Zobrazeno 1 - 10
of 87
pro vyhledávání: '"G. Ekin Atilla"'
Autor:
Ricardo X. Ramirez, Oluwatoyin Campbell, Apoorva J. Pradhan, G. Ekin Atilla-Gokcumen, Viviana Monje-Galvan
Publikováno v:
Frontiers in Chemistry, Vol 10 (2023)
Lipids, the structural part of membranes, play important roles in biological functions. However, our understanding of their implication in key cellular processes such as cell division and protein-lipid interaction is just emerging. This is the case f
Externí odkaz:
https://doaj.org/article/599db79a3b4d47e784f86d08d10c381d
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11178 (2022)
One of the classic hallmarks of cancer is the imbalance between elevated cell proliferation and reduced cell death. Ceramide, a bioactive sphingolipid that can regulate this balance, has long been implicated in cancer. While the effects of ceramide o
Externí odkaz:
https://doaj.org/article/ee607902444a466cb29ad0c4bbca4e0b
Autor:
Purab Pal, Alec Millner, Svetlana E. Semina, Rosemary J. Huggins, Logan Running, Diana S. Aga, Debra A. Tonetti, Rachel Schiff, Geoffrey L. Greene, G. Ekin Atilla-Gokcumen, Jonna Frasor
Publikováno v:
Cancers, Vol 14, Iss 10, p 2380 (2022)
ET resistance is a critical problem for estrogen receptor-positive (ER+) breast cancer. In this study, we have investigated how alterations in sphingolipids promote cell survival in ET-resistant breast cancer. We have performed LC-MS-based targeted s
Externí odkaz:
https://doaj.org/article/b6e64b9a5a7a4df58c5bdc1c3f525da0
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: Siderophores are small molecule metal chelators secreted in sparse quantities by their native microbial hosts but can be engineered for enhanced production from heterologous hosts like Escherichia coli. These molecules have been proved to be
Externí odkaz:
https://doaj.org/article/72cf0848a8d943b2b740198730954ea0
Autor:
Alec Millner, G. Ekin Atilla-Gokcumen
Publikováno v:
Metabolites, Vol 10, Iss 9, p 339 (2020)
Lipids are emerging as key players of senescence. Here, we review the exciting new findings on the diverse roles of lipids in cellular senescence, most of which are enabled by the advancements in omics approaches. Senescence is a cellular process in
Externí odkaz:
https://doaj.org/article/90797fcdd8c047a4bd300e5f5daa2a5a
Publikováno v:
Molecular Omics. 19:205-217
Necroptosis is a type of programmed cell death associated with an inflammatory phenotype. Pradhan et al. reviews recent -omics-based studies that help better understand necroptotic signaling and inflammatory response associated with it.
Publikováno v:
RSC Chemical Biology. 4:310-322
Necroptosis is accompanied by accumulation of lipids. This study shows that SREBPs are activated and cause increase in the production of very long-chain fatty acids during necroptosis.
Autor:
Jonathan F. Lovell, G. Ekin Atilla-Gokcumen, Shuai Shao, Kevin A. Carter, Nasi Li, Jumin Geng, Dandan Luo
Localization of cationic liposomes in tumor microvessels. Intact vessels were stained with intravenous Hoechst's dye administration prior to sacrifice. A scale bar of 100 µm is shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c563a7451dd7bfbbc88390d71776bb4
https://doi.org/10.1158/1535-7163.22508560.v1
https://doi.org/10.1158/1535-7163.22508560.v1
Autor:
Jonathan F. Lovell, G. Ekin Atilla-Gokcumen, Shuai Shao, Kevin A. Carter, Nasi Li, Jumin Geng, Dandan Luo
Dox Pharmacokinetics of neutral Dox-PoP liposomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e88f6b96eac6364aca42eb89024cafd
https://doi.org/10.1158/1535-7163.22508551
https://doi.org/10.1158/1535-7163.22508551
Autor:
Jonathan F. Lovell, G. Ekin Atilla-Gokcumen, Shuai Shao, Kevin A. Carter, Nasi Li, Jumin Geng, Dandan Luo
Complete Supporting Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8797fb33cc43466548c2933843341d
https://doi.org/10.1158/1535-7163.22508575.v1
https://doi.org/10.1158/1535-7163.22508575.v1