Zobrazeno 1 - 10
of 24
pro vyhledávání: '"G. Danielli"'
Autor:
Sara G. Danielli, Yun Wei, Michael A. Dyer, Elizabeth Stewart, Heather Sheppard, Marco Wachtel, Beat W. Schäfer, Anand G. Patel, David M. Langenau
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Rhabdomyosarcoma (RMS) is a pediatric tumor that resembles undifferentiated muscle cells; yet the extent to which cell state heterogeneity is shared with human development has not been described. Using single-cell/nucleus RNA sequencing from
Externí odkaz:
https://doaj.org/article/e29faed2ad884c858ba654d0b6fb5c27
Autor:
Yaw Asante, Katharina Benischke, Issra Osman, Quy A. Ngo, Jakob Wurth, Dominik Laubscher, Hyunmin Kim, Bhavatharini Udhayakumar, Md Imdadul H. Khan, Diana H. Chin, Jadon Porch, Maharshi Chakraborty, Richard Sallari, Olivier Delattre, Sakina Zaidi, Sarah Morice, Didier Surdez, Sara G. Danielli, Beat W. Schäfer, Berkley E. Gryder, Marco Wachtel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Activation of oncogenic gene expression from long-range enhancers is initiated by the assembly of DNA-binding transcription factors (TF), leading to recruitment of co-activators such as CBP/p300 to modify the local genomic context and facili
Externí odkaz:
https://doaj.org/article/8b11c89f44b84a3f89f0cbe46cf89665
Autor:
Sara G. Danielli, Ermelinda Porpiglia, Andrea J. De Micheli, Natalia Navarro, Michael J. Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G. Marques, Stephanie Kasper, Peter K. Bode, Anton G. Henssen, Dennis Gürgen, Olivier Delattre, Didier Surdez, Josep Roma, Peter Bühlmann, Helen M. Blau, Marco Wachtel, Beat W. Schäfer
Publikováno v:
Science Advances, 9 (6)
Danielli, S G, Porpiglia, E, De Micheli, A J, Navarro, N, Zellinger, M J, Bechtold, I, Kisele, S, Volken, L, Marques, J G, Kasper, S, Bode, P K, Henssen, A G, Gürgen, D, Delattre, O, Surdez, D, Roma, J, Bühlmann, P, Blau, H M, Wachtel, M & Schäfer, B W 2023, ' Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance ', Science Advances, vol. 9, no. 6, eade9238 . https://doi.org/10.1126/sciadv.ade9238
Danielli, S G, Porpiglia, E, De Micheli, A J, Navarro, N, Zellinger, M J, Bechtold, I, Kisele, S, Volken, L, Marques, J G, Kasper, S, Bode, P K, Henssen, A G, Gürgen, D, Delattre, O, Surdez, D, Roma, J, Bühlmann, P, Blau, H M, Wachtel, M & Schäfer, B W 2023, ' Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance ', Science Advances, vol. 9, no. 6, eade9238 . https://doi.org/10.1126/sciadv.ade9238
Rhabdomyosarcoma (RMS) is a group of pediatric cancers with features of developing skeletal muscle. The cellular hierarchy and mechanisms leading to developmental arrest remain elusive. Here, we combined single-cell RNA sequencing, mass cytometry, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4a878ea2cde7eec5bf8ac9c8637212
https://hdl.handle.net/20.500.11850/598915
https://hdl.handle.net/20.500.11850/598915
Autor:
Olivia Ruhen, Nathalie S.M. Lak, Janine Stutterheim, Sara G. Danielli, Mathieu Chicard, Yasmine Iddir, Alexandra Saint-Charles, Virginia Di Paolo, Lucia Tombolan, Susanne A. Gatz, Ewa Aladowicz, Paula Proszek, Sabri Jamal, Reda Stankunaite, Deborah Hughes, Paul Carter, Elisa Izquierdo, Ajla Wasti, Julia C. Chisholm, Sally L. George, Erika Pace, Louis Chesler, Isabelle Aerts, Gaelle Pierron, Sakina Zaidi, Olivier Delattre, Didier Surdez, Anna Kelsey, Michael Hubank, Paolo Bonvini, Gianni Bisogno, Angela Di Giannatale, Gudrun Schleiermacher, Beat W. Schäfer, Godelieve A.M. Tytgat, Janet Shipley
