Zobrazeno 1 - 10
of 39
pro vyhledávání: '"G. Chimote"'
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 370:6-14
The pathophysiology of meconium aspiration syndrome (MAS) is attributed in part to the development of lung surfactant dysfunction in vivo. Meconium (the first excrement of the newborn) and its components are responsible for development of lung surfac
Autor:
Rangan Banerjee, G. Chimote
Publikováno v:
Journal of Biomedical Materials Research Part A. :281-292
Pulmonary tuberculosis is associated with a year-long chemotherapy, poor alveolar drug levels, drug-related systemic toxicity, and patient noncompliance. In this study, exogenous pulmonary surfactant is proposed as a drug carrier for antitubercular d
Autor:
Rangan Banerjee, G. Chimote
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 338:7-14
Lung surfactant is a lipoprotein Mixture synthesized by the type [I alveolar cells in the lungs and lines the air-aqueous interface. It is essential for stabilizing the pulmonary alveoli. Deficiency or dysfunction of the surfactant due to chemicals o
Autor:
G. Chimote, Rangan Banerjee
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 65:120-125
Molecular interactions between mycobacterial cell wall lipid, cord factor (CF) and the abundant surfactant lipid, dipalmitoylphosphatidylcholine (DPPC) were investigated using Langmuir monolayers at physiological temperatures (37 °C). Surface topogr
Autor:
Rangan Banerjee, G. Chimote
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 94(1)
In this study, exogenous pulmonary surfactant was evaluated as an inhalable drug carrier for antitubercular drug isoniazid (INH). Isoniazid-entrapped liposomes of dipalmitoyl-phosphatidylcholine (DPPC) (the most abundant lipid of lung surfactant and
Autor:
G. Chimote, Rangan Banerjee
Publikováno v:
Respiratory physiologyneurobiology. 162(1)
In this study, the effect of mycobacterial lipids on the surface activity of lung surfactant was evaluated. Mycolic acid and cord factor, the most abundant surface active lipids of the mycobacterial cell wall when combined with Curosurf (TM) led to a
Autor:
G. Chimote, Rangan Banerjee
Publikováno v:
Journal of colloid and interface science. 328(2)
In pulmonary tuberculosis, Mycobacterium tuberculosis lies in close physical proximity to alveolar surfactant. Cell walls of the mycobacteria contain loosely bound, detachable surface-active lipids. In this study, the effect of mycolic acid (MA), the
Evaluation of antitubercular drug insertion into preformed dipalmitoylphosphatidylcholine monolayers
Autor:
G. Chimote, Rangan Banerjee
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 62(2)
Insertion profiles of antitubercular drugs isoniazid (INH), rifampicin (RFM) and ethambutol (ETH) into dipalmitoylphosphatidylcholine (DPPC) membrane models were evaluated by Langmuir monolayer technique. Maximum drug insertion into DPPC monolayer wa
Autor:
Rangan Banerjee, G. Chimote
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 45(3-4)
In pulmonary tuberculosis, Mycobacterium tuberculosis bacteria reside in the alveoli and are in close proximity with the alveolar surfactant. Mycolic acid in its free form and as cord factor, constitute the major lipids of the mycobacterial cell wall
Autor:
G. Chimote, Rangan Banerjee
Publikováno v:
Respiratory physiologyneurobiology. 145(1)
The year long chemotherapy in pulmonary tuberculosis results in dose related side effects and may not reach atelectatic areas. On account of its spreading properties and the ability to re-expand atelectatic areas, exogenous surfactant may act as a pu