Zobrazeno 1 - 10
of 441
pro vyhledávání: '"G. Dent"'
Publikováno v:
eLife, Vol 13 (2024)
The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in pancreatic ductal adenocardinoma (PDAC) tumours. In this study, we characterised previously unexplored endogenous RELA-GFP dynam
Externí odkaz:
https://doaj.org/article/026c08f779a245469dc5d95cd359a962
Publikováno v:
Journal of Vertebrate Paleontology, 1997 Sep 01. 17(3), 610-615.
Externí odkaz:
https://www.jstor.org/stable/4523841
Publikováno v:
PALAIOS, 1997 Feb 01. 12(1), 71-83.
Externí odkaz:
https://www.jstor.org/stable/3515295
Autor:
Lucas G Dent, Samuel A Manning, Benjamin Kroeger, Audrey M Williams, Abdul Jabbar Saiful Hilmi, Luke Crea, Shu Kondo, Sally Horne-Badovinac, Kieran F Harvey
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008083 (2019)
How biochemical and mechanical information are integrated during tissue development is a central question in morphogenesis. In many biological systems, the PIX-GIT complex localises to focal adhesions and integrates both physical and chemical informa
Externí odkaz:
https://doaj.org/article/29a31f93b9954389abe3a2cab7cb394d
Autor:
C. Mallinckrodt, Y. Tian, P.S. Aisen, F. Barkhof, S. Cohen, G. Dent, O. Hansson, K. Harrison, T. Iwatsubo, C.J. Mummery, K.K. Muralidharan, I. Nestorov, L. Nisenbaum, R. Rajagovindan, C. von Hehn, C.H. van Dyck, B. Vellas, S. Wu, Y. Zhu, A. Sandrock, T. Chen, S. Budd Haeberlein
Publikováno v:
Mallinckrodt, C, Tian, Y, Aisen, P S, Barkhof, F, Cohen, S, Dent, G, Hansson, O, Harrison, K, Iwatsubo, T, Mummery, C J, Muralidharan, K K, Nestorov, I, Nisenbaum, L, Rajagovindan, R, von Hehn, C, van Dyck, C H, Vellas, B, Wu, S, Zhu, Y, Sandrock, A, Chen, T & Budd Haeberlein, S 2023, ' Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab ', Journal of Prevention of Alzheimer's Disease, vol. 10, no. 2, pp. 171-177 . https://doi.org/10.14283/jpad.2023.6
Journal of Prevention of Alzheimer's Disease, 10(2), 171-177. Springer International Publishing AG
Journal of Prevention of Alzheimer's Disease, 10(2), 171-177. Springer International Publishing AG
Objectives: Efficacy and safety results from the EMERGE (NCT02484547) and ENGAGE (NCT02477800) phase 3 studies of aducanumab in early Alzheimer’s disease (AD) have been published. In EMERGE, but not in ENGAGE, high-dose aducanumab demonstrated sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd07dbe73e27c792379e4f551475c168
https://research.vumc.nl/en/publications/18353bb7-a328-4866-843c-42c58403e679
https://research.vumc.nl/en/publications/18353bb7-a328-4866-843c-42c58403e679
Autor:
Schwimmer, David R., Williams, G. Dent
Publikováno v:
Journal of Vertebrate Paleontology, 1999 Sep . 19(3), 588-590.
Externí odkaz:
https://www.jstor.org/stable/4524018
Autor:
S. Budd Haeberlein, P.S. Aisen, F. Barkhof, S. Chalkias, T. Chen, S. Cohen, G. Dent, O. Hansson, K. Harrison, C. von Hehn, T. Iwatsubo, C. Mallinckrodt, C.J. Mummery, K.K. Muralidharan, I. Nestorov, L. Nisenbaum, R. Rajagovindan, L. Skordos, Y. Tian, C.H. van Dyck, B. Vellas, S. Wu, Y. Zhu, A. Sandrock
Publikováno v:
Journal of Prevention of Alzheimer's Disease, 9(2), 197-210. Springer International Publishing AG
Budd Haeberlein, S, Aisen, P S, Barkhof, F, Chalkias, S, Chen, T, Cohen, S, Dent, G, Hansson, O, Harrison, K, von Hehn, C, Iwatsubo, T, Mallinckrodt, C, Mummery, C J, Muralidharan, K K, Nestorov, I, Nisenbaum, L, Rajagovindan, R, Skordos, L, Tian, Y, van Dyck, C H, Vellas, B, Wu, S, Zhu, Y & Sandrock, A 2022, ' Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease ', Journal of Prevention of Alzheimer's Disease, vol. 9, no. 2, pp. 197-210 . https://doi.org/10.14283/jpad.2022.30
Budd Haeberlein, S, Aisen, P S, Barkhof, F, Chalkias, S, Chen, T, Cohen, S, Dent, G, Hansson, O, Harrison, K, von Hehn, C, Iwatsubo, T, Mallinckrodt, C, Mummery, C J, Muralidharan, K K, Nestorov, I, Nisenbaum, L, Rajagovindan, R, Skordos, L, Tian, Y, van Dyck, C H, Vellas, B, Wu, S, Zhu, Y & Sandrock, A 2022, ' Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease ', Journal of Prevention of Alzheimer's Disease, vol. 9, no. 2, pp. 197-210 . https://doi.org/10.14283/jpad.2022.30
Background: Alzheimer’s disease is a progressive, irreversible, and fatal disease for which accumulation of amyloid beta is thought to play a key role in pathogenesis. Aducanumab is a human monoclonal antibody directed against aggregated soluble an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25356f937683da76b27d9eec33c332a0
https://research.vumc.nl/en/publications/104cb695-ffcb-4502-aba8-9ab998dcbd40
https://research.vumc.nl/en/publications/104cb695-ffcb-4502-aba8-9ab998dcbd40
The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in PDAC tumours. Here, we characterised previously unknown endogenous RELA-GFP dynamics in PDAC cell lines by live single cell imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ea02b6878e6423ced5e817e2c20f5e
https://doi.org/10.1101/2022.01.19.476961
https://doi.org/10.1101/2022.01.19.476961
Autor:
Chris Bakal, Vincent Maioli, Nathan Curry, Hugh Sparks, Lucas G. Dent, Vicky Bousgouni, Christopher Dunsby, Ian Munro, Sunil Kumar
In order to invade 3D tissues, cancer cells dynamically change cell morphology in response to geometric and mechanical cues in the environment. But how cells determine their shape in 3D versus 2D environments is poorly understood. Studying 2D versus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4407ea2d84a258d9ba145292bda54f50
https://doi.org/10.1101/2021.10.11.463377
https://doi.org/10.1101/2021.10.11.463377
Publikováno v:
Journal of Paleontology, 1993 Mar 01. 67(2), 288-296.
Externí odkaz:
https://www.jstor.org/stable/1305997