Publikováno v:
JCO precision oncology. 6
PURPOSE Rhabdomyosarcomas (RMS) are rare neoplasms affecting children and young adults. Efforts to improve patient survival have been undermined by a lack of suitable disease markers. Plasma circulating tumor DNA (ctDNA) has shown promise as a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd26439d745faab9a7b2f16a3932ebe6
https://pubmed.ncbi.nlm.nih.gov/36265118
https://pubmed.ncbi.nlm.nih.gov/36265118
Autor:
Silvia Pomella, Sara G. Danielli, Rita Alaggio, Willemijn B. Breunis, Ebrahem Hamed, Joanna Selfe, Marco Wachtel, Zoe S. Walters, Beat W. Schäfer, Rossella Rota, Janet M. Shipley, Simone Hettmer
Publikováno v:
Cancers. 15:2823
Rhabdomyosarcoma (RMS), the most common soft-tissue sarcoma in children and adolescents, represents an aberrant form of skeletal muscle differentiation. Both skeletal muscle development, as well as regeneration of adult skeletal muscle are governed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1753d00911d8ddc89dd38ec357bb583
https://doi.org/10.3390/cancers15102823
https://doi.org/10.3390/cancers15102823
Autor:
Sara G Danielli, Ermelinda Porpiglia, Andrea J De Micheli, Natalia Navarro, Michael J Zellinger, Ingrid Bechtold, Samanta Kisele, Larissa Volken, Joana G Marques, Stephanie Kasper, Peter K Bode, Anton G Henssen, Dennis Gürgen, Josep Roma, Peter Bühlmann, Helen M Blau, Marco Wachtel, Beat W Schäfer
Rhabdomyosarcoma (RMS) is an aggressive human pediatric cancer. Despite robust expression of myogenic regulatory factors, RMS cells are blocked in a proliferative state and do not terminally differentiate. The extent to which the skeletal muscle line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::808d7d047fd026654a208f0ad8f2e083
https://doi.org/10.1101/2022.04.20.487706
https://doi.org/10.1101/2022.04.20.487706
Autor:
F. Lemanski, E. Tavares, G. Kohl Hammacher, J. V. Barcellos Zin, N. Mesquita Salvadori, A. Schuster Zagonel, G. Danielli, L. Crespi Corradi
Publikováno v:
69a Congresso Brasileiro 27° Congresso Latinoamericano de Coloproctologia 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a085adccb1b3fc94c2836ac8f38890
https://doi.org/10.1055/s-0041-1741674
https://doi.org/10.1055/s-0041-1741674
Autor:
F. Lemanski, L. Roberta Negrão, G. Kohl Hammacher, P. Bravo Araujo, C. A. Dos Santos Carneiro, N. Mesquita Salvadori, A. Schuster Zagonel, G. Danielli
Publikováno v:
69a Congresso Brasileiro 27° Congresso Latinoamericano de Coloproctologia 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0bc378d15870839308f6ae840379adb
https://doi.org/10.1055/s-0041-1741673
https://doi.org/10.1055/s-0041-1741673
Autor:
F. Lemanski, J. V. Barcellos Zin, G. Kohl Hammacher, P. Bravo Araujo, E. Tavares, L. Roberta Negrao, G. Danielli, A. Schuster Zagonel
Publikováno v:
69a Congresso Brasileiro 27° Congresso Latinoamericano de Coloproctologia 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6afbc73698374846f30533ac1a09c764
https://doi.org/10.1055/s-0041-1741985
https://doi.org/10.1055/s-0041-1741985
Autor:
F. Lemanski, M. D. Schmitz, J. F. Parizotto, C. A.D.S. Carneiro, G. Hammacher, G. Danielli, A. Schuster Zagonel, N. Mesquita Salvadori
Publikováno v:
69a Congresso Brasileiro 27° Congresso Latinoamericano de Coloproctologia 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c356050aaa85b38ae4c7181d1a965f39
https://doi.org/10.1055/s-0041-1741663
https://doi.org/10.1055/s-0041-1741663