tobias
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Recognising sex differences in disease prevalence can lead to clues as to its pathogenesis, for example the role of hormonal factors and related influences such as body composition, as well as forming the basis for new treatments. However, if differe
Externí odkaz:
https://doaj.org/article/bd66c5a2dd6f4b829f115632eb9e465d
Autor:
Rhona A. Beynon, Fiona R. Saunders, Raja Ebsim, Monika Frysz, Benjamin G. Faber, Jennifer S. Gregory, Claudia Lindner, Aliya Sarmanova, Richard M. Aspden, Nicholas C. Harvey, Timothy Cootes, Jonathan H. Tobias
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 2, Pp 100468- (2024)
Objective: We aimed to create an imaging biomarker for knee shape using knee dual-energy x-ray absorptiometry (DXA) scans and investigate its potential association with subsequent total knee replacement (TKR), independently of radiographic features o
Externí odkaz:
https://doaj.org/article/c4c3ff415ab44f73aa0ce2a06285f078
Autor:
Margot Geerts, Janneke G. J. Hoeijmakers, Brigitte A. B. Essers, Ingemar S. J. Merkies, Catharina G. Faber, Mariëlle E. J. B. Goossens
Publikováno v:
Health Expectations, Vol 27, Iss 2, Pp n/a-n/a (2024)
Abstract Introduction and Aim Small fibre neuropathy (SFN) is a peripheral neuropathy, leading to neuropathic pain and autonomic dysfunction. An evidence‐based standardized patient diagnostic SFN service has been implemented in the Netherlands for
Externí odkaz:
https://doaj.org/article/4bb03ba2be8c4718a7954bc43a5cc2fe
Autor:
Kaalindi Misra, Milena Ślęczkowska, Silvia Santoro, Monique M. Gerrits, Elisabetta Mascia, Margherita Marchi, Erika Salvi, Hubert J. M. Smeets, Janneke G. J. Hoeijmakers, Filippo Giovanni Martinelli Boneschi, Massimo Filippi, Giuseppe Lauria Pinter, Catharina G. Faber, Federica Esposito
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7248 (2024)
Small-Fiber Neuropathy (SFN) is a disorder of the peripheral nervous system, characterised by neuropathic pain; approximately 11% of cases are linked to variants in Voltage-Gated Sodium Channels (VGSCs). This study aims to broaden the genetic knowled
Externí odkaz:
https://doaj.org/article/6537d6a5e01446e4ab12c4ead59b6a9e
Autor:
Margot Geerts, Janneke G J Hoeijmakers, Brigitte A B Essers, Ingemar S J Merkies, Catharina G Faber, Mariëlle E J B Goossens
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0298881 (2024)
IntroductionSmall fiber neuropathy (SFN) is a common cause of neuropathic pain in peripheral neuropathies. Good accessibility of diagnostics and treatment is necessary for an accurate diagnosis and treatment of SFN. Evidence is lacking on the quality
Externí odkaz:
https://doaj.org/article/b189eb153cb4467ea518b0599235e76a
Autor:
Mirna Andelic, Margherita Marchi, Stefania Marcuzzo, Raffaella Lombardi, Catharina G. Faber, Giuseppe Lauria, Erika Salvi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101116- (2023)
Archived specimens, taken by standardized procedures in clinical practice, represent a valuable resource in translational medicine. Their use in retrospective molecular-based studies could provide disease and therapy predictors. Microfluidic array is
Externí odkaz:
https://doaj.org/article/61ea216ce05444ac8769e14814f332d8
Autor:
Benjamin G. Faber, Monika Frysz, Cindy G. Boer, Daniel S. Evans, Raja Ebsim, Kaitlyn A. Flynn, Mischa Lundberg, Lorraine Southam, April Hartley, Fiona R. Saunders, Claudia Lindner, Jennifer S. Gregory, Richard M. Aspden, Nancy E. Lane, Nicholas C. Harvey, David M. Evans, Eleftheria Zeggini, George Davey Smith, Timothy Cootes, Joyce Van Meurs, John P. Kemp, Jonathan H. Tobias
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104759- (2023)
Summary: Background: Hip minimum joint space width (mJSW) provides a proxy for cartilage thickness. This study aimed to conduct a genome-wide association study (GWAS) of mJSW to (i) identify new genetic determinants of mJSW and (ii) identify which mJ
Externí odkaz:
https://doaj.org/article/e65b32b807094d3195f523dc966a7bd4
Autor:
Aysun Damci, Janneke G. J. Hoeijmakers, Marlies den Hollander, Albère Köke, Marion de Mooij, Catharina G. Faber, Jeanine A. M. C. F. Verbunt
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundIn chronic pain syndromes, symptoms can fluctuate and change over time. Standard questionnaires cannot register these fluctuations. Nonetheless, the experience sampling method (ESM) is developed to collect momentary measurements of everyday
Externí odkaz:
https://doaj.org/article/81f265c469444484a2b3a9925d52ee85
Autor:
B. E. Zucker, R. Ebsim, C. Lindner, S. Hardcastle, T. Cootes, J. H. Tobias, M. R. Whitehouse, C. L. Gregson, B. G. Faber, A. E. Hartley
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background High bone mass (HBM, BMD Z-score ≥ + 3.2) and cam morphology (bulging of lateral femoral head) are associated with greater odds of prevalent radiographic hip osteoarthritis (rHOA). As cam morphology is itself a manifestation of
Externí odkaz:
https://doaj.org/article/5b3418039c4846b9a3d29b85f273fba6
Autor:
Catharina G. Faber, Nadine Attal, Giuseppe Lauria, Robert H. Dworkin, Roy Freeman, Katherine T. Dawson, Helen Finnigan, Amirhossein Hajihosseini, Himanshu Naik, Michael Serenko, Christopher J. Morris, Mona Kotecha
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101971- (2023)
Summary: Background: No pharmacological treatments are specifically indicated for painful small fibre neuropathy (SFN). CONVEY, a phase 2 enriched-enrolment study, evaluated the efficacy and safety of vixotrigine, a voltage- and use-dependent sodium
Externí odkaz:
https://doaj.org/article/98dd54c83e884b6a959fad1b27b55fcf