Zobrazeno 1 - 10
of 84
pro vyhledávání: '"G. Cristina Brailoiu"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5160 (2021)
Orexin A, an endogenous peptide involved in several functions including reward, acts via activation of orexin receptors OX1 and OX2, Gq-coupled GPCRs. We examined the effect of a selective OX1 agonist, OXA (17-33) on cytosolic calcium concentration,
Externí odkaz:
https://doaj.org/article/25e34eda250646b18f9dec117b4f75c0
Autor:
Eugen Brailoiu, Sumita Chakraborty, G. Cristina Brailoiu, Pingwei Zhao, Jeffrey L. Barr, Marc A. Ilies, Ellen M. Unterwald, Mary E. Abood, Colin W. Taylor
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 330-337.e4 (2019)
Summary: Sigma-1 receptors (Sig-1Rs) are integral ER membrane proteins. They bind diverse ligands, including psychoactive drugs, and regulate many signaling proteins, including the inositol 1,4,5-trisphosphate receptors (IP3Rs) that release Ca2+ from
Externí odkaz:
https://doaj.org/article/bba4f71ea52a4806843616fb0bce4be7
Autor:
Karan Modi, Scott Lawson, Guanglin Chen, Deepthi Tumuluri, Inga Rekhtman, Michael Kurtz, G. Cristina Brailoiu, Qiao-Hong Chen, Ashakumary Lakshmikuttyamma
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5777 (2020)
Curcumin has been well studied for its anti-oxidant, anti-inflammatory, and anti-cancer action. Its potential as a therapy is limited due to its low bioavailability and rapid metabolism. To overcome these challenges, investigators are developing curc
Externí odkaz:
https://doaj.org/article/dba4ff9c92224066afe6ab1528b4bb80
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5160, p 5160 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5160, p 5160 (2021)
Orexin A, an endogenous peptide involved in several functions including reward, acts via activation of orexin receptors OX1 and OX2, Gq-coupled GPCRs. We examined the effect of a selective OX1 agonist, OXA (17-33) on cytosolic calcium concentration,
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2367
We report here the method of visualization of brain microcirculation and assessment of blood-brain barrier (BBB) permeability changes using the miniature integrated fluorescence microscope (i.e., miniscope) technology in awake, freely moving rats. Th
Publikováno v:
Methods in Molecular Biology ISBN: 9781071616727
We report here the method of visualization of brain microcirculation and assessment of blood-brain barrier (BBB) permeability changes using the miniature integrated fluorescence microscope (i.e., miniscope) technology in awake, freely moving rats. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec1d78fae37422d3cb9c503a38616a61
https://doi.org/10.1007/7651_2020_315
https://doi.org/10.1007/7651_2020_315
Publikováno v:
Neurosci Lett
Docosahexaenoic acid (DHA) an omega-3 polyunsaturated fatty acid, is an agonist of FFA1 receptor. DHA administration reduces the heart rate via unclear mechanisms. We examined the effect of DHA on neurons of nucleus ambiguus that provide the parasymp
Publikováno v:
Neuroscience. 377:105-113
Platelet-activating factor (PAF) is a potent phospholipid mediator that exerts various pathophysiological effects by interacting with a G protein-coupled receptor. PAF has been reported to increase the permeability of the blood-brain barrier (BBB) vi
Autor:
Matthew McGuire, Elena Deliu, G. Cristina Brailoiu, Shadaria A. Shuler, Mary E. Abood, Eugen Brailoiu, Jeffrey L. Barr
Publikováno v:
Neuroscience. 365:23-32
Bradykinin (BK), a component of the kallikrein-kininogen-kinin system exerts multiple effects via B1 and B2 receptor activation. In the cardiovascular system, bradykinin has cardioprotective and vasodilator properties. We investigated the effect of B
Autor:
Ellen M. Unterwald, Eugen Brailoiu, Mary E. Abood, Scott M. Rawls, Jeffrey L. Barr, G. Cristina Brailoiu
Publikováno v:
Drug Alcohol Depend
Background Cocaine has a variety of negative effects on the central nervous system, including reports of decreased barrier function of brain microvascular endothelial cells. However, few studies have directly shown the effects of cocaine on blood-bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0b399e9e506201f8fe7244b8a3ab92
https://europepmc.org/articles/PMC6980767/
https://europepmc.org/articles/PMC6980767/