Zobrazeno 1 - 10
of 12
pro vyhledávání: '"G. E. Hatch"'
Autor:
Elina Toskala, Gregory W. Mango, G. E. Hatch, Susan D. Reynolds, Barry R. Stripp, Charles G. Plopper, Brian K. Tarkington, Viviana J. Wong
Publikováno v:
Toxicology and Applied Pharmacology. 213:74-85
Increases in Clara cell abundance or cellular expression of Clara cell secretory protein (CCSP) may cause increased tolerance of the lung to acute oxidant injury by repeated exposure to ozone (O{sub 3}). This study defines how disruption of the gene
Autor:
A. R. Whorton, Andrew J. Ghio, Alvin L. Crumbliss, G. E. Hatch, John R. Hoidal, Thomas P. Kennedy
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 263:L511-L518
Inhalation of silicates induces a variety of lung diseases in humans. The molecular mechanism(s) by which these dusts cause disease is not known. Because several naturally occurring mineral oxides have large amounts of transition metal ions on their
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 80(6)
Previous studies from this laboratory have demonstrated a concentration-related hypothermia and increases in bronchoalveolar lavage (BAL) fluid indexes of toxicity in the rat after exposure to environmentally relevant levels of ozone (O3). In similar
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 71(2)
Phosgene inhalation causes a severe noncardiogenic pulmonary edema characterized by an influx of neutrophils into the lung. To study the role of neutrophils in lung injury and mortality after phosgene, we investigated the effects of leukocyte depleti
Publikováno v:
Toxicological Sciences. 7:49-57
Publikováno v:
Environmental research. 37(1)
The effects of inhalation exposure of mice or rats to 9.4 mg/m3 volcanic ash, 2.5 mg/m3 SO2, or both on host defense mechanisms were assessed. Cytologic changes in pulmonary lavage fluid included an increase in percentage polymorphonuclear leukocytes
Autor:
M, Aissa, G E, Hatch
Publikováno v:
Basic life sciences. 49
Publikováno v:
Environmental research. 37(1)
Rats were exposed by inhalation to 9.4 mg/m3 size-fractionated volcanic ash for 5 days (2 hr/day) and examined for changes in pulmonary function and histology for periods of up to 1 year. Fine-mode volcanic ash, SO2, and a combination of ash and SO2
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 119(2)
Publikováno v:
The American review of respiratory disease. 131(5)
Basal lung concentrations of ascorbic acid (AA), nonprotein sulfhydryls (NPSH), and alpha-tocopherol (alpha-T) were determined in rabbits, guinea pigs, rats, hamsters, mice, domestic pigs and sheep, and in human lung samples obtained from cancer surg