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Publikováno v:
Rep Pract Oncol Radiother
Introduction Pulmonary large-cell neuroendocrine carcinoma (LCNEC) is a very rare disease, comprising approximately 3% of lung cancers. Even for Stage I disease, recurrence after resection is common, with a poor five-year overall survival. We present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0576041c4f4f31500b1bc6c08e02b6
https://doi.org/10.1016/j.rpor.2019.08.005
https://doi.org/10.1016/j.rpor.2019.08.005
Publikováno v:
Regular and young investigator award abstracts.
Background Checkpoint inhibitors are a promising therapy for patients with solid tumors; however, many patients require additional therapies to maximize clinical benefit or overcome resistance.1 The type-1 cytokine interleukin-21 (IL-21) is a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb32f867219d0898e33a299805b422d8
https://doi.org/10.1136/jitc-2020-sitc2020.0417
https://doi.org/10.1136/jitc-2020-sitc2020.0417
Autor:
H. Henary, John C. Krauss, Timothy J. Price, Geoffrey I. Shapiro, Marwan Fakih, Timothy F. Burns, Jayesh Desai, Crystal S. Denlinger, John H. Strickler, Keunchil Park, Brett E. Houk, Funda Meric-Bernstam, Ramaswamy Govindan, J. Russell Lipford, Fabrice Barlesi, Andrew L. Coveler, James Kuo, Gregory Friberg, Adrian G. Sacher, Tae Won Kim, Pamela N. Munster, Gataree Ngarmchamnanrith, J. Kim, Jude Canon, David S. Hong, Gerald S. Falchook, Piro Lito, Yung-Jue Bang, Bob T. Li, Yasutoshi Kuboki, J. Ngang, G. Durm, Grace K. Dy, Suresh S. Ramalingam
Publikováno v:
N Engl J Med
BACKGROUND: No therapies for targeting KRAS mutations in cancer have been approved. The KRAS p.G12C mutation occurs in 13% of non–small-cell lung cancers (NSCLCs) and in 1 to 3% of colorectal cancers and other cancers. Sotorasib is a small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc9a0fa8207a8435df002a3a37d9a96
https://pubmed.ncbi.nlm.nih.gov/33497555
https://pubmed.ncbi.nlm.nih.gov/33497555
Autor:
Thomas J. Birdas, G. Durm, Kenneth A. Kesler, H. Liu, DuyKhanh P. Ceppa, Shadia I. Jalal, Nasser H. Hanna, Karen M. Rieger
Publikováno v:
Journal of Thoracic Oncology. 16:S257-S258
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c71c9ac6afd87ae9424f4b11cf8aec80
https://doi.org/10.1016/j.jtho.2021.01.374
https://doi.org/10.1016/j.jtho.2021.01.374
Autor:
Kenneth A. Kesler, G. Durm, Shadia I. Jalal, Thomas J. Birdas, DuyKhanh P. Ceppa, Lawrence H. Einhorn, Nasser H. Hanna, Melissa Yan, Karen M. Rieger
Publikováno v:
Journal of Thoracic Oncology. 16:S187-S188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34f1d4c4b257c230bcd49ddf2ab0ab00
https://doi.org/10.1016/j.jtho.2021.01.071
https://doi.org/10.1016/j.jtho.2021.01.071
Autor:
Gataree Ngarmchamnanrith, David S. Hong, Grace K. Dy, Timothy F. Burns, Ramaswamy Govindan, G. Durm, K. Park, J. Kim, Fabrice Barlesi, Agnes Ang, Bob T. Li, John H. Strickler, Abraham Anderson, J.R. Lipford, Y-J. Bang, Gerald Steven Falchook
Publikováno v:
Journal of Thoracic Oncology. 16:S28-S29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47b1e94348cb30982f8768d863e8061
https://doi.org/10.1016/j.jtho.2020.10.136
https://doi.org/10.1016/j.jtho.2020.10.136
Autor:
Abraham Anderson, Gerald Steven Falchook, Ramaswamy Govindan, Timothy F. Burns, Agnes Ang, Bob T. Li, J. Kim, Grace K. Dy, Y-J. Bang, K.C. Park, Gataree Ngarmchamnanrith, David S. Hong, Fabrice Barlesi, John H. Strickler, R. Lipford, G. Durm
Publikováno v:
Revue des Maladies Respiratoires Actualités. 13:121-122
Introduction L’etude de phase 1 du sotorasib, inhibiteur de KRASG12C, a demontre un profil de tolerance favorable et une activite antitumorale chez les pts atteints de CPNPC, KRASG12C mute, avec un taux de reponse objective (TRO) de 54 % sur 13 pts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cedc10a6a21260a3d7727654ac74117f
https://doi.org/10.1016/j.rmra.2020.11.250
https://doi.org/10.1016/j.rmra.2020.11.250
Autor:
J.H. Strickler, M. Fakih, T.J. Price, J. Desai, G. Durm, J.C. Krauss, Y. Kuboki, T.W. Kim, A. Sacher, H. Henary, J. Kim, D.S. Hong
Publikováno v:
Annals of Oncology. 31:S1274-S1275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30e7b12f7abd019f4585fdde844c947e
https://doi.org/10.1016/j.annonc.2020.10.103
https://doi.org/10.1016/j.annonc.2020.10.103
Autor:
D.S. Hong, Y-J. Bang, F. Barlesi, G. Durm, G.S. Falchook, R. Govindan, G.K. Dy, K. Park, J.H. Strickler, T.F. Burns, J. Kim, A. Ang, J.R. Lipford, G. Ngarmchamnanrith, A. Anderson, B.T. Li
Publikováno v:
Annals of Oncology. 31:S1389-S1390
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f6fab7404ea912cb5388b97c473a0b6
https://doi.org/10.1016/j.annonc.2020.10.375
https://doi.org/10.1016/j.annonc.2020.10.375