Linkage stratification and mutation analysis at the Parkin locus identifies mutation positive Parkinson's disease families

Autor: William C. Nichols, J. Hubble, H. Fernandez, M. Aminoff, C. O'Brien, D. Truong, D. A. Grimes, A. Rudolph, F. Walker, L. Elmer, S. Factor, R. Kurlan, K. Blindauer, Paul J. Tuite, L. Seeberger, Richard B. Dewey, J. Rao, D. Jennings, P. M. Conneally, R. Pahwa, R. Hauser, W. Koller, T. Ajax, M. Fernandez, J. Sutton, B. Racette, R. Uitti, K. Sethi, A. Feigin, J. Jankovic, R. Pfeiffer, C. Serrano Ramos, M. Stacy, L. Shulman, M. F. Gordon, L. Sudarsky, K. Marek, J. Bertoni, V. Calabresse, M. Velickovic, R. Rodnitzyk, Juan Sanchez-Ramos, Sean K. Uniacke, P. Gordon, A. Dalvi, N. Hermanowicz, T. Zesiewicz, T. Simuni, U. Jung Kang, C. Shults, P. Lewitt, M. Leehey, Mayank Pathak, Tatiana Foroud, J. Carter, R. Saunders Pullman, B. Manyam, M. Panisset, Michael W. Pauciulo, G. D. Podakalny, T. Mendis, D. Simon, J. Friedman, W. Martin, Richard Camicioli, Joanne Wojcieszek, N. Pankratz, C. Halter, K. Marder, S. Reich, A. Nieves, A. Rajput, O. Suchowersky

Publikováno v: Journal of medical genetics. 39(7)

Parkinson's disease (PD) is one of the most common neurological disorders in humans with an overall prevalence of 1:1000 with the incidence increasing to as high as 3.4% among people aged 75 years.1,2 The clinical phenotype includes resting tremor, m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b725632ddb901f816fec5360003567d7
https://pubmed.ncbi.nlm.nih.gov/12114481