Zobrazeno 1 - 10
of 86
pro vyhledávání: '"G. E. Bigelow"'
Publikováno v:
Psychopharmacology. 123:15-25
The present study was conducted to determine whether methadone maintenance alters the pharmacodynamic effects of single doses of cocaine. Twenty-two current users of IV cocaine who were not seeking treatment for their illicit cocaine use participated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ad403242c394391c90de9f1c305371
https://doi.org/10.1007/bf02246276
https://doi.org/10.1007/bf02246276
Publikováno v:
American Journal of Public Health. 84:207-210
OBJECTIVES. Intravenous drug users are at high risk for medical illness, yet many are medically underserved. Most methadone treatment programs have insufficient resources to provide medical care. The purpose of this study was to test the efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3998de084af9f80691490aa7582b89f
https://doi.org/10.2105/ajph.84.2.207
https://doi.org/10.2105/ajph.84.2.207
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
Preclinical studies have demonstrated that kappa-opioid agonists can attenuate the neurochemical and behavioral effects of cocaine that are related to its reinforcing efficacy, suggesting that kappa-agonists may serve as pharmacotherapies for cocaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba3f6fcba527c1450fb1ac689b6af84f
https://pubmed.ncbi.nlm.nih.gov/11561074
https://pubmed.ncbi.nlm.nih.gov/11561074
Publikováno v:
Experimental and clinical psychopharmacology. 9(3)
The study tested a voucher-based abstinence reinforcement procedure for reducing opiate and cocaine use in a population of treatment-resistant opiate- and cocaine-abusing methadone patients. Vouchers exchangeable for goods and services were contingen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49a772767d409205976cfb353e938903
https://pubmed.ncbi.nlm.nih.gov/11534542
https://pubmed.ncbi.nlm.nih.gov/11534542
Autor:
K L, Preston, G E, Bigelow
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(1)
The purpose of this study was to examine the discrimination of agonist-antagonist opioids in humans trained in a two-choice hydromorphone/not hydromorphone discrimination. Eight adult male volunteers with histories of opioid abuse who were not curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::137f62b5c6ac575a660c5926a0874196
https://pubmed.ncbi.nlm.nih.gov/10991968
https://pubmed.ncbi.nlm.nih.gov/10991968
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(3)
The discriminative stimulus and subjective effects of opioid mixed agonist-antagonists were assessed in volunteer nondependent heroin users trained in a three-choice drug discrimination procedure to discriminate among the effects of i.m. administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6aa89804541c038f7320b3846fc9d553
https://pubmed.ncbi.nlm.nih.gov/10336526
https://pubmed.ncbi.nlm.nih.gov/10336526
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(2)
levo-alpha-Acetylmethadol (LAAM) and methadone are full mu-opioid agonists used to treat opioid dependence. Current labeling indicates that LAAM is less potent than methadone. Clinical studies have not determined the relative potency of these drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe3a8bd0cc5504ed9de70dd17e3a1580
https://pubmed.ncbi.nlm.nih.gov/10215673
https://pubmed.ncbi.nlm.nih.gov/10215673
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(1)
Levo-alpha-acetylmethadol (LAAM) is a long-acting opioid agonist approved for use as a maintenance treatment for opioid dependence. Previous clinical studies report that the onset of the effects of LAAM is slower after parenteral administration than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d4eb1a72af6c3960913b378c788e8a1
https://pubmed.ncbi.nlm.nih.gov/9535996
https://pubmed.ncbi.nlm.nih.gov/9535996
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(2)
Levo-alpha-acetylmethadol (LAAM) currently is approved as an opioid maintenance treatment. This double-blind study was designed to characterize withdrawal suppression and opioid blockade produced by two different LAAM maintenance doses. Outpatient op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4c53871e8e4243e4d4567c489060345
https://pubmed.ncbi.nlm.nih.gov/9580575
https://pubmed.ncbi.nlm.nih.gov/9580575
Autor:
T, Eissenberg, G E, Bigelow, E C, Strain, S L, Walsh, R K, Brooner, M L, Stitzer, R E, Johnson
Publikováno v:
JAMA. 277(24)
To compare the clinical efficacy of different doses of levomethadyl acetate hydrochloride (known as LAAM) in the treatment of opioid dependence.A randomized controlled, double-blind, parallel group, 17-week study.Outpatient facilities at Johns Hopkin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94f32e9b31f7e4c4c6878aef6a19d1c5
https://pubmed.ncbi.nlm.nih.gov/9200635
https://pubmed.ncbi.nlm.nih.gov/9200635