Zobrazeno 1 - 10
of 22
pro vyhledávání: '"G. Celine Han"'
Autor:
Ryan B. Corcoran, Eliezer M. Van Allen, A. John Iafrate, Dora Dias-Santagata, Nicholas A. Jessop, Joseph M. Gurski, Catriona B. Hong, Brandon Nadres, Emily E. Van Seventer, Theodore S. Hong, Janet E. Murphy, Jason E. Faris, Eunice L. Kwak, Jeffrey W. Clark, Jill N. Allen, Aparna R. Parikh, Lifeng Chen, Heather A. Shahzade, Leanne G. Ahronian, David Liu, G. Celine Han, Marianna Kleyman, Mehlika Hazar-Rethinam
Supplementary Figures, Tables, Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ce7541270ee6481b31d9cc32b0e30e
https://doi.org/10.1158/2159-8290.22532971
https://doi.org/10.1158/2159-8290.22532971
Autor:
Padmanee Sharma, Andrea Necchi, Arlene Siefker-Radtke, Sandra Collette, Gary Grossfeld, G. Celine Han, Peter M. Szabo, Abdel Saci, Matthew D. Galsky
This appendix includes all supplemental tables and figures referenced in the article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54365bbaa6e8ee8af854bcfc9a0700b5
https://doi.org/10.1158/1078-0432.22476537
https://doi.org/10.1158/1078-0432.22476537
Autor:
Hakim Mahammedi, Matthew D. Galsky, Marika Ciprotti, Gwenaelle Gravis, Abdel Saci, Aude Flechon, Russell K. Pachynski, Yanhua Hu, Sumit K. Subudhi, Karim Fizazi, Akash Patnaik, Vivek Narayan, Padmanee Sharma, G. Celine Han, Burcin Simsek
Publikováno v:
Cancer cell. 38(4)
Summary Metastatic castration-resistant prostate cancer (mCRPC) is immunologically "cold" and predominantly resistant to immune checkpoint therapy due to few tumor-infiltrating T cells. Ipilimumab (anti-CTLA-4) or anti-PD-1/PD-L1 monotherapy failed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31a723e080c6074cdfcc96102df0c3d
https://pubmed.ncbi.nlm.nih.gov/33049204
https://pubmed.ncbi.nlm.nih.gov/33049204
Autor:
Abdel Saci, Padmanee Sharma, Arlene O. Siefker-Radtke, Matthew D. Galsky, Péter Szabó, G. Celine Han, Sandra Collette, Andrea Necchi, Gary D. Grossfeld
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(19)
Purpose:We report efficacy and safety with extended follow-up, and exploratory biomarker analyses from the phase II CheckMate 275 trial to identify biomarkers of response to nivolumab in platinum-resistant metastatic or unresectable urothelial carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597e32e1d86fc4c58b7c5fffb7d2ca56
https://pubmed.ncbi.nlm.nih.gov/32759359
https://pubmed.ncbi.nlm.nih.gov/32759359
Autor:
G. Celine Han, Heather A. Shahzade, Mehlika Hazar-Rethinam, Eunice L. Kwak, Leanne G. Ahronian, David Liu, Jeffrey W. Clark, Aparna Raj Parikh, Theodore S. Hong, Ryan B. Corcoran, Eliezer M. Van Allen, Jason E. Faris, Emily E. Van Seventer, Jill N. Allen, Catriona B. Hong, Nicholas A. Jessop, Joseph M. Gurski, Marianna Kleyman, Janet E. Murphy, Lifeng Chen, A. John Iafrate, Brandon Nadres, Dora Dias-Santagata
Publikováno v:
Cancer Discovery. 8:417-427
Clonal heterogeneity associated with acquired resistance presents a critical therapeutic challenge. Whole-exome sequencing of paired tumor biopsies and targeted sequencing of cell-free DNA (cfDNA) from patients with BRAFV600E colorectal cancer receiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b93334d267a1925221e3cd24a72212
https://doi.org/10.1158/2159-8290.cd-17-1227
https://doi.org/10.1158/2159-8290.cd-17-1227
Autor:
Zhenwei Zhang, Scott L. Carter, William C. Hahn, Rana R. McKay, Steven P. Balk, Carrie Cibulskis, Glenn J. Bubley, Justin H. Hwang, G. Celine Han, Mary-Ellen Taplin, Stephanie A. Wankowicz, Varand Ghazikhanian, Eliezer M. Van Allen, Glenn C. Gaviola, David Liu
Publikováno v:
JCO Precision Oncology
Purpose Patients with castration-resistant prostate cancer (CRPC) receive second-generation androgen-deprivation therapy, but frequently experience relapse or do not respond. Understanding the genetic mechanisms of resistance will help to identify st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9c07daa004e5531159dfdb30f59056
https://doi.org/10.1200/po.17.00140
https://doi.org/10.1200/po.17.00140
Autor:
Scott L. Carter, G. Celine Han, Clare Turnbull, Jennifer L. Guerriero, Christopher Sweeney, Gad Getz, Rameen Beroukhim, Steven E. Schumacher, Brandon Bernard, Eliezer M. Van Allen, Amaro Taylor-Weiner, Travis I. Zack, Kevin Litchfield, Anita Reddy, Stacey Gabriel, Elizabeth O'Donnell, Ali Amin-Mansour, Saud H. AlDubayan, Anthony Letai, Michelle S. Hirsch
Publikováno v:
Nature. 540:114-118
Germ-cell tumours (GCTs) are derived from germ cells and occur most frequently in the testes. GCTs are histologically heterogeneous and distinctly curable with chemotherapy. Gains of chromosome arm 12p and aneuploidy are nearly universal in GCTs, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91e5005fe6126c2905b0c6041e517ed
https://doi.org/10.1038/nature20596
https://doi.org/10.1038/nature20596
Autor:
Maria Long, Vinesh Vinayachandran, Shaun Mahony, Ka Yim Chan-Salis, Alain R. Bataille, G. Celine Han, Bongsoo Park, B. Franklin Pugh, Cheryl A. Keller, Ross C. Hardison
Publikováno v:
Molecular and Cellular Biology
Erythroid development and differentiation from multiprogenitor cells into red blood cells requires precise transcriptional regulation. Key erythroid transcription factors, GATA1 and TAL1, cooperate, along with other proteins, to regulate many aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a5b96733fd0693297c39540ecb0d51
http://europepmc.org/articles/PMC4702602
http://europepmc.org/articles/PMC4702602
Publikováno v:
Cancer Research. 80:2008-2008
Background: Tumor mutational burden (TMB) has been associated with efficacy of immune checkpoint therapy and is being investigated as a potential biomarker in several tumor types. The foundational studies evaluating TMB in clinical trials have not ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de658f19e690a83b8698433a96712c5
https://doi.org/10.1158/1538-7445.am2020-2008
https://doi.org/10.1158/1538-7445.am2020-2008
Autor:
Saud H. AlDubayan, Marios Giannakis, Nathanael D. Moore, G. Celine Han, Brendan Reardon, Tsuyoshi Hamada, Xinmeng Jasmine Mu, Reiko Nishihara, Zhirong Qian, Li Liu, Matthew B. Yurgelun, Sapna Syngal, Levi A. Garraway, Shuji Ogino, Charles S. Fuchs, Eliezer M. Van Allen
Colorectal cancer (CRC) heritability has been estimated to be around 30%. However, mutations in the known CRC susceptibility genes explain CRC risk in under 10% of the cases. Germline mutations in DNA-repair genes (DRGs) have recently been reported i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d098efb0a394bfee603306b835c333b1
https://doi.org/10.1101/256917
https://doi.org/10.1101/256917