Zobrazeno 1 - 10
of 232
pro vyhledávání: '"G. Cruzan"'
Publikováno v:
Regulatory Toxicology and Pharmacology. 66:24-29
Styrene (S) is lung tumorigenic in mice but not in rats. S and its alkene-oxidized metabolite styrene oxide (SO) were not lung toxic in CYP2F2(-/-) [knockout] mice, indicating S-induced mouse lung tumors are mediated through mouse-specific CYP2F2-gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8486b08a8456b08680161a63038b657c
https://doi.org/10.1016/j.yrtph.2013.02.008
https://doi.org/10.1016/j.yrtph.2013.02.008
Autor:
Gary W. Trimmer, F.T. Whitman, C.S. Nessel, Randi Hagemann, B.J. Simpson, Richard H. McKee, G. Cruzan, J.H. Urbanus, Robert A.J. Priston, C.R. Mackerer, A.J. Riley
Publikováno v:
Reproductive Toxicology. 14:337-353
Gasoline (CAS 86290-81-5) is one of the world's largest volume commercial products. Although numerous toxicology studies have been conducted, the potential for reproductive toxicity has not been directly assessed. Accordingly, a two-generation reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711b7d271d86c12cfe9181d0d9e30674
https://doi.org/10.1016/s0890-6238(00)00085-x
https://doi.org/10.1016/s0890-6238(00)00085-x
Autor:
J.V. Sousa, G. Cruzan, Arthur E. Putt, M.W. Machado, J.R. Hoberg, N.A. Garvey, J.R. Cushman, J.P. St. Laurent, E. Williams, M.C. Harrass, G.A. Rausina, J. Gilbert
Publikováno v:
Ecotoxicology and Environmental Safety. 37:173-180
The ecotoxicity of styrene was evaluated in acute toxicity studies of fathead minnows (Pimephales promelas), daphnids (Daphnia magna), amphipods (Hyalella azteca), and freshwater green algae (Selenastrum capricornutum), and a subacute toxicity study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d78239ac434dc9fd8e458e98eef8c3
https://doi.org/10.1006/eesa.1997.1540
https://doi.org/10.1006/eesa.1997.1540
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 62(1)
Styrene induces lung tumors in mice but not in rats. Although metabolism of styrene to 7,8-styrene oxide (SO) by CYP2E1 has been suggested as a mediator of styrene toxicity, lung toxicity is not attenuated in CYP2E1 knockout mice. However, styrene an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce6f0391d53edf1e8dd6d3f0bf6bfe1
https://pubmed.ncbi.nlm.nih.gov/22041433
https://pubmed.ncbi.nlm.nih.gov/22041433
Publikováno v:
Mutation research. 565(2)
Tertiary -Butyl alcohol (TBA), tertiary -butyl acetate™ (TBAc™) and methyl tertiary -butyl ether (MTBE) are chemicals to which the general public may be exposed either directly or as a result of their metabolism. There is little evidence that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a982fc6f80d938f2af789e5a3b787f
https://pubmed.ncbi.nlm.nih.gov/15661616
https://pubmed.ncbi.nlm.nih.gov/15661616
Autor:
G, Cruzan, J R, Cushman, L S, Andrews, G C, Granville, K A, Johnson, C J, Hardy, D W, Coombs, P A, Mullins, W R, Brown
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 46(2)
Groups of 70 male and 70 female Charles River CD (Sprague-Dawley-derived) rats were exposed whole body to styrene vapor at 0, 50, 200, 500, or 1000 ppm 6 h/day 5 days/week for 104 weeks. The rats were observed daily, body weights and food and water c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8639f547a3b9be3dbf75a8d7ebe4169
https://pubmed.ncbi.nlm.nih.gov/10048130
https://pubmed.ncbi.nlm.nih.gov/10048130
Autor:
C S, Nessel, R A, Priston, R H, McKee, G, Cruzan, A J, Riley, R, Hagemann, R T, Plutnick, B J, Simpson
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 44(1)
The role of skin irritation and other factors on the tumorigenic activity of petroleum middle distillates (PMDs) in mice was examined in a comprehensive research program. The program culminated in a 2-year dermal carcinogenicity study which compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::742dabe65988adbf14cbeb9fab5d017b
https://pubmed.ncbi.nlm.nih.gov/9720137
https://pubmed.ncbi.nlm.nih.gov/9720137
Autor:
SHEPHERD, LOIS1, CHEN, DONNA1
Publikováno v:
Indiana Law Journal. 2024, Vol. 99 Issue 3, p933-1014. 82p.
Autor:
Lee, Kristina1
Publikováno v:
University of the Pacific Law Review. May2024, Vol. 55 Issue 3, p533-564. 32p.