Zobrazeno 1 - 10
of 146
pro vyhledávání: '"G. E. Dobretsov"'
Autor:
M. G. Uzbekov, N. V. Smolina, T. I. Syrejshchikova, V. V. Brilliantova, G. E. Dobretsov, S. N. Shikhov
Publikováno v:
Neurochemical Journal. 16:480-484
Autor:
E. D. Syromyatnikova, V. V. Brilliantova, M. G. Uzbekov, N. V. Smolina, T. I. Syrejshchikova, G. E. Dobretsov
Publikováno v:
Neurochemical Journal. 15:254-259
—The kinetics of fluorescence decay of the K-35 probe and the tryptophan amino acid residue were measured after the addition of sodium hypochlorite in human albumin serum (HSA). The K-35 fluorescent probe (excitation 405 nm, fluorescence 530 nm) bi
Autor:
N. V. Smolina, V. V. Brilliantova, G. E. Dobretsov, T. I. Syrejshchikova, E. D. Syromyatnikova, M. G. Uzbekov
Publikováno v:
Biophysics. 64:95-99
—The goal of this work was to search for blood serum parameters that would be associated with the state of patients with mental disorders. Such indicators are needed for an objective assessment of this state versus the prevailing subjective evaluat
Publikováno v:
Neurochemical Journal. 12:107-110
In this paper, the state of the body’s antioxidant defense was studied using the state of thiol groups in the albumin in patients with their first episode of schizophrenia (FES). We examined 21 patients with the first psychotic attack of schizophre
Publikováno v:
Biophysics. 62:286-290
It is known that the conformation of human serum albumin binding sites is sensitive to pathological processes. In this work, changes in the physical–chemical properties of albumin binding sites in melancholic depression were studied. The K-35 fluor
Publikováno v:
Biochemical and Biophysical Research Communications. 478:462-466
Human serum albumin (HSA) transports many ligands including small aromatic molecules: metabolites, drugs etc. Phenylbutazone is an anti-inflammatory drug, which binds to the drug-binding site I of HSA. Its interaction with this site has been studied
Publikováno v:
Current drug discovery technologies. 15(3)
BACKGROUND Risperidone is an antipsychotic drug. In blood, this drug binds mainly to human serum albumin (HSA) and is also transported by HSA. METHOD To study certain details of the interaction between risperidone and HSA, a fluorescent dye CAPIDAN w
Publikováno v:
Biophysics. 59:183-188
Mechanisms of fluorescence quenching of aromatic chromophores by water are reviewed. The mechanisms include polarity of chromophore environment, proton or electron transfer between the excited chromophore and water. A hypothesis is proposed that the
Autor:
G. E. Dobretsov
Publikováno v:
Biophysics. 58:577-582
A brief history of the development of the method of fluorescent probes and examples of its application are presented. Works done at the 2nd Moscow medical institute and institute of physical chemical medicine in collaboration with other institutes on
Autor:
Tamara P. Klimova, T. A. Babushkina, Oleg M. Sarkisov, Boris M. Polyak, Victor Sverbil, Tatyana Syrejshchikova, Yury Gryzunov, Natalya Smolina, G. E. Dobretsov, Alexandr Peregudov
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 251:134-140
Fluorescent probe CAPIDAN (or “K-35”), N-(p-carboxyphenyl)imide of 4-(dimethylamino)naphthalic acid, is used as a detector of structural changes in human serum albumin in some diseases. In these cases observed changes in its fluorescence can be u