Zobrazeno 1 - 10
of 76
pro vyhledávání: '"G. F. Weinbauer"'
Publikováno v:
Primate Biology, Vol 7, Pp 1-4 (2020)
Enhanced pre- and postnatal development (ePPND) studies have become the default developmental toxicity test for biopharmaceuticals if nonhuman primates represent the relevant species. Spontaneous pregnancy losses and infant deaths can be significant
Externí odkaz:
https://doaj.org/article/36270d4747ae4e108a1bb54b245bbd2b
Autor:
R. Behr, G. F. Weinbauer
Publikováno v:
International Journal of Andrology. 24:126-135
CREM is a cAMP-related transcription factor and alternate promotor usage and splicing generate repressor and activator transcripts of CREM within the testis. CREM activators are highly expressed in post-meiotic haploid germ cells and are essential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb99cad62df866ce45d19a8746ce9ff3
https://doi.org/10.1046/j.1365-2605.2001.00277.x
https://doi.org/10.1046/j.1365-2605.2001.00277.x
Publikováno v:
Journal of Endocrinology. 168:25-38
We have investigated the antigonadotropic and antispermatogenic effects of exposure to a long-acting testosterone ester in the cynomolgus monkey model. Groups of five adult animals were exposed either to vehicle or to 10 mg/kg or 20 mg/kg testosteron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ee2ef93998a9e6159140d024679846
https://doi.org/10.1677/joe.0.1680025
https://doi.org/10.1677/joe.0.1680025
Publikováno v:
Journal of Endocrinology. 165:337-344
We investigated a possible modulation of growth hormone (GH) secretion by testosterone by measuring the growth hormone releasing hormone (GHRH)-stimulated and N-methyl-d,l-aspartic acid (NMA)-induced GH secretion in adult rhesus monkeys. Intact, orch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09dbeaa6cf3bee3a233b551f9a4398d
https://doi.org/10.1677/joe.0.1650337
https://doi.org/10.1677/joe.0.1650337
Autor:
J. Wessels, G. F. Weinbauer
Publikováno v:
Andrologia. 31:249-262
Spermatogenesis is a remarkably complex but precise process yielding highly differentiated haploid germ cells from diploid stem cells. Although many factors have been implicated in the paracrine control of spermatogenesis, functional proof is only av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f514204a7d3dba2cef74f176f1199d7
https://doi.org/10.1046/j.1439-0272.1999.00295.x
https://doi.org/10.1046/j.1439-0272.1999.00295.x
Publikováno v:
Clinical Endocrinology. 51:139-146
IntroductionUnder normal conditions male reproduction in mammalsrequires four distinct components which have to interact in aconcerted fashion with female reproductive functions toguarantee successful procreation:•sperm as the actual carrier of gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23f8e423c04aad39669b3b634d658d9d
https://doi.org/10.1046/j.1365-2265.1999.00846.x
https://doi.org/10.1046/j.1365-2265.1999.00846.x
Autor:
G. F. Weinbauer, Hanumanthappa Krishnamurthy, M. Arslan, G. Rosiepen, Eberhard Nieschlag, H. Aslam, G. Clemen
Publikováno v:
Journal of Endocrinology. 161:281-288
Although the gonadotropic control of the spermatogenic process is well established, the endocrine regulation of the timing and kinetics of germ cell development has received little attention. We found previously that the administration of a GnRH anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fdeaecf4ea99a52930d955de870483c
https://doi.org/10.1677/joe.0.1610281
https://doi.org/10.1677/joe.0.1610281
Publikováno v:
Journal of Endocrinology. 159:103-110
The effects of bovine inhibin, testosterone and GnRH on gonadotrophin secretion by primate pituitary cells were characterized in vitro using pituitaries from six male rhesus monkeys and one male cynomolgus monkey. The effect of inhibin on basal secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3d3bf06f2664573889d4f20cdecdbc
https://doi.org/10.1677/joe.0.1590103
https://doi.org/10.1677/joe.0.1590103
Publikováno v:
Journal of Endocrinology. 156:23-34
Meiosis constitutes a crucial phase of spermatogenesis since the recombination of genetic information and production of haploid round spermatids need to be achieved. Although it is well established that gonadotrophic hormones are required for complet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31595fab431334f946641d9e596301fb
https://doi.org/10.1677/joe.0.1560023
https://doi.org/10.1677/joe.0.1560023
Publikováno v:
Molecular Human Reproduction. 4:9-15
Mice lacking the functional cAMP responsive element modulator (CREM) gene, a component of cAMP-mediated signal transduction, exhibit a specific arrest of round spermatid development although follicle stimulating hormone (FSH) and androgen secretion a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d5848c27786bcbc1e512a08c31026a
https://doi.org/10.1093/molehr/4.1.9
https://doi.org/10.1093/molehr/4.1.9