Výsledky vyhledávání - "G. C. Saueracker"

CHARACTERIZATION OF MHC ANCESTRAL HAPLOTYPES ASSOCIATED WITH INSULIN-DEPENDENT DIABETES MELLITUS: EVIDENCE FOR INVOLVEMENT OF NON-HLA GENES

Autor: G. C. Saueracker, A. L. Leaver, Frank T. Christiansen, R. L. Dawkins, K. Tokunaga, Paul U. Cameron

Publikováno v: European Journal of Immunogenetics. 17:379-386

SUMMARY Insulin-dependent diabetes mellitus (IDDM) is associated with several DR3- or DR4-containing ancestral haplotypes (AHs). Using pulsed field gel electrophoresis (PFGE), long range maps of 35 haplotypes have been derived and classified. Two dia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7948461f5286596ef3451002acb31200
https://doi.org/10.1111/j.1744-313x.1990.tb00889.x

Zobrazit plný text záznamu

Supratypes and ancestral haplotypes in IDDM: Potential importance of central non-HLA MHC genes

Autor: Emma Martin, Peter H. Kay, Roger L. Dawkins, G. C. Saueracker, Anne Leaver, Frank T. Christiansen

Publikováno v: Journal of Autoimmunity. 3:63-68

Juvenile insulin-dependent diabetes mellitus develops in susceptible children exposed to unknown environmental factors. If the genes responsible for susceptibility could be identified, it should be possible to understand the method of injury to beta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b203ebb0580b4424b89832ffdfbb7a
https://doi.org/10.1016/s0896-8411(09)90011-7

Zobrazit plný text záznamu

Pulsed field electrophoresis identifies the possible locations of diabetogenic genes contained within MHC ancestral haplotypes

Autor: Frank T. Christiansen, Roger L. Dawkins, G. C. Saueracker

Publikováno v: Journal of Autoimmunity. 3:57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22ec489cd05bd577d26fcd7b74588126
https://doi.org/10.1016/0896-8411(90)90034-p

Zobrazit plný text záznamu

Some Supratypes Extend to DQ

Autor: Roger L. Dawkins, G. C. Saueracker, E. Martin

Publikováno v: Immunobiology of HLA ISBN: 9783662389805

Supratypes are particular combinations of alleles at multiple MHC loci which occur in a population. For many diseases, supratypes provide the best marker for the disease gene within the MHC (1). Supratypes are predictable, they identify alleles at in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09da9a0c789620f719066d54bf041a5b
https://doi.org/10.1007/978-3-662-39946-0_112

Zobrazit plný text záznamu

Extensive deletions and insertions in different MHC supratypes detected by pusled field gel electrophoresis

Autor: K. Tokunaga, G. C. Saueracker, F.T. Christiansen, P. H. Kay, R. L. Dawkins, R Anand

Publikováno v: The Journal of Experimental Medicine

The genomic organization of the human MHC was examined in multiple examples of six different supratypes using pulsed field electrophoresis (PFGE) after digestion of genomic DNA with infrequency cutting restriction endonucleases. Differences in restri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3462e4b0b1646626dcc08e9442518d32
https://pubmed.ncbi.nlm.nih.gov/3171479

Zobrazit plný text záznamu