Zobrazeno 1 - 10
of 43
pro vyhledávání: '"G. D. Bonnard"'
Autor:
B M Vose, G D Bonnard
Publikováno v:
The Journal of Immunology. 130:687-693
Human peripheral blood LGL that mediated NK and small T cells were isolated in high purity (98% by morphology) by density sedimentation on discontinuous Percoll gradients. The proliferative frequency of these subpopulations in the presence of lectin-
Publikováno v:
Scandinavian Journal of Immunology. 4:487-497
We have compared antibody-dependent cell-mediated cytotoxicity (ADCMC) of human peripheral blood leukocytes (PBL) in three model systems. target cells were 51Cr-labeled mouse mastocytoma cells, chicken erythrocytes (CRBC), and human erythrocytes (HRB
Publikováno v:
Blood. 48:809-816
The lack of a simple, rapid, and quantitative test of the functional activity of the monocyte has hampered studies of the contribution of this cell type to host defense and human disease. This report describes an assay of antibody-dependent cellular
Publikováno v:
The Journal of Immunology. 132:261-265
The regulation of the first cell cycle of human, activated (G1) PBL was analyzed by flow cytometry and [3H]thymidine incorporation. Endogenous IL 2 production was blocked in situ by pharmacologic concentration of DEX (100 to 1000 nM), resulting in an
Publikováno v:
Transplantation. 21:381-386
Mixed lymphocyte culture (MLC) responses of spleen cells from mice bearing tumors induced by murine sarcoma virus of the Moloney type (MSV) against allogeneic spleen cells were found to be markedly depressed, as estimated by three parameters: lymphob
Autor:
G. D. Bonnard, H R. MacDONALD
Publikováno v:
Scandinavian Journal of Immunology. 4:129-138
Some physical and mechanistic properties of cytotoxic lymphocytes and antibody-dependent killer cells were compared. Cytotoxic lymphocytes were measured by the cell-mediated lympholysis (CML) technique after sensitization of human peripheral blood le
Publikováno v:
The Journal of Immunology. 122:1489-1494
The specificity and the cells involved in natural cytotoxicity against tumor cells by fresh normal human peripheral blood mononuclear leukocytes have been extensively examined. Recently we have observed that removal of Fc receptor-positive cells from
Publikováno v:
Scandinavian Journal of Immunology. 3:97-106
The cytotoxicity of human peripheral blood lymphocytes (PBL), after a 6-day allogeneic stimulation in unidirectional mixed lymphocyte culture (UMLC). was studied. PBLs stimulated with phytohemagglutinin (PHA) and labeled with 51Cr were used .as targe
Publikováno v:
The Journal of Immunology. 123:2704-2708
The fate in culture of the T cell growth factor (TCGF), which is required for continued growth of human cultured T cells (CTC) in vitro, was studied. TCGF activity was stable for 7 days at 37°C. However, it was no longer detectable after incubation
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 116(2)
Cell-mediated cytotoxic responses against a syngeneic Gross virus-induced lymphoma, (C58NT)D, in W/Fu rats were generated in vitro by using mixed lymphocyte-tumor cell cultures. The source of responding cells was either spleens from normal rats or sp