Zobrazeno 1 - 10
of 12
pro vyhledávání: '"G. F. Lundell"'
Autor:
Erb Jm, Douglas J. Pettibone, D. S. Perlow, S.-H. L. Chiu, Peter D. Williams, Roger M. Freidinger, Mark G. Bock, L. A. Carroll, Steven M. Pitzenberger, Michael J. Kaufman, J. C. Culberson, B. E. Evans, J. S. Murphy, G. F. Lundell, S. L. Fitzpatrick, Bradley V. Clineschmidt, Joseph M. Pawluczyk, Richard G. Ball, P. S. Anderson
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e918b89df24f6d0f8346ecd5acf39bb
https://doi.org/10.1002/chin.199427220
https://doi.org/10.1002/chin.199427220
Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)
Autor:
Kenneth E. Rittle, Mary Beth Young, Roger M. Freidinger, G. F. Lundell, Stanley L. Gaul, Philippe G. Nantermet, James C. Barrow, Robert J. Gould, Cindra L. Condra, Kris Prendergast, Janetta M. Pellicore, Harold G. Selnick, Rodney A. Bednar, Jerzy Karczewski, Thomas M. Connolly
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(3)
The synthesis and biological evaluation of a series of nonpeptidic small molecule antagonists of the human platelet thrombin receptor (PAR-1) are described. Optimization of the 5-amino-3-arylisoxazole lead resulted in an approximate 100-fold increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8687c72a020cc3ad8b193b2a85f9f2a8
https://pubmed.ncbi.nlm.nih.gov/11814787
https://pubmed.ncbi.nlm.nih.gov/11814787
Autor:
B E, Evans, G F, Lundell, K F, Gilbert, M G, Bock, K E, Rittle, L A, Carroll, P D, Williams, J M, Pawluczyk, J L, Leighton, M B, Young
Publikováno v:
Journal of medicinal chemistry. 36(25)
Non-peptide antagonists of the peptide hormone oxytocin (OT) with nanomolar OT receptor affinities are described. These compounds incorporate novel amido- and amidoalkylcamphor variations to the lead structure L-366,509 (1) to achieve receptor affini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3adb35f406f6b71bca5c35af1603733
https://pubmed.ncbi.nlm.nih.gov/8258821
https://pubmed.ncbi.nlm.nih.gov/8258821
Autor:
J H, Jones, P S, Anderson, J J, Baldwin, B V, Clineschmidt, D E, McClure, G F, Lundell, W C, Randall, G E, Martin, M, Williams, J M, Hirshfield
Publikováno v:
Journal of Medicinal Chemistry. 27:1607-1613
A series of tricyclic oxazines, namely, the 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, have been synthesized and assayed for dopamine agonist activity. One of the members of this series, compound (+)VII-15, was found to be a remarkably potent agoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1781275e4c4b17600ea227fc6bcb2c
https://doi.org/10.1021/jm00378a014
https://doi.org/10.1021/jm00378a014
Publikováno v:
Tetrahedron Letters. 12:2787-2790
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d92a25738773b7ef31325a473c698e
https://doi.org/10.1016/s0040-4039(01)96980-1
https://doi.org/10.1016/s0040-4039(01)96980-1
Autor:
D. E. Mcclure, P. K. Lumma, J. Hirshfield, W. C. Randall, Gregory E. Martin, G. Smith, James H. Jones, John J. Baldwin, B. V. Clineschmidt, P. S. Anderson, G. F. Lundell, Michael Williams
Publikováno v:
Chemischer Informationsdienst. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59722bd407d0cf4a359fa2ab6d36bc99
https://doi.org/10.1002/chin.198523229
https://doi.org/10.1002/chin.198523229
Autor:
Ralph Hirschmann, R. Hall, Charles S. Sweet, Gerald S. Ponticello, N. N. Share, A. Scriabine, John J. Baldwin, G. F. Lundell, Edward L. Engelhardt, Ludden Ct
Publikováno v:
Chemischer Informationsdienst. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bccd923d3a5f7a721e6adeaa63909ca
https://doi.org/10.1002/chin.197941194
https://doi.org/10.1002/chin.197941194
Publikováno v:
Chemischer Informationsdienst. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8df345636799a789b7c62c6f726fd05
https://doi.org/10.1002/chin.197743191
https://doi.org/10.1002/chin.197743191
Publikováno v:
Chemischer Informationsdienst. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2397a2458fd8a52bdc95aaf9750d089d
https://doi.org/10.1002/chin.197543269
https://doi.org/10.1002/chin.197543269
Autor:
N. P. Gould, P. J. King, D. F. Veber, Roger M. Freidinger, Tsing-Bau Chen, Carl F. Homnick, Mark G. Bock, Robert M. DiPardo, J. P. Springer, D. J. Cerino, Victor J. Lotti, B. E. Evans, P. S. Anderson, Kenneth E. Rittle, G. F. Lundell, K. A. Kunkel, W. L. Whitter, R. S. L. Chang, J. Hirshfield
Publikováno v:
ChemInform. 18
Coupling of the benzophenones (I) with D-tryptophan methyl ester hydrochloride (II) gives the benzodiazepinones (III).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::747c3dc8bb2bee2f1d09c71ff31e91f5
https://doi.org/10.1002/chin.198750243
https://doi.org/10.1002/chin.198750243