Zobrazeno 1 - 10
of 116
pro vyhledávání: '"G. E. WILSON"'
Autor:
M. V. Roloff, A. G. E. Wilson
1. Animal selection and extrapolation - the problem defined Part I: Current industrial practices and regulatory status of animal selection and extrapolation 2. Current EPA perspectives on animal selection and extrapolation 3. Current FDA perspectives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583d62cee5c5bc7a0f8ba71e75b05e77
https://doi.org/10.1201/9781003069416
https://doi.org/10.1201/9781003069416
Autor:
Suma Gopinathan, Kenneth G. Carson, Alan G. E. Wilson, Zhi-Ming Ding, Bryce Alden Harrison, Damaris S. Diaz, Angela L. Harris, Debra Bruce, Nicole Cathleen Goodwin, Emily O’Neill, David R. Powell, Melinda Smith, Eric Strobel, David B. Rawlins, Wendy Xiong, Ling Li, Andrea Y. Thompson, Mary Thiel, Faika Mseeh
Publikováno v:
Journal of Medicinal Chemistry. 60:710-721
The increasing number of people afflicted with diabetes throughout the world is a major health issue. Inhibitors of the sodium-dependent glucose cotransporters (SGLT) have appeared as viable therapeutics to control blood glucose levels in diabetic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8541b1a58e42776d5a5b4773e40351f7
https://doi.org/10.1021/acs.jmedchem.6b01541
https://doi.org/10.1021/acs.jmedchem.6b01541
Autor:
Alan G E Wilson
Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and
Autor:
Donna R. Farmer, Charles E. Healy, Alan G. E. Wilson, William F. Heydens, Mark A. Martens, Kathy J. Hotz, Larry D. Kier
Publikováno v:
Journal of Agricultural and Food Chemistry. 56:1517-1523
A broad array of in vitro and in vivo assays has consistently demonstrated that glyphosate and glyphosate-containing herbicide formulations (GCHF) are not genotoxic. Occasionally, however, related and contradictory data are reported, including findin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beacb65d9a938e138fef6d8fa4c110ba
https://doi.org/10.1021/jf072581i
https://doi.org/10.1021/jf072581i
Autor:
Philip S. Burton, Massimiliano Germani, Patrizia Crivori, Italo Poggesi, Mark E. Smith, Maurizio Rocchetti, Alan G. E. Wilson
Publikováno v:
European Journal of Pharmaceutical Sciences. 31:190-201
The objective of this study was to evaluate a physiologically based pharmacokinetic (PBPK) approach for predicting the plasma concentration-time curves expected after intravenous administration of candidate drugs to rodents. The predictions were base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39bd011189218b1c9807335bfdf958b0
https://doi.org/10.1016/j.ejps.2007.03.008
https://doi.org/10.1016/j.ejps.2007.03.008
Autor:
Alan G E Wilson
Publikováno v:
New Horizons in Predictive Drug Metabolism and Pharmacokinetics
Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8815bb8bb1fbd10ab7a8858f7a56963e
https://doi.org/10.1039/9781782622376
https://doi.org/10.1039/9781782622376
Autor:
G E Wilson
Publikováno v:
Histopathology. 40:380-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5c4ff478519dd13f66ada4292d81350
https://doi.org/10.1046/j.1365-2559.2002.t01-1-01365.x
https://doi.org/10.1046/j.1365-2559.2002.t01-1-01365.x
Publikováno v:
Toxicological Sciences. 55:36-43
Chronic administration of alachlor has been shown to produce neoplastic responses in the nasal turbinate mucosa, glandular stomach mucosa, and thyroid follicular epithelium of rats. Subsequent studies have shown that specific metabolic activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffd5b6857005e61b599e8c73c62525c
https://doi.org/10.1093/toxsci/55.1.36
https://doi.org/10.1093/toxsci/55.1.36
Autor:
Alan G. E. Wilson, Ayako S. Takei
Publikováno v:
Journal of Pesticide Science. 25:75-83
ブタクロールは, 米国モンサント・カンパニーが開発した一年生イネ科雑草および一部の広葉雑草を対象とする稲作用除草剤である. 動物実験の結果, 本剤の哺乳動物に対する急性経口,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417310a8bac6810c67b3aae3726a9e45
https://doi.org/10.1584/jpestics.25.75
https://doi.org/10.1584/jpestics.25.75
Publikováno v:
Sexually Transmitted Infections. 75:172-177
OBJECTIVES: To determine the prevalence of high grade anal intraepithelial neoplasia (HGAIN), the value of anal cytology in screening for HGAIN, and the characterisation of epidemiological factors and human papillomavirus (HPV) types. METHODS: Prospe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2354966be72b74d92f79b665dbf9dda9
https://doi.org/10.1136/sti.75.3.172
https://doi.org/10.1136/sti.75.3.172