Zobrazeno 1 - 2
of 2
pro vyhledávání: '"G. D. Gungarova"'
Publikováno v:
Тонкие химические технологии, Vol 1, Iss 1, Pp 19-22 (2006)
Synthesis of purine 2'-deoxynucleoside analogues derivatives, named by using thioglycosides: 2',3'-dideoxyguanosine (3) and 2',3'-dideoxyguanosine (4) is described. This approach is based on condensation of S-glycoside (5) with silylated heterocyclic
Externí odkaz:
https://doaj.org/article/a9882f1c3a874faab559f8c425d64032
Autor:
V. I. Shvets, A. I. Davydova, A. M. Yurkevich, E. N. Savvateeva, Yu. G. Kirillova, G. D. Gungarova, A. S. Arkhipova, A. I. Lyutik
Publikováno v:
Pharmaceutical Chemistry Journal. 40:320-324
The synthesis of pharmacologically active 2′-deoxynucleoside analogs, namely 2′,3′-dideoxythymidine (I) and 2′,3′-dideoxy-3′-fluorothymidine (II), is described. The proposed approach consists in condensation of the corresponding thioglyco